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Shane Duggan
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Inflammation and esophageal carcinogenesis
MMM Abdel-Latif, S Duggan, JV Reynolds, D Kelleher
Current opinion in pharmacology 9 (4), 396-404, 2009
1302009
Tribbles 3: a novel regulator of TLR2-mediated signaling in response to Helicobacter pylori lipopolysaccharide
SM Smith, AP Moran, SP Duggan, SE Ahmed, AS Mohamed, HJ Windle, ...
The Journal of Immunology 186 (4), 2462-2471, 2011
1022011
Tribbles 3: a novel regulator of TLR2-mediated signaling in response to Helicobacter pylori lipopolysaccharide
SM Smith, AP Moran, SP Duggan, SE Ahmed, AS Mohamed, HJ Windle, ...
The Journal of Immunology 186 (4), 2462-2471, 2011
1022011
Tribbles 3: a novel regulator of TLR2-mediated signaling in response to Helicobacter pylori lipopolysaccharide
SM Smith, AP Moran, SP Duggan, SE Ahmed, AS Mohamed, HJ Windle, ...
The Journal of Immunology 186 (4), 2462-2471, 2011
1022011
Gene expression analysis of diagnostic biopsies predicts pathological response to neoadjuvant chemoradiotherapy of esophageal cancer
SG Maher, CM Gillham, SP Duggan, PC Smyth, N Miller, C Muldoon, ...
Annals of surgery 250 (5), 729-737, 2009
932009
Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells
E Looby, MMM Abdel-Latif, V Athié-Morales, S Duggan, A Long, ...
BMC cancer 9, 1-15, 2009
802009
Low pH induces co-ordinate regulation of gene expression in oesophageal cells
SP Duggan, WM Gallagher, EJP Fox, MM Abdel-Latif, JV Reynolds, ...
Carcinogenesis 27 (2), 319-327, 2006
702006
Obstacles for T-lymphocytes in the tumour microenvironment: Therapeutic challenges, advances and opportunities beyond immune checkpoint
NK Verma, BHS Wong, ZS Poh, A Udayakumar, R Verma, RKJ Goh, ...
EBioMedicine 83, 2022
432022
New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid
F Májer, R Sharma, C Mullins, L Keogh, S Phipps, S Duggan, D Kelleher, ...
Bioorganic & medicinal chemistry 22 (1), 256-268, 2014
382014
An integrative genomic approach in oesophageal cells identifies TRB3 as a bile acid responsive gene, downregulated in Barrett's oesophagus, which regulates NF-κB activation and …
SP Duggan, FM Behan, M Kirca, S Smith, JV Reynolds, A Long, ...
Carcinogenesis 31 (5), 936-945, 2010
382010
High sensitivity cytokine detection in acute coronary syndrome reveals up-regulation of interferon gamma and interleukin-10 post myocardial infarction
KD Patel, SP Duggan, CA Currid, WM Gallagher, R McManus, D Kelleher, ...
Clinical Immunology 133 (2), 251-256, 2009
222009
Tribbles 3: a novel regulator of TLR2-mediated signaling in response to
SM Smith, AP Moran, SP Duggan, SE Ahmed, AS Mohamed, HJ Windle, ...
Helicobacter pylori, 2462-2471, 0
21
siRNA library screening identifies a druggable immune-signature driving esophageal adenocarcinoma cell growth
SP Duggan, C Garry, FM Behan, S Phipps, H Kudo, M Kirca, A Zaheer, ...
Cellular and Molecular Gastroenterology and Hepatology 5 (4), 569-590, 2018
202018
The characterization of an intestine-like genomic signature maintained during Barrett’s-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival
SP Duggan, FM Behan, M Kirca, A Zaheer, SA McGarrigle, JV Reynolds, ...
Scientific Reports 6 (1), 32638, 2016
192016
Combination therapy using inhalable GapmeR and recombinant ACE2 for COVID-19
NK Verma, MHUT Fazil, SP Duggan, D Kelleher
Frontiers in Molecular Biosciences 7, 197, 2020
112020
High Content imaging of Barrett’s-associated high-grade dysplasia cells after siRNA library screening reveals acid-responsive regulators of cellular transitions
SM Phipps, CE Garry, S Kamal, JD Johnson, J Gilmer, A Long, D Kelleher, ...
Cellular and Molecular Gastroenterology and Hepatology 10 (3), 601-622, 2020
52020
The immune underpinnings of Barrett’s-associated adenocarcinogenesis: a retrial of nefarious immunologic co-conspirators
L Tambunting, D Kelleher, SP Duggan
Cellular and Molecular Gastroenterology and Hepatology 13 (5), 1297-1315, 2022
42022
Inherited syndromes predisposing to inflammation and GI Cancer
S Duggan, D Prichard, M Kirca, D Kelleher
Inflammation and Gastrointestinal Cancers, 35-50, 2011
42011
S1635 Loss of Bile Acid Responsive Gene Retinoic Acid Receptor-Related Orphan Receptor A (Rora) in Barrett's Metaplasia, Implications for Refluxed Induced Signaling in …
SP Duggan, M Kirca, FM Behan, DP Kelleher
Gastroenterology 5 (138), S-243, 2010
12010
S1638 A Novel Genomic Intestinal Filter Identifies NR5A2 and TEAD1 as Novel Intestinal Transcription Factors With the Potential to Interact With Gata6 in the Development of …
M Kirca, SP Duggan, A Zaheer, DP Kelleher
Gastroenterology 5 (138), S-243-S-244, 2010
12010
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