Hongbin Wang Ph.D.
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Protein kinase C and cancer: what we know and what we do not
R Garg, LG Benedetti, MB Abera, H Wang, M Abba, MG Kazanietz
Oncogene 33 (45), 5225-5237, 2014
Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer
MS Sosa, C Lopez-Haber, C Yang, HB Wang, MA Lemmon, JM Busillo, ...
Molecular cell 40 (6), 877-892, 2010
Characterization of the Rac-GAP (Rac-GTPase-activating protein) activity of β2-chimaerin, a ‘non-protein kinase C’phorbol ester receptor
MJ Caloca, HB Wang, MG Kazanietz
Biochemical Journal 375 (2), 313-321, 2003
Phorbol esters and related analogs regulate the subcellular localization of β2-chimaerin, a non-protein kinase C phorbol ester receptor
MJ Caloca, HB Wang, A Delemos, S Wang, MG Kazanietz
Journal of Biological Chemistry 276 (21), 18303-18312, 2001
Pharmacology of the receptors for the phorbol ester tumor promoters: multiple receptors with different biochemical properties
MG Kazanietz, MJ Caloca, P Eroles, T Fujii, ML Garcıa-Bermejo, M Reilly, ...
Biochemical pharmacology 60 (10), 1417-1424, 2000
Chimaerins, novel non-protein kinase C phorbol ester receptors, associate with Tmp21-I (p23): evidence for a novel anchoring mechanism involving the chimaerin C1 domain
HB Wang, MG Kazanietz
Journal of Biological Chemistry 277 (6), 4541-4550, 2002
Haploinsufficiency for the murine orthologue of Chlamydomonas PF20 disrupts spermatogenesis
Z Zhang, I Kostetskii, SB Moss, BH Jones, C Ho, H Wang, T Kishida, ...
Proceedings of the National Academy of Sciences 101 (35), 12946-12951, 2004
Activation of nuclear factor κB (NF-κB) in prostate cancer is mediated by protein kinase C ϵ (PKCϵ)
R Garg, J Blando, CJ Perez, HB Wang, FJ Benavides, MG Kazanietz
Journal of Biological Chemistry 287 (44), 37570-37582, 2012
Phospholipase Cγ/diacylglycerol‐dependent activation of β2‐chimaerin restricts EGF‐induced Rac signaling
HB Wang, C Yang, FC Leskow, J Sun, B Canagarajah, JH Hurley, ...
The EMBO journal 25 (10), 2062-2074, 2006
The RacGAP β2-Chimaerin selectively mediates axonal pruning in the hippocampus
MM Riccomagno, A Hurtado, HB Wang, JGJ Macopson, EM Griner, A Betz, ...
Cell 149 (7), 1594-1606, 2012
Downregulation of Rap1GAP contributes to Ras transformation
OM Tsygankova, GV Prendergast, K Puttaswamy, Y Wang, MD Feldman, ...
Molecular and cellular biology 27 (19), 6647-6658, 2007
Complement-activation fragment C4a mediates effector functions by binding as untethered agonist to protease-activated receptors 1 and 4.
HB Wang, D Ricklin, J Lambris
Proc Natl Acad Sci U S A. 114 (41), 10948-10953, 2017
The zebrafish homologue of mammalian chimerin Rac-GAPs is implicated in epiboly progression during development
FC Leskow, BA Holloway, HB Wang, MC Mullins, MG Kazanietz
Proceedings of the National Academy of Sciences 103 (14), 5373-5378, 2006
Esculentoside A inhibits tumor necrosis factor, interleukin-1, and interleukin-6 production induced by lipopolysaccharide in mice
DW Ju, QY Zheng, X Cao, J Fang, HB Wang
Pharmacology 56 (4), 187-195, 1998
p23/Tmp21 associates with protein kinase Cδ (PKCδ) and modulates its apoptotic function
HB Wang, L Xiao, MG Kazanietz
Journal of Biological Chemistry 286 (18), 15821-15831, 2011
Effects of esculentoside A on production of interleukin-1, 2, and prostaglandin E~ 2
ZY Xiao, QY Zheng, YY Jiang, B Zhou, M Yin, HB Wang, JP Zhang
Acta pharmacologica Sinica 25 (6), 817-821, 2004
Tumor cell migration and invasion are enhanced by depletion of Rap1 GTPase-activating protein (Rap1GAP)
OM Tsygankova, H Wang, JL Meinkoth
Journal of Biological Chemistry 288 (34), 24636-24646, 2013
p23/Tmp21 differentially targets the Rac-GAP β2-chimaerin and protein kinase C via their C1 domains
HB Wang, MG Kazanietz
Molecular biology of the cell 21 (8), 1398-1408, 2010
Transcriptional regulation of oncogenic protein kinase Cϵ (PKCϵ) by STAT1 and Sp1 proteins
HB Wang, A Gutierrez-Uzquiza, R Garg, L Barrio-Real, MB Abera, ...
Journal of Biological Chemistry 289 (28), 19823-19838, 2014
Surfactant protein D‐coated Klebsiella pneumoniae stimulates cytokine production in mononuclear phagocytes
Y Keisari, H Wang, A Mesika, R Matatov, L Nissimov, E Crouch, I Ofek
Journal of leukocyte biology 70 (1), 135-141, 2001
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