Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37 CK Vaughan, M Mollapour, JR Smith, A Truman, B Hu, VM Good, ... Molecular cell 31 (6), 886-895, 2008 | 241 | 2008 |
Epigenetic modifications in double-strand break DNA damage signaling and repair D Rossetto, AW Truman, SJ Kron, J Côté Clinical Cancer Research 16 (18), 4543-4552, 2010 | 201 | 2010 |
A two-hybrid screen of the yeast proteome for Hsp90 interactors uncovers a novel Hsp90 chaperone requirement in the activity of a stress-activated mitogen-activated protein … SH Millson, AW Truman, V King, C Prodromou, LH Pearl, PW Piper Eukaryotic Cell 4 (5), 849-860, 2005 | 194 | 2005 |
Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity M Mollapour, S Tsutsumi, AW Truman, W Xu, CK Vaughan, K Beebe, ... Molecular cell 41 (6), 672-681, 2011 | 187 | 2011 |
Yeast Mpk1 mitogen-activated protein kinase activates transcription through Swi4/Swi6 by a noncatalytic mechanism that requires upstream signal KY Kim, AW Truman, DE Levin Molecular and cellular biology 28 (8), 2579-2589, 2008 | 149 | 2008 |
CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression AW Truman, K Kristjansdottir, D Wolfgeher, N Hasin, S Polier, H Zhang, ... Cell 151 (6), 1308-1318, 2012 | 145 | 2012 |
Post-translational modifications of Hsp70 family proteins: Expanding the chaperone code Nitika, CM Porter, AW Truman, MC Truttmann Journal of Biological Chemistry 295 (31), 10689-10708, 2020 | 110 | 2020 |
Expressed as the sole Hsp90 of yeast, the α and β isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90β … SH Millson, AW Truman, A Rácz, B Hu, B Panaretou, J Nuttall, ... The FEBS journal 274 (17), 4453-4463, 2007 | 110 | 2007 |
Expressed in the Yeast Saccharomyces cerevisiae, Human ERK5 Is a Client of the Hsp90 Chaperone That Complements Loss of the Slt2p (Mpk1p) Cell Integrity … AW Truman, SH Millson, JM Nuttall, V King, M Mollapour, C Prodromou, ... Eukaryotic cell 5 (11), 1914-1924, 2006 | 77 | 2006 |
Yeast Mpk1 cell wall integrity mitogen-activated protein kinase regulates nucleocytoplasmic shuttling of the Swi6 transcriptional regulator KY Kim, AW Truman, S Caesar, G Schlenstedt, DE Levin Molecular biology of the cell 21 (9), 1609-1619, 2010 | 70 | 2010 |
Mps1 mediated phosphorylation of Hsp90 confers renal cell carcinoma sensitivity and selectivity to Hsp90 inhibitors MR Woodford, AW Truman, DM Dunn, SM Jensen, R Cotran, R Bullard, ... Cell reports 14 (4), 872-884, 2016 | 65 | 2016 |
In the yeast heat shock response, Hsf1-directed induction of Hsp90 facilitates the activation of the Slt2 (Mpk1) mitogen-activated protein kinase required for cell integrity AW Truman, SH Millson, JM Nuttall, M Mollapour, C Prodromou, PW Piper Eukaryotic cell 6 (4), 744-752, 2007 | 65 | 2007 |
c-Abl mediated tyrosine phosphorylation of Aha1 activates its co-chaperone function in cancer cells DM Dunn, MR Woodford, AW Truman, SM Jensen, J Schulman, T Caza, ... Cell reports 12 (6), 1006-1018, 2015 | 63 | 2015 |
Mechanism of Mpk1 mitogen-activated protein kinase binding to the Swi4 transcription factor and its regulation by a novel caffeine-induced phosphorylation AW Truman, KY Kim, DE Levin Molecular and cellular biology 29 (24), 6449-6461, 2009 | 61 | 2009 |
Investigating the protein-protein interactions of the yeast Hsp90 chaperone system by two-hybrid analysis: potential uses and limitations of this approach SH Millson, AW Truman, F Wolfram, V King, B Panaretou, C Prodromou, ... Cell stress & chaperones 9 (4), 359, 2004 | 55 | 2004 |
Yeast is selectively hypersensitised to heat shock protein 90 (Hsp90)-targetting drugs with heterologous expression of the human Hsp90β, a property that can be exploited in … PW Piper, B Panaretou, SH Millson, A Trumana, M Mollapour, LH Pearl, ... Gene 302 (1-2), 165-170, 2003 | 55 | 2003 |
Quantitative proteomics of the yeast Hsp70/Hsp90 interactomes during DNA damage reveal chaperone-dependent regulation of ribonucleotide reductase AW Truman, K Kristjansdottir, D Wolfgeher, N Ricco, A Mayampurath, ... Journal of proteomics 112, 285-300, 2015 | 46 | 2015 |
Cracking the chaperone code: cellular roles for Hsp70 phosphorylation AW Truman Trends in biochemical sciences 42 (12), 932-935, 2017 | 42 | 2017 |
Phosphorylation and ubiquitination regulate protein phosphatase 5 activity and its prosurvival role in kidney cancer N Dushukyan, DM Dunn, RA Sager, MR Woodford, DR Loiselle, ... Cell reports 21 (7), 1883-1895, 2017 | 42 | 2017 |
Not quite the SSAme: unique roles for the yeast cytosolic Hsp70s SK Lotz, LE Knighton, fnm Nitika, GW Jones, AW Truman Current Genetics 65, 1127-1134, 2019 | 39 | 2019 |