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Andrew Truman
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Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37
CK Vaughan, M Mollapour, JR Smith, A Truman, B Hu, VM Good, ...
Molecular cell 31 (6), 886-895, 2008
2412008
Epigenetic modifications in double-strand break DNA damage signaling and repair
D Rossetto, AW Truman, SJ Kron, J Côté
Clinical Cancer Research 16 (18), 4543-4552, 2010
2012010
A two-hybrid screen of the yeast proteome for Hsp90 interactors uncovers a novel Hsp90 chaperone requirement in the activity of a stress-activated mitogen-activated protein …
SH Millson, AW Truman, V King, C Prodromou, LH Pearl, PW Piper
Eukaryotic Cell 4 (5), 849-860, 2005
1942005
Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity
M Mollapour, S Tsutsumi, AW Truman, W Xu, CK Vaughan, K Beebe, ...
Molecular cell 41 (6), 672-681, 2011
1872011
Yeast Mpk1 mitogen-activated protein kinase activates transcription through Swi4/Swi6 by a noncatalytic mechanism that requires upstream signal
KY Kim, AW Truman, DE Levin
Molecular and cellular biology 28 (8), 2579-2589, 2008
1492008
CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression
AW Truman, K Kristjansdottir, D Wolfgeher, N Hasin, S Polier, H Zhang, ...
Cell 151 (6), 1308-1318, 2012
1452012
Post-translational modifications of Hsp70 family proteins: Expanding the chaperone code
Nitika, CM Porter, AW Truman, MC Truttmann
Journal of Biological Chemistry 295 (31), 10689-10708, 2020
1102020
Expressed as the sole Hsp90 of yeast, the α and β isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90β …
SH Millson, AW Truman, A Rácz, B Hu, B Panaretou, J Nuttall, ...
The FEBS journal 274 (17), 4453-4463, 2007
1102007
Expressed in the Yeast Saccharomyces cerevisiae, Human ERK5 Is a Client of the Hsp90 Chaperone That Complements Loss of the Slt2p (Mpk1p) Cell Integrity …
AW Truman, SH Millson, JM Nuttall, V King, M Mollapour, C Prodromou, ...
Eukaryotic cell 5 (11), 1914-1924, 2006
772006
Yeast Mpk1 cell wall integrity mitogen-activated protein kinase regulates nucleocytoplasmic shuttling of the Swi6 transcriptional regulator
KY Kim, AW Truman, S Caesar, G Schlenstedt, DE Levin
Molecular biology of the cell 21 (9), 1609-1619, 2010
702010
Mps1 mediated phosphorylation of Hsp90 confers renal cell carcinoma sensitivity and selectivity to Hsp90 inhibitors
MR Woodford, AW Truman, DM Dunn, SM Jensen, R Cotran, R Bullard, ...
Cell reports 14 (4), 872-884, 2016
652016
In the yeast heat shock response, Hsf1-directed induction of Hsp90 facilitates the activation of the Slt2 (Mpk1) mitogen-activated protein kinase required for cell integrity
AW Truman, SH Millson, JM Nuttall, M Mollapour, C Prodromou, PW Piper
Eukaryotic cell 6 (4), 744-752, 2007
652007
c-Abl mediated tyrosine phosphorylation of Aha1 activates its co-chaperone function in cancer cells
DM Dunn, MR Woodford, AW Truman, SM Jensen, J Schulman, T Caza, ...
Cell reports 12 (6), 1006-1018, 2015
632015
Mechanism of Mpk1 mitogen-activated protein kinase binding to the Swi4 transcription factor and its regulation by a novel caffeine-induced phosphorylation
AW Truman, KY Kim, DE Levin
Molecular and cellular biology 29 (24), 6449-6461, 2009
612009
Investigating the protein-protein interactions of the yeast Hsp90 chaperone system by two-hybrid analysis: potential uses and limitations of this approach
SH Millson, AW Truman, F Wolfram, V King, B Panaretou, C Prodromou, ...
Cell stress & chaperones 9 (4), 359, 2004
552004
Yeast is selectively hypersensitised to heat shock protein 90 (Hsp90)-targetting drugs with heterologous expression of the human Hsp90β, a property that can be exploited in …
PW Piper, B Panaretou, SH Millson, A Trumana, M Mollapour, LH Pearl, ...
Gene 302 (1-2), 165-170, 2003
552003
Quantitative proteomics of the yeast Hsp70/Hsp90 interactomes during DNA damage reveal chaperone-dependent regulation of ribonucleotide reductase
AW Truman, K Kristjansdottir, D Wolfgeher, N Ricco, A Mayampurath, ...
Journal of proteomics 112, 285-300, 2015
462015
Cracking the chaperone code: cellular roles for Hsp70 phosphorylation
AW Truman
Trends in biochemical sciences 42 (12), 932-935, 2017
422017
Phosphorylation and ubiquitination regulate protein phosphatase 5 activity and its prosurvival role in kidney cancer
N Dushukyan, DM Dunn, RA Sager, MR Woodford, DR Loiselle, ...
Cell reports 21 (7), 1883-1895, 2017
422017
Not quite the SSAme: unique roles for the yeast cytosolic Hsp70s
SK Lotz, LE Knighton, fnm Nitika, GW Jones, AW Truman
Current Genetics 65, 1127-1134, 2019
392019
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