Jeffrey McArthur
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Structure/function characterization of μ-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels
MM Zhang, BR Green, P Catlin, B Fiedler, L Azam, A Chadwick, H Terlau, ...
Journal of Biological Chemistry 282 (42), 30699-30706, 2007
Marine toxins that target voltage-gated sodium channels
A Al-Sabi, J McArthur, V Ostroumov, RJ French
Marine Drugs 4 (3), 157-192, 2006
Dicarba α-Conotoxin Vc1.1 Analogues with Differential Selectivity for Nicotinic Acetylcholine and GABAB Receptors
BJ Van Lierop, SD Robinson, SN Kompella, A Belgi, JR McArthur, A Hung, ...
ACS chemical biology 8 (8), 1815-1821, 2013
Unexpected synergism between tetrodotoxin and μ-conotoxin in blocking voltage-gated sodium channels
MM Zhang, JR McArthur, L Azam, G Bulaj, BM Olivera, RJ French, ...
Channels 3 (1), 32-38, 2009
Conotoxins targeting neuronal voltage-gated sodium channel subtypes: potential analgesics?
O Knapp, JR McArthur, DJ Adams
Toxins 4 (11), 1236-1260, 2012
Interactions of key charged residues contributing to selective block of neuronal sodium channels by μ-conotoxin KIIIA
JR McArthur, G Singh, D McMaster, R Winkfein, DP Tieleman, RJ French
Molecular pharmacology 80 (4), 573-584, 2011
Modulation of KvAP unitary conductance and gating by 1-alkanols and other surface active agents
RK Finol-Urdaneta, JR McArthur, PF Juranka, RJ French, CE Morris
Biophysical journal 98 (5), 762-772, 2010
Differential Cav2.1 and Cav2.3 channel inhibition by baclofen and α-conotoxin Vc1.1 via GABAB receptor activation
G Berecki, JR McArthur, H Cuny, RJ Clark, DJ Adams
Journal of General Physiology 143 (4), 465-479, 2014
Multiple, distributed interactions of μ-conotoxin PIIIA associated with broad targeting among voltage-gated sodium channels
JR McArthur, V Ostroumov, A Al-Sabi, D McMaster, RJ French
Biochemistry 50 (1), 116-124, 2011
Orientation of μ-conotoxin PIIIA in a sodium channel vestibule, based on voltage dependence of its binding
JR McArthur, G Singh, ML O'Mara, D McMaster, V Ostroumov, ...
Molecular pharmacology 80 (2), 219-227, 2011
Analgesic conopeptides targeting G protein-coupled receptors reduce excitability of sensory neurons
M Sadeghi, JR McArthur, RK Finol-Urdaneta, DJ Adams
Neuropharmacology 127, 116-123, 2017
ω-Conotoxin GVIA mimetics that bind and inhibit neuronal Cav2. 2 ion channels
CE Tranberg, A Yang, I Vetter, JR McArthur, JB Baell, RJ Lewis, KL Tuck, ...
Marine drugs 10 (10), 2349-2368, 2012
Marine toxins targeting KV1 channels: Pharmacological tools and therapeutic scaffolds
RK Finol-Urdaneta, A Belovanovic, M Micic-Vicovac, GK Kinsella, ...
Marine drugs 18 (3), 173, 2020
Batrachotoxin acts as a stent to hold open homotetrameric prokaryotic voltage-gated sodium channels
RK Finol-Urdaneta, JR McArthur, MP Goldschen-Ohm, R Gaudet, ...
Journal of General Physiology 151 (2), 186-199, 2019
Extremely potent block of bacterial voltage-gated sodium channels by µ-conotoxin PIIIA
RK Finol-Urdaneta, JR McArthur, VS Korkosh, S Huang, D McMaster, ...
Marine drugs 17 (9), 510, 2019
Analgesic transient receptor potential vanilloid‐1‐active compounds inhibit native and recombinant T‐type calcium channels
JR McArthur, RK Finol‐Urdaneta, DJ Adams
British journal of pharmacology 176 (13), 2264-2278, 2019
Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides
SR Sousa, JR McArthur, A Brust, RF Bhola, KJ Rosengren, L Ragnarsson, ...
Scientific reports 8 (1), 1-15, 2018
Polymodal, high affinity actions of μ-conotoxins on a bacterial voltage-gated sodium channel
RK Finol-Urdaneta, R Glavica, JR McArthur, RJ French
Biophysical Journal 104 (2), 136a-137a, 2013
Trans-channel interactions in batrachotoxin-modified skeletal muscle sodium channels: Voltage-dependent block by cytoplasmic amines, and the influence of μ-conotoxin GIIIA …
E Pavlov, T Britvina, JR McArthur, Q Ma, I Sierralta, GW Zamponi, ...
Biophysical journal 95 (9), 4277-4288, 2008
An attempt to determine the orientation of mu-conotoxin binding to sodium channels by mapping the contributions of individual residues to the voltage dependence of block
JR McArthur, RJ French
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