A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer A Asgharpour, SC Cazanave, T Pacana, M Seneshaw, R Vincent, ... Journal of hepatology 65 (3), 579-588, 2016 | 491 | 2016 |
The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids P Puri, K Daita, A Joyce, F Mirshahi, PK Santhekadur, S Cazanave, ... Hepatology 67 (2), 534-548, 2018 | 353 | 2018 |
Preclinical models of non-alcoholic fatty liver disease PK Santhekadur, DP Kumar, AJ Sanyal Journal of hepatology 68 (2), 230-237, 2018 | 334 | 2018 |
Activation of transmembrane bile acid receptor TGR5 stimulates insulin secretion in pancreatic β cells DP Kumar, S Rajagopal, S Mahavadi, F Mirshahi, JR Grider, KS Murthy, ... Biochemical and biophysical research communications 427 (3), 600-605, 2012 | 211 | 2012 |
Activation of transmembrane bile acid receptor TGR5 modulates pancreatic islet α cells to promote glucose homeostasis DP Kumar, A Asgharpour, F Mirshahi, SH Park, S Liu, Y Imai, JL Nadler, ... Journal of Biological Chemistry 291 (13), 6626-6640, 2016 | 132 | 2016 |
The circulating microbiome signature and inferred functional metagenomics in alcoholic hepatitis P Puri, S Liangpunsakul, JE Christensen, VH Shah, PS Kamath, GJ Gores, ... Hepatology 67 (4), 1284-1302, 2018 | 128 | 2018 |
Release of GLP-1 and PYY in response to the activation of G protein-coupled bile acid receptor TGR5 is mediated by Epac/PLC-ε pathway and modulated by endogenous H2S V Bala, S Rajagopal, DP Kumar, AD Nalli, S Mahavadi, AJ Sanyal, ... Frontiers in physiology 5, 420, 2014 | 114 | 2014 |
The PPAR α/γ agonist saroglitazar improves insulin resistance and steatohepatitis in a diet induced animal model of nonalcoholic fatty liver disease DP Kumar, R Caffrey, J Marioneaux, PK Santhekadur, M Bhat, C Alonso, ... Scientific reports 10 (1), 9330, 2020 | 107 | 2020 |
Unique peptide substrate binding properties of 110-kDa heat-shock protein (Hsp110) determine its distinct chaperone activity X Xu, EB Sarbeng, C Vorvis, DP Kumar, L Zhou, Q Liu Journal of Biological Chemistry 287 (8), 5661-5672, 2012 | 103 | 2012 |
Etiology of Hepatocellular Carcinoma: Special Focus on Fatty Liver Disease D Suresh, AN Srinivas, DP Kumar Frontiers in Oncology, 2020 | 99 | 2020 |
Activation of G protein-coupled bile acid receptor, TGR5, induces smooth muscle relaxation via both Epac-and PKA-mediated inhibition of RhoA/Rho kinase pathway S Rajagopal, DP Kumar, S Mahavadi, S Bhattacharya, R Zhou, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 304 (5 …, 2013 | 82 | 2013 |
The multifaceted role of natriuretic peptides in metabolic syndrome SAJ Santhekadur PK, Kumar DP, Seneshaw M, Faridoddin M Biomed Pharmacother. 92, 826-835, 2017 | 76 | 2017 |
The four hydrophobic residues on the Hsp70 inter-domain linker have two distinct roles DP Kumar, C Vorvis, EB Sarbeng, VCC Ledesma, JE Willis, Q Liu Journal of molecular biology 411 (5), 1099-1113, 2011 | 75 | 2011 |
The transcriptomic signature of disease development and progression of nonalcoholic fatty liver disease S Cazanave, A Podtelezhnikov, K Jensen, M Seneshaw, DP Kumar, ... Scientific reports 7 (1), 17193, 2017 | 60 | 2017 |
Extracellular vesicles as inflammatory drivers in NAFLD AN Srinivas, D Suresh, PK Santhekadur, D Suvarna, DP Kumar Frontiers in immunology 11, 627424, 2021 | 54 | 2021 |
A regulatory role of apoptosis antagonizing transcription factor in the pathogenesis of nonalcoholic fatty liver disease and hepatocellular carcinoma DP Kumar, PK Santhekadur, M Seneshaw, F Mirshahi, ... Hepatology 69 (4), 1520-1534, 2019 | 44 | 2019 |
Bile acids: emerging role in management of liver diseases A Asgharpour, D Kumar, A Sanyal Hepatology international 9, 527-533, 2015 | 43 | 2015 |
Regulation of Gβγ i-dependent PLC-β3 activity in smooth muscle: inhibitory phosphorylation of PLC-β3 by PKA and PKG and stimulatory phosphorylation of Gα i-GTPase-activating … AD Nalli, DP Kumar, O Al-Shboul, S Mahavadi, JF Kuemmerle, JR Grider, ... Cell biochemistry and biophysics 70, 867-880, 2014 | 38 | 2014 |
Identification of a metabolic, transcriptomic, and molecular signature of patatin‐like phospholipase domain containing 3–mediated acceleration of steatohepatitis BA Banini, DP Kumar, S Cazanave, M Seneshaw, F Mirshahi, ... Hepatology 73 (4), 1290-1306, 2021 | 31 | 2021 |
RISC assembly and post-transcriptional gene regulation in Hepatocellular Carcinoma PK Santhekadur, DP Kumar Genes & diseases 7 (2), 199-204, 2020 | 30 | 2020 |