| Role of dietary fructose and hepatic de novo lipogenesis in fatty liver disease S Softic, DE Cohen, CR Kahn Digestive diseases and sciences 61, 1282-1293, 2016 | 648 | 2016 |
| Interactions between gut microbiota, host genetics and diet modulate the predisposition to obesity and metabolic syndrome S Ussar, NW Griffin, O Bezy, S Fujisaka, S Vienberg, S Softic, L Deng, ... Cell metabolism 22 (3), 516-530, 2015 | 570 | 2015 |
| High‐fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis R Kohli, M Kirby, SA Xanthakos, S Softic, AE Feldstein, V Saxena, ... Hepatology 52 (3), 934-944, 2010 | 437 | 2010 |
| Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway CL Karp, LM Flick, KW Park, S Softic, TM Greer, R Keledjian, R Yang, ... Nature immunology 5 (4), 388-392, 2004 | 417 | 2004 |
| Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling S Softic, MK Gupta, GX Wang, S Fujisaka, BT O’Neill, TN Rao, ... The Journal of clinical investigation 127 (11), 4059-4074, 2017 | 303 | 2017 |
| IL‐17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice ITW Harley, TE Stankiewicz, DA Giles, S Softic, LM Flick, M Cappelletti, ... Hepatology 59 (5), 1830-1839, 2014 | 259 | 2014 |
| Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling DA Giles, ME Moreno-Fernandez, TE Stankiewicz, S Graspeuntner, ... Nature medicine 23 (7), 829-838, 2017 | 219 | 2017 |
| Dietary sugars alter hepatic fatty acid oxidation via transcriptional and post-translational modifications of mitochondrial proteins S Softic, JG Meyer, GX Wang, MK Gupta, TM Batista, HPMM Lauritzen, ... Cell metabolism 30 (4), 735-753. e4, 2019 | 169 | 2019 |
| Antibiotic effects on gut microbiota and metabolism are host dependent S Fujisaka, S Ussar, C Clish, S Devkota, JM Dreyfuss, M Sakaguchi, ... The Journal of clinical investigation 126 (12), 4430-4443, 2016 | 164 | 2016 |
| Fructose and hepatic insulin resistance S Softic, KL Stanhope, J Boucher, S Divanovic, MA Lanaspa, RJ Johnson, ... Critical reviews in clinical laboratory sciences 57 (5), 308-322, 2020 | 161 | 2020 |
| Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis BT O’Neill, KY Lee, K Klaus, S Softic, MT Krumpoch, J Fentz, KI Stanford, ... The Journal of clinical investigation 126 (9), 3433-3446, 2016 | 146 | 2016 |
| Regulation of UCP1 and mitochondrial metabolism in brown adipose tissue by reversible succinylation GX Wang, JG Meyer, W Cai, S Softic, ME Li, E Verdin, C Newgard, ... Molecular cell 74 (4), 844-857. e7, 2019 | 140 | 2019 |
| Differential roles of insulin and IGF-1 receptors in adipose tissue development and function J Boucher, S Softic, A El Ouaamari, MT Krumpoch, A Kleinridders, ... Diabetes 65 (8), 2201-2213, 2016 | 136 | 2016 |
| Hepatic natural killer T‐cell and CD8+ T‐cell signatures in mice with nonalcoholic steatohepatitis J Bhattacharjee, M Kirby, S Softic, L Miles, RM Salazar‐Gonzalez, ... Hepatology communications 1 (4), 299-310, 2017 | 128 | 2017 |
| Lipodystrophy due to adipose tissue–specific insulin receptor knockout results in progressive NAFLD S Softic, J Boucher, MH Solheim, S Fujisaka, MF Haering, EP Homan, ... Diabetes 65 (8), 2187-2200, 2016 | 112 | 2016 |
| Hepatocyte stress increases expression of yes‐associated protein and transcriptional coactivator with PDZ‐binding motif in hepatocytes to promote parenchymal inflammation and … M Mooring, BH Fowl, SZC Lum, YE Liu, K Yao, S Softic, R Kirchner, ... Hepatology 71 (5), 1813-1830, 2020 | 110 | 2020 |
| Evolving role for pharmacotherapy in NAFLD/NASH SL Attia, S Softic, M Mouzaki Clinical and translational science 14 (1), 11-19, 2021 | 101 | 2021 |
| Subcutaneous adipose tissue transplantation in diet‐induced obese mice attenuates metabolic dysregulation while removal exacerbates it MT Foster, S Softic, J Caldwell, R Kohli, AD deKloet, RJ Seeley Physiological reports 1 (2), 2013 | 97 | 2013 |
| Transplantation of non-visceral fat to the visceral cavity improves glucose tolerance in mice: investigation of hepatic lipids and insulin sensitivity MT Foster, H Shi, S Softic, R Kohli, RJ Seeley, SC Woods Diabetologia 54, 2890-2899, 2011 | 60 | 2011 |
| Tissue-specific fructose metabolism in obesity and diabetes RN Helsley, F Moreau, MK Gupta, A Radulescu, B DeBosch, S Softic Current diabetes reports 20, 1-16, 2020 | 47 | 2020 |
C. Ronald KahnJoslin Diabetes Center and Harvard Medical SchoolVerified email at joslin.harvard.edu
