The multifaceted roles of PARP1 in DNA repair and chromatin remodelling A Ray Chaudhuri, A Nussenzweig Nature reviews Molecular cell biology 18 (10), 610-621, 2017 | 1309 | 2017 |
Replication fork stability confers chemoresistance in BRCA-deficient cells A Ray Chaudhuri, E Callen, X Ding, E Gogola, AA Duarte, JE Lee, ... Nature 535 (7612), 382-387, 2016 | 819 | 2016 |
Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis Y Hashimoto, A Ray Chaudhuri, M Lopes, V Costanzo Nature structural & molecular biology 17 (11), 1305-1311, 2010 | 570 | 2010 |
Topoisomerase I poisoning results in PARP-mediated replication fork reversal A Ray Chaudhuri, Y Hashimoto, R Herrador, KJ Neelsen, D Fachinetti, ... Nature structural & molecular biology 19 (4), 417-423, 2012 | 503 | 2012 |
Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition M Berti, A Ray Chaudhuri, S Thangavel, S Gomathinayagam, S Kenig, ... Nature structural & molecular biology 20 (3), 347-354, 2013 | 450 | 2013 |
Replication fork reversal triggers fork degradation in BRCA2-defective cells S Mijic, R Zellweger, N Chappidi, M Berti, K Jacobs, K Mutreja, S Ursich, ... Nature communications 8 (1), 859, 2017 | 342 | 2017 |
Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies X Ding, AR Chaudhuri, E Callen, Y Pang, K Biswas, KD Klarmann, ... Nature communications 7 (1), 12425, 2016 | 138 | 2016 |
RIF1 promotes replication fork protection and efficient restart to maintain genome stability C Mukherjee, V Tripathi, EM Manolika, AM Heijink, G Ricci, S Merzouk, ... Nature communications 10 (1), 3287, 2019 | 104 | 2019 |
Deregulated origin licensing leads to chromosomal breaks by rereplication of a gapped DNA template KJ Neelsen, IMY Zanini, S Mijic, R Herrador, R Zellweger, AR Chaudhuri, ... Genes & development 27 (23), 2537-2542, 2013 | 102 | 2013 |
BRCA1 haploinsufficiency is masked by RNF168-mediated chromatin ubiquitylation D Zong, S Adam, Y Wang, H Sasanuma, E Callén, M Murga, A Day, ... Molecular cell 73 (6), 1267-1281. e7, 2019 | 86 | 2019 |
Visualization and interpretation of eukaryotic DNA replication intermediates in vivo by electron microscopy KJ Neelsen, AR Chaudhuri, C Follonier, R Herrador, M Lopes Functional analysis of DNA and chromatin, 177-208, 2014 | 64 | 2014 |
Poly (ADP-ribosyl) glycohydrolase prevents the accumulation of unusual replication structures during unperturbed S phase AR Chaudhuri, AK Ahuja, R Herrador, M Lopes Molecular and cellular biology, 2015 | 58 | 2015 |
Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps MP Dias, V Tripathi, I van der Heijden, K Cong, EM Manolika, J Bhin, ... Molecular cell 81 (22), 4692-4708. e9, 2021 | 52 | 2021 |
Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability ME Geijer, D Zhou, K Selvam, B Steurer, C Mukherjee, B Evers, S Cugusi, ... Nature cell biology 23 (6), 608-619, 2021 | 51 | 2021 |
Atypical G protein β5 promotes cardiac oxidative stress, apoptosis, and fibrotic remodeling in response to multiple cancer chemotherapeutics S Chakraborti, A Pramanick, S Saha, SS Roy, AR Chaudhuri, M Das, ... Cancer Research 78 (2), 528-541, 2018 | 24 | 2018 |
Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51 AM Heijink, C Stok, D Porubsky, EM Manolika, JK de Kanter, YP Kok, ... Nature Communications 13 (1), 6722, 2022 | 20 | 2022 |
SMARCAD1-mediated active replication fork stability maintains genome integrity CSY Lo, M van Toorn, V Gaggioli, M Paes Dias, Y Zhu, EM Manolika, ... Science Advances 7 (19), eabe7804, 2021 | 20 | 2021 |
More end resection is not merrier D Zong, A Ray Chaudhuri, A Nussenzweig Nature structural & molecular biology 23 (8), 699-701, 2016 | 13 | 2016 |
A BRCA1 coiled-coil domain variant disrupting PALB2 interaction promotes the development of mammary tumors and confers a targetable defect in homologous recombination repair EM Pulver, C Mukherjee, G van de Kamp, SJ Roobol, MB Rother, ... Cancer research 81 (24), 6171-6182, 2021 | 8 | 2021 |
Sister chromatid exchanges induced by perturbed replication are formed independently of homologous recombination factors AM Heijink, C Stok, D Porubsky, EM Manolika, YP Kok, M Everts, ... Biorxiv, 2021.09. 17.460736, 2021 | 4 | 2021 |