Serum-induced phosphorylation of the serum response factor coactivator MKL1 by the extracellular signal-regulated kinase 1/2 pathway inhibits its nuclear localization S Muehlich, R Wang, SM Lee, TC Lewis, C Dai, R Prywes Molecular and cellular biology 28 (20), 6302-6313, 2008 | 144 | 2008 |
Accuracy and completeness of drug information in Wikipedia: a comparison with standard textbooks of pharmacology J Kräenbring, T Monzon Penza, J Gutmann, S Muehlich, O Zolk, ... PloS one 9 (9), e106930, 2014 | 124 | 2014 |
TRPM7 kinase activity is essential for T cell colonization and alloreactivity in the gut A Romagnani, V Vettore, T Rezzonico-Jost, S Hampe, E Rottoli, ... Nature communications 8 (1), 1917, 2017 | 86 | 2017 |
Actin-dependent regulation of connective tissue growth factor S Muehlich, I Cicha, CD Garlichs, B Krueger, G Posern, ... American Journal of Physiology-Cell Physiology 292 (5), C1732-C1738, 2007 | 83 | 2007 |
Induction of connective tissue growth factor (CTGF) in human endothelial cells by lysophosphatidic acid, sphingosine-1-phosphate, and platelets S Muehlich, N Schneider, F Hinkmann, CD Garlichs, M Goppelt-Struebe Atherosclerosis 175 (2), 261-268, 2004 | 82 | 2004 |
Filamin A interacts with the coactivator MKL1 to promote the activity of the transcription factor SRF and cell migration P Kircher, C Hermanns, M Nossek, MK Drexler, R Grosse, M Fischer, ... Science signaling 8 (402), ra112-ra112, 2015 | 61 | 2015 |
The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1 S Muehlich, V Hampl, S Khalid, S Singer, N Frank, K Breuhahn, ... Oncogene 31 (35), 3913-3923, 2012 | 59 | 2012 |
Pharmacological inhibition of RhoA signaling prevents connective tissue growth factor induction in endothelial cells exposed to non-uniform shear stress I Cicha, M Goppelt-Struebe, S Muehlich, A Yilmaz, D Raaz, WG Daniel, ... Atherosclerosis 196 (1), 136-145, 2008 | 55 | 2008 |
Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene‐induced senescence V Hampl, C Martin, A Aigner, S Hoebel, S Singer, N Frank, A Sarikas, ... EMBO molecular medicine 5 (9), 1367-1382, 2013 | 54 | 2013 |
Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling F Scheufele, B Wolf, M Kruse, T Hartmann, J Lempart, S Mühlich, ... Cellular signalling 26 (2), 233-239, 2014 | 44 | 2014 |
Inhibition of TRPM7 blocks MRTF/SRF-dependent transcriptional and tumorigenic activity S Voringer, L Schreyer, W Nadolni, MA Meier, K Woerther, C Mittermeier, ... Oncogene 39 (11), 2328-2344, 2020 | 39 | 2020 |
The novel MKL target gene myoferlin modulates expansion and senescence of hepatocellular carcinoma C Hermanns, V Hampl, K Holzer, A Aigner, J Penkava, N Frank, DE Martin, ... Oncogene 36 (24), 3464-3476, 2017 | 33 | 2017 |
A novel inhibitory mechanism of MRTF-A/B on the ICAM-1 gene expression in vascular endothelial cells K Hayashi, T Murai, H Oikawa, T Masuda, K Kimura, S Muehlich, ... Scientific reports 5 (1), 10627, 2015 | 28 | 2015 |
Inhibition of Cullin-RING E3 ubiquitin ligase 7 by simian virus 40 large T antigen T Hartmann, X Xu, M Kronast, S Muehlich, K Meyer, W Zimmermann, ... Proceedings of the National Academy of Sciences 111 (9), 3371-3376, 2014 | 27 | 2014 |
Molecular mechanisms to target cellular senescence in hepatocellular carcinoma C Mittermeier, A Konopa, S Muehlich Cells 9 (12), 2540, 2020 | 22 | 2020 |
Serine-727 phosphorylation activates hypothalamic STAT-3 independently from tyrosine-705 phosphorylation A Breit, V Besik, HJ Solinski, S Muehlich, E Glas, SJ Yarwood, ... Molecular endocrinology 29 (3), 445-459, 2015 | 22 | 2015 |
Actin-mediated gene expression depends on RhoA and Rac1 signaling in proximal tubular epithelial cells K Giehl, C Keller, S Muehlich, M Goppelt-Struebe PloS one 10 (3), e0121589, 2015 | 18 | 2015 |
ATF2 loss promotes tumor invasion in colorectal cancer cells via upregulation of cancer driver TROP2 K Huebner, K Erlenbach-Wuensch, J Prochazka, I Sheraj, C Hampel, ... Cellular and Molecular Life Sciences 79 (8), 423, 2022 | 16 | 2022 |
Synergistic induction of CTGF by cytochalasin D and TGFβ-1 in primary human renal epithelial cells: Role of transcriptional regulators MKL1, YAP/TAZ and Smad2/3 S Muehlich, M Rehm, A Ebenau, M Goppelt-Struebe Cellular signalling 29, 31-40, 2017 | 14 | 2017 |
Unravelling a new mechanism linking actin polymerization and gene transcription S Muehlich, C Hermanns, MA Meier, P Kircher, T Gudermann Nucleus 7 (2), 121-125, 2016 | 14 | 2016 |