Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels DL Capes, MP Goldschen-Ohm, M Arcisio-Miranda, F Bezanilla, ... Journal of General Physiology 142 (2), 101-112, 2013 | 211 | 2013 |
Multiple pore conformations driven by asynchronous movements of voltage sensors in a eukaryotic sodium channel MP Goldschen-Ohm, DL Capes, KM Oelstrom, B Chanda Nature communications 4 (1), 1350, 2013 | 97 | 2013 |
Exocytotic fusion pores are composed of both lipids and proteins H Bao, M Goldschen-Ohm, P Jeggle, B Chanda, JM Edwardson, ... Nature structural & molecular biology 23 (1), 67-73, 2016 | 87 | 2016 |
Observing Single‐Molecule Dynamics at Millimolar Concentrations MP Goldschen‐Ohm, DS White, VA Klenchin, B Chanda, RH Goldsmith Angewandte Chemie 129 (9), 2439-2442, 2017 | 57 | 2017 |
Kinetics and spontaneous open probability conferred by the ϵ subunit of the GABAA receptor DA Wagner, MP Goldschen-Ohm, TG Hales, MV Jones Journal of Neuroscience 25 (45), 10462-10468, 2005 | 56 | 2005 |
Evolutionarily conserved intracellular gate of voltage-dependent sodium channels K Oelstrom, MP Goldschen-Ohm, M Holmgren, B Chanda Nature Communications 5 (1), 3420, 2014 | 54 | 2014 |
An epilepsy-related region in the GABAA receptor mediates long-distance effects on GABA and benzodiazepine binding sites MP Goldschen-Ohm, DA Wagner, S Petrou, MV Jones Molecular pharmacology 77 (1), 35-45, 2010 | 54 | 2010 |
Structure and dynamics underlying elementary ligand binding events in human pacemaking channels MP Goldschen-Ohm, VA Klenchin, DS White, JB Cowgill, Q Cui, ... Elife 5, e20797, 2016 | 49 | 2016 |
A nonequilibrium binary elements-based kinetic model for benzodiazepine regulation of GABAA receptors MP Goldschen-Ohm, A Haroldson, MV Jones, RA Pearce Journal of General Physiology 144 (1), 27-39, 2014 | 37 | 2014 |
Three arginines in the GABAA receptor binding pocket have distinct roles in the formation and stability of agonist-versus antagonist-bound complexes MP Goldschen-Ohm, DA Wagner, MV Jones Molecular pharmacology 80 (4), 647-656, 2011 | 32 | 2011 |
Top-down machine learning approach for high-throughput single-molecule analysis DS White, MP Goldschen-Ohm, RH Goldsmith, B Chanda Elife 9, e53357, 2020 | 29 | 2020 |
The intrinsically liganded cyclic nucleotide–binding homology domain promotes KCNH channel activation Y Zhao, MP Goldschen-Ohm, JH Morais-Cabral, B Chanda, ... Journal of General Physiology 149 (2), 249-260, 2017 | 27 | 2017 |
Benzodiazepine Modulation of GABAA Receptors: A Mechanistic Perspective MP Goldschen-Ohm Biomolecules 12 (12), 1784, 2022 | 23 | 2022 |
Batrachotoxin acts as a stent to hold open homotetrameric prokaryotic voltage-gated sodium channels RK Finol-Urdaneta, JR McArthur, MP Goldschen-Ohm, R Gaudet, ... Journal of General Physiology 151 (2), 186-199, 2019 | 21 | 2019 |
SnapShot: channel gating mechanisms MP Goldschen-Ohm, B Chanda Cell 170 (3), 594-594. e1, 2017 | 18 | 2017 |
A critical residue in the α1M2–M3 linker regulating mammalian GABAA receptor pore gating by diazepam JW Nors, S Gupta, MP Goldschen-Ohm Elife 10, e64400, 2021 | 13 | 2021 |
Probing gating mechanisms of sodium channels using pore blockers MP Goldschen-Ohm, B Chanda Voltage Gated Sodium Channels, 183-201, 2014 | 8 | 2014 |
Single-molecule imaging with cell-derived nanovesicles reveals early binding dynamics at a cyclic nucleotide-gated ion channel VR Patel, AM Salinas, D Qi, S Gupta, DJ Sidote, MP Goldschen-Ohm Nature Communications 12 (1), 6459, 2021 | 6 | 2021 |
Zinc activation of OTOP proton channels identifies structural elements of the gating apparatus B Teng, JP Kaplan, Z Liang, KS Chyung, MP Goldschen-Ohm, ER Liman Elife 12, e85317, 2023 | 3 | 2023 |
Unsupervised selection of optimal single-molecule time series idealization criterion A Bandyopadhyay, MP Goldschen-Ohm Biophysical Journal 120 (20), 4472-4483, 2021 | 3 | 2021 |