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Eric D Kelsic
Eric D Kelsic
Dyno Therapeutics
Verified email at dynotx.com - Homepage
Title
Cited by
Cited by
Year
Comparing community structure to characteristics in online collegiate social networks
V Red, ED Kelsic, PJ Mucha, MA Porter
SIAM review 53 (3), 526-543, 2011
6512011
Spatiotemporal microbial evolution on antibiotic landscapes
M Baym, TD Lieberman, ED Kelsic, R Chait, R Gross, I Yelin, R Kishony
Science 353 (6304), 1147-1151, 2016
5412016
High-order species interactions shape ecosystem diversity
E Bairey, ED Kelsic, R Kishony
Nature communications 7 (1), 12285, 2016
3592016
Counteraction of antibiotic production and degradation stabilizes microbial communities
ED Kelsic, J Zhao, K Vetsigian, R Kishony
Nature 521 (7553), 516-519, 2015
3082015
Comprehensive AAV capsid fitness landscape reveals a viral gene and enables machine-guided design
PJ Ogden, ED Kelsic, S Sinai, GM Church
Science 366 (6469), 1139-1143, 2019
2752019
Deep diversification of an AAV capsid protein by machine learning
DH Bryant, A Bashir, S Sinai, NK Jain, PJ Ogden, PF Riley, GM Church, ...
Nature Biotechnology 39 (6), 691-696, 2021
2092021
High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR–Cas9 in yeast
X Guo, A Chavez, A Tung, Y Chan, C Kaas, Y Yin, R Cecchi, SL Garnier, ...
Nature biotechnology 36 (6), 540-546, 2018
872018
Variational auto-encoding of protein sequences
S Sinai, E Kelsic, GM Church, MA Nowak
arXiv preprint arXiv:1712.03346, 2017
782017
RNA structural determinants of optimal codons revealed by MAGE-Seq
ED Kelsic, H Chung, N Cohen, J Park, HH Wang, R Kishony
Cell systems 3 (6), 563-571. e6, 2016
702016
AdaLead: A simple and robust adaptive greedy search algorithm for sequence design
S Sinai, R Wang, A Whatley, S Slocum, E Locane, ED Kelsic
arXiv preprint arXiv:2010.02141, 2020
532020
Escape mutations circumvent a tradeoff between resistance to a beta-lactam and resistance to a beta-lactamase inhibitor
D Russ, F Glaser, E Shaer Tamar, I Yelin, M Baym, ED Kelsic, ...
Nature Communications 11 (1), 2029, 2020
342020
A primer on model-guided exploration of fitness landscapes for biological sequence design
S Sinai, ED Kelsic
arXiv preprint arXiv:2010.10614, 2020
272020
Generative AAV capsid diversification by latent interpolation
S Sinai, N Jain, GM Church, ED Kelsic
bioRxiv, 2021.04. 16.440236, 2021
252021
Overcoming immunological challenges limiting capsid-mediated gene therapy with machine learning
AZ Wec, KS Lin, JC Kwasnieski, S Sinai, J Gerold, ED Kelsic
Frontiers in Immunology 12, 674021, 2021
142021
Challenges and opportunities of machine-guided capsid engineering for gene therapy
ED Kelsic, GM Church
Cell Gene Ther. Insights 5 (4), 523-536, 2019
112019
Understanding complex networks with community finding algorithms
ED Kelsic
SURF, 2005
112005
Community structure in online collegiate social networks, eprint
AL Traud, ED Kelsic, PJ Mucha, MA Porter
arXiv preprint arXiv:0809.0690, 2009
62009
Deep Search: Next-Gen Strategies for Accelerating AAV Capsid Engineering
E Kelsic, S Sinai, P Ogden, M Nowak, G Church
MOLECULAR THERAPY 26 (5), 168-168, 2018
22018
High-throughput creation and functional profiling of eukaryotic DNA sequence variant libraries using CRISPR/Cas9
X Guo, A Chavez, A Tung, Y Chan, R Cecchi, SL Garnier, C Kaas, ...
bioRxiv, 195776, 2017
22017
Efficient design of optimized AAV capsids using multi-property machine learning models trained across cells, organs and species
S Abestesh, I Akartuna, A Brown, M Cramer, F Damani, J Gerold, J Gorns, ...
MOLECULAR THERAPY 29 (4), 12-12, 2021
12021
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