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Franz-Josef Meyer-Almes
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Dual-color fluorescence cross-correlation spectroscopy for multicomponent diffusional analysis in solution
P Schwille, FJ Meyer-Almes, R Rigler
Biophysical journal 72 (4), 1878-1886, 1997
11191997
Mechanism of intercalation into the DNA double helix by ethidium
FJ Meyer-Almes, D Porschke
Biochemistry 32 (16), 4246-4253, 1993
3211993
Fluorescence cross-correlation: a new concept for polymerase chain reaction
R Rigler, Z Földes-Papp, FJ Meyer-Almes, C Sammet, M Völcker, ...
Journal of biotechnology 63 (2), 97-109, 1998
1811998
Fluorescence correlation spectroscopy: lead discovery by miniaturized HTS
M Auer, KJ Moore, FJ Meyer-Almes, R Guenther, AJ Pope, KA Stoeckli
Drug Discovery Today 3 (10), 457-465, 1998
1491998
Thailandepsins: bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities
C Wang, LM Henkes, LB Doughty, M He, D Wang, FJ Meyer-Almes, ...
Journal of natural products 74 (10), 2031-2038, 2011
1392011
Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets
MGJ Baud, T Leiser, P Haus, S Samlal, AC Wong, RJ Wood, V Petrucci, ...
Journal of medicinal chemistry 55 (4), 1731-1750, 2012
1042012
Toward photopharmacological antimicrobial chemotherapy using photoswitchable amidohydrolase inhibitors
CE Weston, A Krämer, F Colin, O Yildiz, MGJ Baud, FJ Meyer-Almes, ...
ACS Infectious Diseases 3 (2), 152-161, 2017
842017
The proapoptotic influenza A virus protein PB1-F2 forms a nonselective ion channel
M Henkel, D Mitzner, P Henklein, FJ Meyer-Almes, A Moroni, ...
PLoS One 5 (6), e11112, 2010
742010
Repurposing approved drugs as potential inhibitors of 3CL-protease of SARS-CoV-2: Virtual screening and structure based drug design
FJ Meyer-Almes
Computational Biology and Chemistry 88, 107351, 2020
642020
A novel and robust homogeneous fluorescence-based assay using nanoparticles for pharmaceutical screening and diagnostics
S Schaertl, FJ Meyer-Almes, E Lopez-Calle, A Siemers, J Kramer
SLAS Discovery 5 (4), 227-237, 2000
532000
Enzyme Inhibition Assays Using Fluorescence Correlation Spectroscopy: A New Algorithm for the Derivation of k cat/KM and K i Values at Substrate Concentrations Much Lower than …
FJ Meyer-Almes, M Auer
Biochemistry 39 (43), 13261-13268, 2000
502000
Class IIa HDACs repressive activities on MEF2‐depedent transcription are associated with poor prognosis of ER+ breast tumors
A Clocchiatti, E Di Giorgio, S Ingrao, FJ Meyer‐Almes, C Tripodo, ...
The FASEB Journal 27 (3), 942-954, 2013
482013
Histone deacetylase inhibitor assay based on fluorescence resonance energy transfer
D Riester, C Hildmann, A Schwienhorst, FJ Meyer-Almes
Analytical biochemistry 362 (1), 136-141, 2007
382007
Discovery of novel N-substituted thiazolidinediones (TZDs) as HDAC8 inhibitors: in-silico studies, synthesis, and biological evaluation
N Upadhyay, K Tilekar, N Jänsch, M Schweipert, JD Hess, LH Macias, ...
Bioorganic chemistry 100, 103934, 2020
362020
Discovery of 5-naphthylidene-2, 4-thiazolidinedione derivatives as selective HDAC8 inhibitors and evaluation of their cytotoxic effects in leukemic cell lines
K Tilekar, N Upadhyay, N Jänsch, M Schweipert, P Mrowka, ...
Bioorganic chemistry 95, 103522, 2020
362020
The enzyme activity of histone deacetylase 8 is modulated by a redox-switch
N Jänsch, C Meyners, M Muth, A Kopranovic, O Witt, I Oehme, ...
Redox Biology 20, 60-67, 2019
352019
Identification of novel small-molecule histone deacetylase inhibitors by medium-throughput screening using a fluorigenic assay
D Wegener, C Hildmann, D Riester, A Schober, FJ Meyer-Almes, ...
Biochemical Journal 413 (1), 143-150, 2008
352008
Identification of novel small-molecule histone deacetylase inhibitors by medium-throughput screening using a fluorigenic assay
D Wegener, C Hildmann, D Riester, A Schober, FJ Meyer-Almes, ...
Biochemical Journal 413 (1), 143-150, 2008
352008
Thioester derivatives of the natural product psammaplin A as potent histone deacetylase inhibitors
MGJ Baud, T Leiser, V Petrucci, M Gunaratnam, S Neidle, ...
Beilstein Journal of Organic Chemistry 9 (1), 81-88, 2013
332013
Pharmacophore hybridization approach to discover novel pyrazoline-based hydantoin analogs with anti-tumor efficacy
N Upadhyay, K Tilekar, F Loiodice, NY Anisimova, TS Spirina, ...
Bioorganic Chemistry 107, 104527, 2021
302021
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