| An orally available non-nucleotide STING agonist with antitumor activity BS Pan, SA Perera, JA Piesvaux, JP Presland, GK Schroeder, ... Science 369 (6506), 2020 | 332 | 2020 |
| Chiral Brønsted acid-catalyzed enantioselective α-hydroxylation of β-dicarbonyl compounds M Lu, D Zhu, Y Lu, X Zeng, B Tan, Z Xu, G Zhong Journal of the American Chemical Society 131 (13), 4562-4563, 2009 | 174 | 2009 |
| Organocatalytic Asymmetric α‐Aminoxylation/Aza‐Michael Reactions for the Synthesis of Functionalized Tetrahydro‐1, 2‐oxazines M Lu, D Zhu, Y Lu, Y Hou, B Tan, G Zhong Angewandte Chemie 120 (52), 10341-10345, 2008 | 155 | 2008 |
| Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio) diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G … KC Nicolaou, M Lu, S Totokotsopoulos, P Heretsch, D Giguère, YP Sun, ... Journal of the American Chemical Society 134 (41), 17320-17332, 2012 | 128 | 2012 |
| A Highly Diastereo-and Enantioselective Synthesis of Multisubstituted Cyclopentanes with Four Chiral Carbons by the Organocatalytic Domino Michael− Henry Reaction B Tan, PJ Chua, X Zeng, M Lu, G Zhong Organic letters 10 (16), 3489-3492, 2008 | 113 | 2008 |
| Highly Efficient Asymmetric Trans-Selective Aziridination of Diazoacetamides and N-Boc-imines Catalyzed by Chiral Brønsted Acids X Zeng, X Zeng, Z Xu, M Lu, G Zhong Organic letters 11 (14), 3036-3039, 2009 | 102 | 2009 |
| A highly stereoselective organocatalytic tandem aminoxylation/aza-Michael reaction for the synthesis of tetrahydro-1, 2-oxazines D Zhu, M Lu, PJ Chua, B Tan, F Wang, X Yang, G Zhong Organic letters 10 (20), 4585-4588, 2008 | 83 | 2008 |
| Streamlined Total Synthesis of Uncialamycin and Its Application to the Synthesis of Designed Analogues for Biological Investigations KC Nicolaou, Y Wang, M Lu, D Mandal, MR Pattanayak, R Yu, AA Shah, ... Journal of the American Chemical Society, 2016 | 81 | 2016 |
| Catalytic Asymmetric Formal [4+ 1] Annulation Leading to Optically Active cis-Isoxazoline N-Oxides Z Shi, B Tan, WWY Leong, X Zeng, M Lu, G Zhong Organic letters 12 (23), 5402-5405, 2010 | 63 | 2010 |
| Chiral Brønsted Acid Catalyzed Enantioselective α‐Aminoxylation of Enecarbamates M Lu, Y Lu, D Zhu, X Zeng, X Li, G Zhong Angewandte Chemie International Edition 49 (46), 8588-8592, 2010 | 62 | 2010 |
| Chiral Brønsted Acid Catalyzed Enantioselective Addition of α-Isocyanoacetamides to Aldehydes X Zeng, K Ye, M Lu, PJ Chua, B Tan, G Zhong Organic letters 12 (10), 2414-2417, 2010 | 48 | 2010 |
| Highly Stereoselective One‐Pot Synthesis of Bicyclic Isoxazolidines with Five Stereogenic Centers by an Organocatalytic Process D Zhu, M Lu, L Dai, G Zhong Angewandte Chemie International Edition 48 (33), 6089-6092, 2009 | 41 | 2009 |
| Total Synthesis of Myceliothermophins C, D, and E KC Nicolaou, L Shi, M Lu, MR Pattanayak, AA Shah, HA Ioannidou, ... Angewandte Chemie International Edition 53 (41), 10970-10974, 2014 | 39 | 2014 |
| General Synthetic Approach to Functionalized Dihydrooxepines KC Nicolaou, R Yu, L Shi, Q Cai, M Lu, P Heretsch Organic letters 15 (8), 1994-1997, 2013 | 33 | 2013 |
| Practical Synthesis of p‐and o‐Amino‐and Methoxyphenolic Anthraquinones KC Nicolaou, M Lu, P Chen, AA Shah Angewandte Chemie International Edition 54 (43), 12687-12691, 2015 | 20 | 2015 |
| Benzo [b] thiophene compounds as sting agonists MD Altman, BD Cash, W Chang, JN Cumming, AM Haidle, TJ Henderson, ... US Patent 10,414,747, 2019 | 17 | 2019 |
| Highly Enantioselective Synthesis of Fluorinated β-Amino Ketones via Asymmetric Organocatalytic Mannich Reactions: A Case Study of Unusual Reversal of Regioselectivity M Lu, Y Lu, PKA Tan, QY Lau, G Zhong Synlett 2011 (04), 477-480, 2011 | 14 | 2011 |
| Structure-Based Discovery of Proline-Derived Arginase Inhibitors with Improved Oral Bioavailability for Immuno-Oncology M Lu, H Zhang, D Li, M Childers, Q Pu, RL Palte, S Gathiaka, TW Lyons, ... ACS Medicinal Chemistry Letters, 2021 | 13 | 2021 |
| Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors D Li, H Zhang, TW Lyons, M Lu, A Achab, Q Pu, M Childers, ... ACS Medicinal Chemistry Letters, 2021 | 8 | 2021 |
| Cyclic di-nucleotide compounds as sting agonists MD Altman, B Andresen, W Chang, ML Childers, JN Cumming, AM Haidle, ... US Patent 10,766,919, 2020 | 5 | 2020 |
