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Thilo Hagen
Thilo Hagen
Verified email at nus.edu.sg - Homepage
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Cited by
Year
Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, β cell dysfunction, and type 2 diabetes
CY Zhang, G Baffy, P Perret, S Krauss, O Peroni, D Grujic, T Hagen, ...
Cell 105 (6), 745-755, 2001
12062001
Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1α
T Hagen, CT Taylor, F Lam, S Moncada
Science 302 (5652), 1975-1978, 2003
8682003
Energy metabolism in uncoupling protein 3 gene knockout mice
AJ Vidal-Puig, D Grujic, CY Zhang, T Hagen, O Boss, Y Ido, A Szczepanik, ...
Journal of Biological Chemistry 275 (21), 16258-16266, 2000
8022000
Uncoupling proteins 2 and 3: potential regulators of mitochondrial energy metabolism.
O Boss, T Hagen, BB Lowell
Diabetes 49 (2), 143-156, 2000
5522000
Stabilization of hypoxia-inducible factor-1α protein in hypoxia occurs independently of mitochondrial reactive oxygen species production
YL Chua, E Dufour, EP Dassa, P Rustin, HT Jacobs, CT Taylor, T Hagen
Journal of Biological Chemistry 285 (41), 31277-31284, 2010
2052010
Utilizing hydrogen sulfide as a novel anti‐cancer agent by targeting cancer glycolysis and p H imbalance
ZW Lee, XY Teo, EYW Tay, CH Tan, T Hagen, PK Moore, LW Deng
British journal of pharmacology 171 (18), 4322-4336, 2014
1422014
Characterisation of the phosphorylation of β-catenin at the GSK-3 priming site Ser45
T Hagen, A Vidal-Puig
Biochemical and biophysical research communications 294 (2), 324-328, 2002
1382002
Inhibition of cellular respiration by endogenously produced carbon monoxide
G D'Amico, F Lam, T Hagen, S Moncada
Journal of cell science 119 (11), 2291-2298, 2006
1352006
Expression and characterization of GSK-3 mutants and their effect on β-catenin phosphorylation in intact cells
T Hagen, E Di Daniel, AA Culbert, AD Reith
Journal of Biological Chemistry 277 (26), 23330-23335, 2002
1342002
Assessment of uncoupling activity of uncoupling protein 3 using a yeast heterologous expression system
CY Zhang, T Hagen, VK Mootha, LJ Slieker, BB Lowell
FEBS letters 449 (2-3), 129-134, 1999
1191999
Oxygen versus reactive oxygen in the regulation of HIF-1: the balance tips
T Hagen
Biochemistry research international 2012, 2012
1152012
GSK-3 inhibition by adenoviral FRAT1 overexpression is neuroprotective and induces Tau dephosphorylation and β-catenin stabilisation without elevation of glycogen synthase activity
AA Culbert, MJ Brown, S Frame, T Hagen, DAE Cross, B Bax, AD Reith
Febs Letters 507 (3), 288-294, 2001
1142001
Hydrogen sulfide donors in research and drug development
ZJ Song, MY Ng, ZW Lee, W Dai, T Hagen, PK Moore, D Huang, LW Deng, ...
MedChemComm 5 (5), 557-570, 2014
1132014
Cloning and functional characterization of an uncoupling protein homolog in hummingbirds
CR VIANNA, T HAGEN, CYU ZHANG, E BACHMAN, O BOSS, ...
Physiological Genomics 5 (3), 137-145, 2001
1082001
Oncogenic activation of the PI3K/Akt pathway promotes cellular glucose uptake by downregulating the expression of thioredoxin-interacting protein
SY Hong, FX Yu, Y Luo, T Hagen
Cellular signalling 28 (5), 377-383, 2016
1012016
Substrate-mediated regulation of cullin neddylation
EH Chew, T Hagen
Journal of Biological Chemistry 282 (23), 17032-17040, 2007
992007
Thioredoxin-interacting protein (Txnip) gene expression: sensing oxidative phosphorylation status and glycolytic rate
FX Yu, TF Chai, H He, T Hagen, Y Luo
Journal of biological chemistry 285 (33), 25822-25830, 2010
942010
Characterization of cullin-based E3 ubiquitin ligases in intact mammalian cells—evidence for cullin dimerization
EH Chew, T Poobalasingam, CJ Hawkey, T Hagen
Cellular signalling 19 (5), 1071-1080, 2007
822007
Inhibition of mitochondrial respiration by the anticancer agent 2-methoxyestradiol
T Hagen, G D’Amico, M Quintero, M Palacios-Callender, V Hollis, F Lam, ...
Biochemical and biophysical research communications 322 (3), 923-929, 2004
812004
Inhibition of hypoxia-inducible factor-1α (HIF-1α) protein synthesis by DNA damage inducing agents
JJW Lou, YL Chua, EH Chew, J Gao, M Bushell, T Hagen
PloS one 5 (5), e10522, 2010
712010
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