Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia J Grembecka, S He, A Shi, T Purohit, AG Muntean, RJ Sorenson, ... Nature chemical biology 8 (3), 277-284, 2012 | 422 | 2012 |
Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo D Borkin, S He, H Miao, K Kempinska, J Pollock, J Chase, T Purohit, ... Cancer cell 27 (4), 589-602, 2015 | 353 | 2015 |
Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia A Shi, MJ Murai, S He, G Lund, T Hartley, T Purohit, G Reddy, M Chruszcz, ... Blood, The Journal of the American Society of Hematology 120 (23), 4461-4469, 2012 | 207 | 2012 |
High-affinity small-molecule inhibitors of the menin-mixed lineage leukemia (MLL) interaction closely mimic a natural protein–protein interaction S He, TJ Senter, J Pollock, C Han, SK Upadhyay, T Purohit, RD Gogliotti, ... Journal of medicinal chemistry 57 (4), 1543-1556, 2014 | 111 | 2014 |
BMI1 regulates PRC1 architecture and activity through homo-and hetero-oligomerization F Gray, HJ Cho, S Shukla, S He, A Harris, B Boytsov, Ł Jaremko, ... Nature communications 7 (1), 13343, 2016 | 70 | 2016 |
Menin-MLL inhibitors block oncogenic transformation by MLL-fusion proteins in a fusion partner-independent manner S He, B Malik, D Borkin, H Miao, S Shukla, K Kempinska, T Purohit, ... Leukemia 30 (2), 508-513, 2016 | 47 | 2016 |
Stat3 promotes the development of erythroleukemia by inducing Pu. 1 expression and inhibiting erythroid differentiation S Hegde, S Ni, S He, D Yoon, GS Feng, SS Watowich, RF Paulson, ... Oncogene 28 (38), 3349-3359, 2009 | 41 | 2009 |
The same site on the integrase-binding domain of lens epithelium–derived growth factor is a therapeutic target for MLL leukemia and HIV MJ Murai, J Pollock, S He, H Miao, T Purohit, A Yokom, JL Hess, ... Blood, The Journal of the American Society of Hematology 124 (25), 3730-3737, 2014 | 35 | 2014 |
Differential modulation of the androgen receptor for prostate cancer therapy depends on the DNA response element S Kregel, P Bagamasbad, S He, E LaPensee, Y Raji, M Brogley, ... Nucleic acids research 48 (9), 4741-4755, 2020 | 25 | 2020 |
Activation of the N-terminally truncated form of the Stk receptor tyrosine kinase Sf-Stk by Friend virus-encoded gp55 is mediated by cysteine residues in the ecotropic domain … S He, S Ni, S Hegde, X Wang, DR Sharda, A August, RF Paulson, ... Journal of virology 84 (5), 2223-2235, 2010 | 16 | 2010 |
Expression of the Full Length preS Gene of Hepatitis B virus in Pichia pastoris SUN Ming-hao, YE Lin-bai, GAO Jin-rong, HE Shi-han, WU Zheng-hui VIROLOGICA SINICA 18 (2), 99-103, 2003 | 4* | 2003 |
Study on the Heredity Stability of a Recombinant Plasmid pQE30tPAr in E.coli JM109 HE Shihan, LI Baozong, ZUO Jinrong, YE Linbai, Z Yongxun, ... JOURNAL OF WUHAN UNIVERSITY(NATURAL SCIENCE EDITION) 49 (4), 497-500, 2003 | 4* | 2003 |