| The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds YM Báez-Santos, SES John, AD Mesecar Antiviral research 115, 21-38, 2015 | 860 | 2015 |
| Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga, L Pache, ... Nature 586 (7827), 113-119, 2020 | 726 | 2020 |
| The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity N Barretto, D Jukneliene, K Ratia, Z Chen, AD Mesecar, SC Baker Journal of virology 79 (24), 15189-15198, 2005 | 595 | 2005 |
| Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2 AL Eggler, G Liu, JM Pezzuto, RB Van Breemen, AD Mesecar Proceedings of the National Academy of Sciences 102 (29), 10070-10075, 2005 | 520 | 2005 |
| The allosteric regulation of pyruvate kinase by fructose-1, 6-bisphosphate MS Jurica, A Mesecar, PJ Heath, W Shi, T Nowak, BL Stoddard Structure 6 (2), 195-210, 1998 | 506 | 1998 |
| A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication K Ratia, S Pegan, J Takayama, K Sleeman, M Coughlin, S Baliji, ... Proceedings of the National Academy of Sciences 105 (42), 16119-16124, 2008 | 486 | 2008 |
| Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis JD Dombrauckas, BD Santarsiero, AD Mesecar Foundations of Crystallography 61 (a1), 186-186, 2005 | 470 | 2005 |
| Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme K Ratia, KS Saikatendu, BD Santarsiero, N Barretto, SC Baker, ... Proceedings of the National Academy of Sciences 103 (15), 5717-5722, 2006 | 447 | 2006 |
| Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-κB signaling M Frieman, K Ratia, RE Johnston, AD Mesecar, RS Baric Journal of virology 83 (13), 6689-6705, 2009 | 404 | 2009 |
| Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms: direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding X Zhang, L Gan, H Pan, S Guo, X He, ST Olson, A Mesecar, S Adam, ... Journal of Biological Chemistry 277 (47), 45276-45284, 2002 | 374 | 2002 |
| Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases MA Clementz, Z Chen, BS Banach, Y Wang, L Sun, K Ratia, ... Journal of virology 84 (9), 4619-4629, 2010 | 348 | 2010 |
| Molecular mechanisms of natural products in chemoprevention: induction of cytoprotective enzymes by Nrf2 AL Eggler, KA Gay, AD Mesecar Molecular nutrition & food research 52 (S1), S84-S94, 2008 | 302 | 2008 |
| Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor JE Burdette, J Liu, S Chen, DS Fabricant, CE Piersen, EL Barker, ... Journal of Agricultural and Food Chemistry 51 (19), 5661-5670, 2003 | 298 | 2003 |
| Modification of keap1 cysteine residues by sulforaphane C Hu, AL Eggler, AD Mesecar, RB Van Breemen Chemical research in toxicology 24 (4), 515-521, 2011 | 293 | 2011 |
| Xanthohumol Isolated from Humulus lupulus Inhibits Menadione-Induced DNA Damage through Induction of Quinone Reductase BM Dietz, YH Kang, G Liu, AL Eggler, P Yao, LR Chadwick, GF Pauli, ... Chemical research in toxicology 18 (8), 1296-1305, 2005 | 285 | 2005 |
| Drug development and medicinal chemistry efforts toward SARS‐coronavirus and Covid‐19 therapeutics AK Ghosh, M Brindisi, D Shahabi, ME Chapman, AD Mesecar ChemMedChem 15 (11), 907-932, 2020 | 272 | 2020 |
| Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris BY Hwang, BN Su, H Chai, Q Mi, LBS Kardono, JJ Afriastini, S Riswan, ... The Journal of organic chemistry 69 (10), 3350-3358, 2004 | 266 | 2004 |
| Orbital steering in the catalytic power of enzymes: small structural changes with large catalytic consequences AD Mesecar, BL Stoddard, DE Koshland Jr Science 277 (5323), 202-206, 1997 | 266 | 1997 |
| MERS-CoV papain-like protease has deISGylating and deubiquitinating activities AM Mielech, A Kilianski, YM Baez-Santos, AD Mesecar, SC Baker Virology 450, 64-70, 2014 | 249 | 2014 |
| New Chemical Constituents of Euphorbia quinquecostata and Absolute Configuration Assignment by a Convenient Mosher Ester Procedure Carried Out in NMR … BN Su, EJ Park, ZH Mbwambo, BD Santarsiero, AD Mesecar, HHS Fong, ... Journal of Natural Products 65 (9), 1278-1282, 2002 | 226 | 2002 |
Bernard D SantarsieroResearch Professor, University of Illinois at ChicagoVerified email at uic.edu
