Srinivasa Murty Srinivasula
Srinivasa Murty Srinivasula
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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
P Li, D Nijhawan, I Budihardjo, SM Srinivasula, M Ahmad, ES Alnemri, ...
Cell 91 (4), 479-489, 1997
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
autophagy 12 (1), 1-222, 2016
IAPs block apoptotic events induced by caspase‐8 and cytochrome c by direct inhibition of distinct caspases
QL Deveraux, N Roy, HR Stennicke, T Van Arsdale, Q Zhou, ...
The EMBO journal 17 (8), 2215-2223, 1998
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
SM Srinivasula, M Ahmad, T Fernandes-Alnemri, ES Alnemri
Molecular cell 1 (7), 949-957, 1998
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
JL Wang, D Liu, ZJ Zhang, S Shan, X Han, SM Srinivasula, CM Croce, ...
Proceedings of the National Academy of Sciences 97 (13), 7124-7129, 2000
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
SM Srinivasula, R Hegde, A Saleh, P Datta, E Shiozaki, J Chai, RA Lee, ...
Nature 410 (6824), 112-116, 2001
Negative regulation of the Apaf-1 apoptosome by Hsp70
A Saleh, SM Srinivasula, L Balkir, PD Robbins, ES Alnemri
Nature cell biology 2 (8), 476-483, 2000
In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains
T Fernandes-Alnemri, RC Armstrong, J Krebs, SM Srinivasula, L Wang, ...
Proceedings of the National Academy of Sciences 93 (15), 7464-7469, 1996
Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction
R Hegde, SM Srinivasula, ZJ Zhang, R Wassell, R Mukattash, L Cilenti, ...
Journal of Biological Chemistry 277 (1), 432-438, 2002
Mechanism of XIAP-mediated inhibition of caspase-9
EN Shiozaki, J Chai, DJ Rigotti, SJ Riedl, P Li, SM Srinivasula, ...
Molecular cell 11 (2), 519-527, 2003
Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL
M MacFarlane, M Ahmad, SM Srinivasula, T Fernandes-Alnemri, ...
Journal of Biological Chemistry 272 (41), 25417-25420, 1997
Structural basis of caspase-7 inhibition by XIAP
J Chai, E Shiozaki, SM Srinivasula, Q Wu, P Dataa, ES Alnemri, Y Shi
Cell 104 (5), 769-780, 2001
Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases
SM Srinivasula, M Ahmad, T Fernandes-Alnemri, G Litwack, ES Alnemri
Proceedings of the National Academy of Sciences 93 (25), 14486-14491, 1996
Negative regulation of cytochrome c‐mediated oligomerization of Apaf‐1 and activation of procaspase‐9 by heat shock protein 90
P Pandey, A Saleh, A Nakazawa, S Kumar, SM Srinivasula, V Kumar, ...
The EMBO journal 19 (16), 4310-4322, 2000
Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
A Saleh, SM Srinivasula, S Acharya, R Fishel, ES Alnemri
Journal of Biological Chemistry 274 (25), 17941-17945, 1999
Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria
Y Guo, SM Srinivasula, A Druilhe, T Fernandes-Alnemri, ES Alnemri
Journal of Biological Chemistry 277 (16), 13430-13437, 2002
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-κB activation
CJ Wu, DB Conze, T Li, SM Srinivasula, JD Ashwell
Nature cell biology 8 (4), 398-406, 2006
IAPs: what's in a name?
SM Srinivasula, JD Ashwell
Molecular cell 30 (2), 123-135, 2008
The PYRIN-CARD protein ASC is an activating adaptor for caspase-1
SM Srinivasula, JL Poyet, M Razmara, P Datta, ZJ Zhang, ES Alnemri
Journal of Biological Chemistry 277 (24), 21119-21122, 2002
Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms
M Saleh, JP Vaillancourt, RK Graham, M Huyck, SM Srinivasula, ...
Nature 429 (6987), 75-79, 2004
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