| A vicious cycle of β amyloid–dependent neuronal hyperactivation B Zott, MM Simon, W Hong, F Unger, HJ Chen-Engerer, MP Frosch, ... Science 365 (6453), 559-565, 2019 | 466 | 2019 |
| Dual‐pH sensitive charge‐reversal polypeptide micelles for tumor‐triggered targeting uptake and nuclear drug delivery SS Han, ZY Li, JY Zhu, K Han, ZY Zeng, W Hong, WX Li, HZ Jia, Y Liu, ... Small 11 (21), 2543-2554, 2015 | 257 | 2015 |
| The genome of Mesobuthus martensii reveals a unique adaptation model of arthropods Z Cao, Y Yu, Y Wu, P Hao, Z Di, Y He, Z Chen, W Yang, Z Shen, X He, ... Nature communications 4 (1), 2602, 2013 | 243 | 2013 |
| Virucidal activity of a scorpion venom peptide variant mucroporin-M1 against measles, SARS-CoV and influenza H5N1 viruses Q Li, Z Zhao, D Zhou, Y Chen, W Hong, L Cao, J Yang, Y Zhang, W Shi, ... Peptides 32 (7), 1518-1525, 2011 | 142 | 2011 |
| Human brain-derived Aβ oligomers bind to synapses and disrupt synaptic activity in a manner that requires APP Z Wang, RJ Jackson, W Hong, TM Walter, A Moreno, W Liu, S Li, ... Journal of Neuroscience, 2017 | 136 | 2017 |
| PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins GT Corbett, Z Wang, W Hong, M Colom-Cadena, J Rose, M Liao, A Asfaw, ... Acta neuropathologica 139, 503-526, 2020 | 131 | 2020 |
| Diffusible, highly bioactive oligomers represent a critical minority of soluble Aβ in Alzheimer’s disease brain W Hong, Z Wang, W Liu, TT O’Malley, M Jin, M Willem, C Haass, ... Acta neuropathologica 136, 19-40, 2018 | 118 | 2018 |
| Identification of neurotoxic cross-linked amyloid-β dimers in the Alzheimer’s brain G Brinkmalm, W Hong, Z Wang, W Liu, TT O’Malley, X Sun, MP Frosch, ... Brain 142 (5), 1441-1457, 2019 | 90 | 2019 |
| A new natural α-helical peptide from the venom of the scorpion Heterometrus petersii kills HCV R Yan, Z Zhao, Y He, L Wu, D Cai, W Hong, Y Wu, Z Cao, C Zheng, W Li Peptides 32 (1), 11-19, 2011 | 90 | 2011 |
| Cellular prion protein mediates the disruption of hippocampal synaptic plasticity by soluble tau in vivo T Ondrejcak, I Klyubin, GT Corbett, G Fraser, W Hong, AJ Mably, ... Journal of Neuroscience 38 (50), 10595-10606, 2018 | 87 | 2018 |
| Inhibitory activity and mechanism of two scorpion venom peptides against herpes simplex virus type 1 W Hong, T Li, Y Song, R Zhang, Z Zeng, S Han, X Zhang, Y Wu, W Li, ... Antiviral research 102, 1-10, 2014 | 76 | 2014 |
| Mucroporin-M1 inhibits hepatitis B virus replication by activating the mitogen-activated protein kinase (MAPK) pathway and down-regulating HNF4α in vitro and in vivo Z Zhao, W Hong, Z Zeng, Y Wu, K Hu, X Tian, W Li, Z Cao Journal of Biological Chemistry 287 (36), 30181-30190, 2012 | 74 | 2012 |
| Molecular diversity of Chaerilidae venom peptides reveals the dynamic evolution of scorpion venom components from Buthidae to non-Buthidae Y He, R Zhao, Z Di, Z Li, X Xu, W Hong, Y Wu, H Zhao, W Li, Z Cao Journal of proteomics 89, 1-14, 2013 | 66 | 2013 |
| An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer’s disease M Jin, B O’Nuallain, W Hong, J Boyd, VN Lagomarsino, TT O’Malley, ... Nature communications 9 (1), 2676, 2018 | 58 | 2018 |
| A Tat-conjugated peptide nucleic acid Tat-PNA-DR inhibits hepatitis B virus replication in vitro and in vivo by targeting LTR direct repeats of HBV RNA Z Zeng, S Han, W Hong, Y Lang, F Li, Y Liu, Z Li, Y Wu, W Li, X Zhang, ... Molecular Therapy-Nucleic Acids 5, 2016 | 44 | 2016 |
| Design of histidine-rich peptides with enhanced bioavailability and inhibitory activity against hepatitis C virus W Hong, R Zhang, Z Di, Y He, Z Zhao, J Hu, Y Wu, W Li, Z Cao Biomaterials 34 (13), 3511-3522, 2013 | 35 | 2013 |
| Histidine-rich Modification of a Scorpion-derived Peptide Improves Bioavailability and Inhibitory Activity against HSV-1 Z Zeng, R Zhang, W Hong, Y Cheng, H Wang, Y Lang, Z Ji, Y Wu, W Li, ... Theranostics 8 (1), 199-211, 2018 | 33 | 2018 |
| Mitochondrial dysfunction triggers the pathogenesis of Parkinson’s disease in neuronal C/EBPβ transgenic mice EH Ahn, K Lei, SS Kang, ZH Wang, X Liu, W Hong, YT Wang, ... Molecular Psychiatry 26 (12), 7838-7850, 2021 | 28 | 2021 |
| A Scorpion Defensin BmKDfsin4 Inhibits Hepatitis B Virus Replication in Vitro Z Zeng, Q Zhang, W Hong, Y Xie, Y Liu, W Li, Y Wu, Z Cao Toxins 8 (5), 124, 2016 | 25 | 2016 |
| Sj7170, a unique dual-function peptide with a specific α-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom Y Song, K Gong, H Yan, W Hong, L Wang, Y Wu, W Li, W Li, Z Cao Journal of Biological Chemistry 289 (17), 11667-11680, 2014 | 16 | 2014 |
Matthew P. FroschMassachusetts General Hospital & Harvard Medical SchoolVerified email at mgh.harvard.edu
