| Nomograms in oncology: more than meets the eye VP Balachandran, M Gonen, JJ Smith, RP DeMatteo The lancet oncology 16 (4), e173-e180, 2015 | 2381 | 2015 |
| PD-1 blockade in mismatch repair–deficient, locally advanced rectal cancer A Cercek, M Lumish, J Sinopoli, J Weiss, J Shia, M Lamendola-Essel, ... New England Journal of Medicine 386 (25), 2363-2376, 2022 | 754 | 2022 |
| Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer JJ Smith, NG Deane, F Wu, NB Merchant, B Zhang, A Jiang, P Lu, ... Gastroenterology 138 (3), 958-968, 2010 | 679 | 2010 |
| Adoption of total neoadjuvant therapy for locally advanced rectal cancer A Cercek, CSD Roxburgh, P Strombom, JJ Smith, LKF Temple, GM Nash, ... JAMA oncology 4 (6), e180071-e180071, 2018 | 492 | 2018 |
| Assessment of a watch-and-wait strategy for rectal cancer in patients with a complete response after neoadjuvant therapy JJ Smith, P Strombom, OS Chow, CS Roxburgh, P Lynn, A Eaton, ... JAMA oncology 5 (4), e185896-e185896, 2019 | 434 | 2019 |
| Organ preservation in patients with rectal adenocarcinoma treated with total neoadjuvant therapy J Garcia-Aguilar, S Patil, MJ Gollub, JK Kim, JB Yuval, HM Thompson, ... Journal of clinical oncology 40 (23), 2546, 2022 | 367 | 2022 |
| A rectal cancer organoid platform to study individual responses to chemoradiation K Ganesh, C Wu, KP O’Rourke, BC Szeglin, Y Zheng, CEG Sauvé, ... Nature medicine 25 (10), 1607-1614, 2019 | 363 | 2019 |
| Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer … JJ Smith, OS Chow, MJ Gollub, GM Nash, LK Temple, MR Weiser, ... BMC cancer 15, 1-13, 2015 | 324 | 2015 |
| Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance JM Balko, RS Cook, DB Vaught, MG Kuba, TW Miller, NE Bhola, ... Nature medicine 18 (7), 1052-1059, 2012 | 309 | 2012 |
| Pretreatment neutrophil-to-lymphocyte ratio and mutational burden as biomarkers of tumor response to immune checkpoint inhibitors C Valero, M Lee, D Hoen, K Weiss, DW Kelly, PS Adusumilli, PK Paik, ... Nature communications 12 (1), 729, 2021 | 239 | 2021 |
| Association of preoperative and postoperative serum carcinoembryonic antigen and colon cancer outcome T Konishi, Y Shimada, M Hsu, L Tufts, R Jimenez-Rodriguez, A Cercek, ... JAMA oncology 4 (3), 309-315, 2018 | 215 | 2018 |
| Advances and challenges in treatment of locally advanced rectal cancer JJ Smith, J Garcia-Aguilar Journal of clinical oncology 33 (16), 1797, 2015 | 197 | 2015 |
| Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of β-catenin TJ Freeman, JJ Smith, X Chen, MK Washington, JT Roland, AL Means, ... Gastroenterology 142 (3), 562-571. e2, 2012 | 193 | 2012 |
| Tumor suppressor function of the plasma glutathione peroxidase gpx3 in colitis-associated carcinoma CW Barrett, W Ning, X Chen, JJ Smith, MK Washington, KE Hill, ... Cancer research 73 (3), 1245-1255, 2013 | 188 | 2013 |
| Patterns and prognostic relevance of PD-1 and PD-L1 expression in colorectal carcinoma LH Lee, MS Cavalcanti, NH Segal, JF Hechtman, MR Weiser, JJ Smith, ... Modern Pathology 29 (11), 1433-1442, 2016 | 187 | 2016 |
| Claudin-1 up-regulates the repressor ZEB-1 to inhibit E-cadherin expression in colon cancer cells AB Singh, A Sharma, JJ Smith, M Krishnan, X Chen, S Eschrich, ... Gastroenterology 141 (6), 2140-2153, 2011 | 182 | 2011 |
| Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation P Dhawan, R Ahmad, R Chaturvedi, JJ Smith, R Midha, MK Mittal, ... Oncogene 30 (29), 3234-3247, 2011 | 172 | 2011 |
| Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas KT Nam, HJ Lee, JJ Smith, LA Lapierre, VP Kamath, X Chen, BJ Aronow, ... The Journal of clinical investigation 120 (3), 840-849, 2010 | 161 | 2010 |
| The association between tumor mutational burden and prognosis is dependent on treatment context C Valero, M Lee, D Hoen, J Wang, Z Nadeem, N Patel, MA Postow, ... Nature genetics 53 (1), 11-15, 2021 | 158 | 2021 |
| Mismatch repair–deficient rectal cancer and resistance to neoadjuvant chemotherapy A Cercek, G Dos Santos Fernandes, CS Roxburgh, K Ganesh, S Ng, ... Clinical Cancer Research 26 (13), 3271-3279, 2020 | 144 | 2020 |
Xi (Steven) ChenProfessor of Biostatistics, University of MiamiVerified email at miami.edu
