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Shihan He
Shihan He
QIAGEN
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Year
Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia
J Grembecka, S He, A Shi, T Purohit, AG Muntean, RJ Sorenson, ...
Nature chemical biology 8 (3), 277-284, 2012
4192012
Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo
D Borkin, S He, H Miao, K Kempinska, J Pollock, J Chase, T Purohit, ...
Cancer cell 27 (4), 589-602, 2015
3502015
Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia
A Shi, MJ Murai, S He, G Lund, T Hartley, T Purohit, G Reddy, M Chruszcz, ...
Blood, The Journal of the American Society of Hematology 120 (23), 4461-4469, 2012
2052012
High-affinity small-molecule inhibitors of the menin-mixed lineage leukemia (MLL) interaction closely mimic a natural protein–protein interaction
S He, TJ Senter, J Pollock, C Han, SK Upadhyay, T Purohit, RD Gogliotti, ...
Journal of medicinal chemistry 57 (4), 1543-1556, 2014
1092014
BMI1 regulates PRC1 architecture and activity through homo-and hetero-oligomerization
F Gray, HJ Cho, S Shukla, S He, A Harris, B Boytsov, Ł Jaremko, ...
Nature communications 7 (1), 13343, 2016
672016
Menin-MLL inhibitors block oncogenic transformation by MLL-fusion proteins in a fusion partner-independent manner
S He, B Malik, D Borkin, H Miao, S Shukla, K Kempinska, T Purohit, ...
Leukemia 30 (2), 508-513, 2016
472016
Stat3 promotes the development of erythroleukemia by inducing Pu. 1 expression and inhibiting erythroid differentiation
S Hegde, S Ni, S He, D Yoon, GS Feng, SS Watowich, RF Paulson, ...
Oncogene 28 (38), 3349-3359, 2009
412009
The same site on the integrase-binding domain of lens epithelium–derived growth factor is a therapeutic target for MLL leukemia and HIV
MJ Murai, J Pollock, S He, H Miao, T Purohit, A Yokom, JL Hess, ...
Blood, The Journal of the American Society of Hematology 124 (25), 3730-3737, 2014
352014
Differential modulation of the androgen receptor for prostate cancer therapy depends on the DNA response element
S Kregel, P Bagamasbad, S He, E LaPensee, Y Raji, M Brogley, ...
Nucleic acids research 48 (9), 4741-4755, 2020
242020
Activation of the N-terminally truncated form of the Stk receptor tyrosine kinase Sf-Stk by Friend virus-encoded gp55 is mediated by cysteine residues in the ecotropic domain …
S He, S Ni, S Hegde, X Wang, DR Sharda, A August, RF Paulson, ...
Journal of virology 84 (5), 2223-2235, 2010
162010
Expression of the Full Length preS Gene of Hepatitis B virus in Pichia pastoris
SUN Ming-hao, YE Lin-bai, GAO Jin-rong, HE Shi-han, WU Zheng-hui
VIROLOGICA SINICA 18 (2), 99-103, 2003
4*2003
Study on the Heredity Stability of a Recombinant Plasmid pQE30tPAr in E.coli JM109
HE Shihan, LI Baozong, ZUO Jinrong, YE Linbai, Z Yongxun, ...
JOURNAL OF WUHAN UNIVERSITY(NATURAL SCIENCE EDITION) 49 (4), 497-500, 2003
4*2003
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