Evolution of genes and genomes on the Drosophila phylogeny AG Clark, MB Eisen, DR Smith, CM Bergman, B Oliver, TA Markow, ... Nature 450 (7167), 203-18, 2007 | 2248 | 2007 |
KRAS and YAP1 converge to regulate EMT and tumor survival DD Shao, W Xue, EB Krall, A Bhutkar, F Piccioni, X Wang, AC Schinzel, ... Cell 158 (1), 171-184, 2014 | 736 | 2014 |
Commensal microbiota promote lung cancer development via γδ T cells C Jin, GK Lagoudas, C Zhao, S Bullman, A Bhutkar, B Hu, S Ameh, ... Cell 176 (5), 998-1013. e16, 2019 | 709 | 2019 |
Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis R Romero, VI Sayin, SM Davidson, MR Bauer, SX Singh, SE LeBoeuf, ... Nature medicine 23 (11), 1362-1368, 2017 | 534 | 2017 |
Poly (ADP-ribose) regulates stress responses and microRNA activity in the cytoplasm AKL Leung, S Vyas, JE Rood, A Bhutkar, PA Sharp, P Chang Molecular cell 42 (4), 489-499, 2011 | 475 | 2011 |
Circadian rhythm disruption promotes lung tumorigenesis T Papagiannakopoulos, MR Bauer, SM Davidson, M Heimann, ... Cell metabolism 24 (2), 324-331, 2016 | 440 | 2016 |
Rapid modelling of cooperating genetic events in cancer through somatic genome editing FJ Sánchez-Rivera, T Papagiannakopoulos, R Romero, T Tammela, ... Nature 516 (7531), 428-431, 2014 | 424 | 2014 |
Nrf2 activation promotes lung cancer metastasis by inhibiting the degradation of Bach1 L Lignitto, SE LeBoeuf, H Homer, S Jiang, M Askenazi, TR Karakousi, ... Cell 178 (2), 316-329. e18, 2019 | 423 | 2019 |
Detained introns are a novel, widespread class of post-transcriptionally spliced introns PL Boutz, A Bhutkar, PA Sharp Genes & development 29 (1), 63-80, 2015 | 385 | 2015 |
A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma T Tammela, FJ Sanchez-Rivera, NM Cetinbas, K Wu, NS Joshi, ... Nature 545 (7654), 355-359, 2017 | 317 | 2017 |
In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis J Roper, T Tammela, NM Cetinbas, A Akkad, A Roghanian, S Rickelt, ... Nature biotechnology 35 (6), 569-576, 2017 | 310 | 2017 |
Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing DG McFadden, T Papagiannakopoulos, A Taylor-Weiner, C Stewart, ... Cell 156 (6), 1298-1311, 2014 | 294 | 2014 |
Genome-wide identification of Ago2 binding sites from mouse embryonic stem cells with and without mature microRNAs AKL Leung, AG Young, A Bhutkar, GX Zheng, AD Bosson, CB Nielsen, ... Nature structural & molecular biology 18 (2), 237-244, 2011 | 286 | 2011 |
Polytene chromosomal maps of 11 Drosophila species: the order of genomic scaffolds inferred from genetic and physical maps SW Schaeffer, A Bhutkar, BF McAllister, M Matsuda, LM Matzkin, ... Genetics 179 (3), 1601-1655, 2008 | 253 | 2008 |
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer TG Oliver, KL Mercer, LC Sayles, JR Burke, D Mendus, KS Lovejoy, ... Genes & development 24 (8), 837-852, 2010 | 242 | 2010 |
Chromosomal rearrangement inferred from comparisons of 12 Drosophila genomes A Bhutkar, SW Schaeffer, SM Russo, M Xu, TF Smith, WM Gelbart Genetics 179 (3), 1657-1680, 2008 | 241 | 2008 |
Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma DG McFadden, K Politi, A Bhutkar, FK Chen, X Song, M Pirun, ... Proceedings of the National Academy of Sciences 113 (42), E6409-E6417, 2016 | 185 | 2016 |
p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer DG McFadden, A Vernon, PM Santiago, R Martinez-McFaline, A Bhutkar, ... Proceedings of the National Academy of Sciences 111 (16), E1600-E1609, 2014 | 175 | 2014 |
Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop TG Oliver, E Meylan, GP Chang, W Xue, JR Burke, TJ Humpton, ... Molecular cell 43 (1), 57-71, 2011 | 171 | 2011 |
Survival of pancreatic cancer cells lacking KRAS function MD Muzumdar, PY Chen, KJ Dorans, KM Chung, A Bhutkar, E Hong, ... Nature communications 8 (1), 1090, 2017 | 162 | 2017 |