Follow
Ronald Wetzel
Ronald Wetzel
Professor Emeritus, Structural Biology, U. Pittsburgh SOM
Verified email at pitt.edu - Homepage
Title
Cited by
Cited by
Year
Recombinant immunoglobin preparations
S Cabilly, HL Heyneker, WE Holmes, AD Riggs, RB Wetzel
US Patent 4,816,567, 1989
67401989
Huntington disease
GP Bates, R Dorsey, JF Gusella, MR Hayden, C Kay, BR Leavitt, M Nance, ...
Nature Reviews Disease Primers, 2015
14152015
Huntington Disease
GP BATES, R DORSEY, JF GUSELLA, MR HAYDEN, C KAY, ...
Nature Reviews Disease Primers, article number 15005. doi: 10.1038/ nrdp, 2015
14152015
Methods of producing immunoglobulins, vectors and transformed host cells for use therein
S Cabilly, HL Heyneker, WE Holmes, AD Riggs, RB Wetzel
US Patent 6,331,415, 2001
8102001
Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation
S Chen, FA Ferrone, R Wetzel
Proceedings of the National Academy of sciences 99 (18), 11884-11889, 2002
6542002
Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins
P Venkatraman, R Wetzel, M Tanaka, N Nukina, AL Goldberg
Molecular cell 14 (1), 95-104, 2004
5172004
Disulfide bond engineered into T4 lysozyme: stabilization of the protein toward thermal inactivation
LJ Perry, R Wetzel
Science 226 (4674), 555-557, 1984
4941984
Seeding specificity in amyloid growth induced by heterologous fibrils
B O'Nuallain, AD Williams, P Westermark, R Wetzel
Journal of Biological Chemistry 279 (17), 17490-17499, 2004
4822004
Mapping Aβ amyloid fibril secondary structure using scanning proline mutagenesis
AD Williams, E Portelius, I Kheterpal, J Guo, KD Cook, Y Xu, R Wetzel
Journal of molecular biology 335 (3), 833-842, 2004
4682004
Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism
AK Thakur, M Jayaraman, R Mishra, M Thakur, VM Chellgren, IJ L Byeon, ...
Nature structural & molecular biology 16 (4), 380-389, 2009
4612009
Physical, morphological and functional differences between pH 5.8 and 7.4 aggregates of the Alzheimer's amyloid peptide A β
SJ Wood, B Maleeff, T Hart, R Wetzel
Journal of molecular biology 256 (5), 870-877, 1996
4561996
Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells
W Yang, JR Dunlap, RB Andrews, R Wetzel
Human molecular genetics 11 (23), 2905-2917, 2002
4492002
Polymorphism in the intermediates and products of amyloid assembly
R Kodali, R Wetzel
Current opinion in structural biology 17 (1), 48-57, 2007
4452007
Conformational Abs recognizing a generic amyloid fibril epitope
B O'Nuallain, R Wetzel
Proceedings of the National Academy of Sciences 99 (3), 1485-1490, 2002
4412002
Prolines and Amyloidogenicity in Fragments of the Alzheimer's Peptide. beta./A4
SJ Wood, R Wetzel, JD Martin, MR Hurle
Biochemistry 34 (3), 724-730, 1995
4391995
A role for destabilizing amino acid replacements in light-chain amyloidosis.
MR Hurle, LR Helms, LIN Li, W Chan, R Wetzel
Proceedings of the National Academy of Sciences 91 (12), 5446-5450, 1994
4171994
Amyloid-like features of polyglutamine aggregates and their assembly kinetics
S Chen, V Berthelier, JB Hamilton, B O'Nuallai, R Wetzel
Biochemistry 41 (23), 7391-7399, 2002
4132002
Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity
S Chen, V Berthelier, W Yang, R Wetzel
Journal of molecular biology 311 (1), 173-182, 2001
3922001
Absence of behavioral abnormalities and neurodegeneration in vivo despite widespread neuronal huntingtin inclusions
EJ Slow, RK Graham, AP Osmand, RS Devon, G Lu, Y Deng, J Pearson, ...
Proceedings of the National Academy of Sciences 102 (32), 11402-11407, 2005
3732005
Amyloid adhesins are abundant in natural biofilms
P Larsen, JL Nielsen, MS Dueholm, R Wetzel, D Otzen, PH Nielsen
Environmental microbiology 9 (12), 3077-3090, 2007
3562007
The system can't perform the operation now. Try again later.
Articles 1–20