Garnett Kelsoe
Garnett Kelsoe
James B. Duke Professor of Immunology, Duke University
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Intraclonal generation of antibody mutants in germinal centres
J Jacob, G Kelsoe, K Rajewsky, U Weiss
Nature 354 (6352), 389-392, 1991
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
HX Liao, R Lynch, T Zhou, F Gao, SM Alam, SD Boyd, AZ Fire, KM Roskin, ...
Nature 496 (7446), 469-476, 2013
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. I. The architecture and dynamics of responding cell populations.
J Jacob, R Kassir, G Kelsoe
The Journal of experimental medicine 173 (5), 1165-1175, 1991
Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers.
S Han, K Hathcock, B Zheng, TB Kepler, R Hodes, G Kelsoe
Journal of immunology (Baltimore, Md.: 1950) 155 (2), 556-567, 1995
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal …
J Jacob, G Kelsoe
The Journal of experimental medicine 176 (3), 679-687, 1992
B-cell–lineage immunogen design in vaccine development with HIV-1 as a case study
BF Haynes, G Kelsoe, SC Harrison, TB Kepler
Nature biotechnology 30 (5), 423-433, 2012
Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors
M Bonsignori, KK Hwang, X Chen, CY Tsao, L Morris, E Gray, DJ Marshall, ...
Journal of virology 85 (19), 9998-10009, 2011
Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells
A Caro-Maldonado, R Wang, AG Nichols, M Kuraoka, S Milasta, LD Sun, ...
The Journal of Immunology 192 (8), 3626-3636, 2014
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. III. The kinetics of V region mutation and selection in germinal center B cells.
J Jacob, J Przylepa, C Miller, G Kelsoe
The Journal of experimental medicine 178 (4), 1293-1307, 1993
Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice
DJ DiLillo, Y Hamaguchi, Y Ueda, K Yang, J Uchida, KM Haas, G Kelsoe, ...
The Journal of Immunology 180 (1), 361-371, 2008
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. V. Affinity maturation develops in two stages of clonal selection
Y Takahashi, PR Dutta, DM Cerasoli, G Kelsoe
The Journal of experimental medicine 187 (6), 885-895, 1998
Regulation of the B cell response to T-dependent antigens by classical pathway complement.
MB Fischer, M Ma, S Goerg, X Zhou, J Xia, O Finco, S Han, G Kelsoe, ...
Journal of immunology (Baltimore, Md.: 1950) 157 (2), 549-556, 1996
Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow
Y Ueda, M Kondo, G Kelsoe
The Journal of experimental medicine 201 (11), 1771-1780, 2005
Life and death in germinal centers (redux)
G Kelsoe
Immunity 4 (2), 107-111, 1996
Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells
S Han, B Zheng, DG Schatz, E Spanopoulou, G Kelsoe
Science 274 (5295), 2094-2097, 1996
V (D) J recombinase activity in a subset of germinal center B lymphocytes
S Han, SR Dillon, B Zheng, M Shimoda, MS Schlissel, G Kelsoe
Science 278 (5336), 301-305, 1997
Identification of a CD4-binding-site antibody to HIV that evolved near-pan neutralization breadth
J Huang, BH Kang, E Ishida, T Zhou, T Griesman, Z Sheng, F Wu, ...
Immunity 45 (5), 1108-1121, 2016
Dependence of germinal center B cells on expression of CD21/CD35 for survival
MB Fischer, S Goerg, LM Shen, AP Prodeus, CC Goodnow, G Kelsoe, ...
Science 280 (5363), 582-585, 1998
The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 …
SM Alam, M McAdams, D Boren, M Rak, RM Scearce, F Gao, ...
The Journal of Immunology 178 (7), 4424-4435, 2007
Maturation pathway from germline to broad HIV-1 neutralizer of a CD4-mimic antibody
M Bonsignori, T Zhou, Z Sheng, L Chen, F Gao, MG Joyce, G Ozorowski, ...
Cell 165 (2), 449-463, 2016
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