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Troy Messick
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MERIT40 controls BRCA1–Rap80 complex integrity and recruitment to DNA double-strand breaks
G Shao, J Patterson-Fortin, TE Messick, D Feng, N Shanbhag, Y Wang, ...
Genes & development 23 (6), 740-754, 2009
1762009
Biallelic Deleterious BRCA1 Mutations in a Woman with Early-Onset Ovarian Cancer
SM Domchek, J Tang, J Stopfer, DR Lilli, N Hamel, M Tischkowitz, ...
Cancer discovery 3 (4), 399-405, 2013
1742013
The ubiquitin landscape at DNA double-strand breaks
TE Messick, RA Greenberg
Journal of cell biology 187 (3), 319-326, 2009
1442009
Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein
TE Messick, NS Russell, AJ Iwata, KL Sarachan, R Shiekhattar, ...
Journal of Biological Chemistry 283 (16), 11038-11049, 2008
1352008
Differential regulation of JAMM domain deubiquitinating enzyme activity within the RAP80 complex
J Patterson-Fortin, G Shao, H Bretscher, TE Messick, RA Greenberg
Journal of biological chemistry 285 (40), 30971-30981, 2010
912010
Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex
JJ Ipsaro, SL Harper, TE Messick, R Marmorstein, A Mondragón, ...
Blood, The Journal of the American Society of Hematology 115 (23), 4843-4852, 2010
862010
Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth
TE Messick, GR Smith, SS Soldan, ME McDonnell, JS Deakyne, ...
Science translational medicine 11 (482), eaau5612, 2019
852019
Familial breast cancer screening reveals an alteration in the RAP80 UIM domain that impairs DNA damage response function
J Nikkilä, KA Coleman, D Morrissey, K Pylkäs, H Erkko, TE Messick, ...
Oncogene 28 (16), 1843-1852, 2009
802009
Development of a high-throughput screen for inhibitors of Epstein-Barr virus EBNA1
S Thompson, T Messick, DC Schultz, M Reichman, PM Lieberman
Journal of biomolecular screening 15 (9), 1107-1115, 2010
552010
Noncysteinyl Coordination to the [4Fe-4S]2+ Cluster of the DNA Repair Adenine Glycosylase MutY Introduced via Site-Directed Mutagenesis. Structural Characterization of an …
TE Messick, NH Chmiel, MP Golinelli, MR Langer, L Joshua-Tor, ...
Biochemistry 41 (12), 3931-3942, 2002
522002
Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr virus episomal latency
J Dheekollu, K Malecka, A Wiedmer, HJ Delecluse, AKS Chiang, ...
Oncotarget 8 (5), 7248, 2017
502017
Internal eliminated sequences interrupting the Oxytricha 81 locus: allelic divergence, conservation, conversions, and possible transposon origins.
A Seegmiller, KR Williams, RL Hammersmith, TG Doak, D Witherspoon, ...
Molecular biology and evolution 13 (10), 1351-1362, 1996
381996
Computational analysis of EBNA1 “druggability” suggests novel insights for Epstein-Barr virus inhibitor design
E Gianti, TE Messick, PM Lieberman, RJ Zauhar
Journal of computer-aided molecular design 30, 285-303, 2016
372016
Inhibition of pro-HGF activation by SRI31215, a novel approach to block oncogenic HGF/MET signaling
BY Owusu, N Bansal, PKM Venukadasula, LJ Ross, TE Messick, S Goel, ...
Oncotarget 7 (20), 29492, 2016
342016
The natural stilbenoid (–)-hopeaphenol inhibits cellular entry of SARS-CoV-2 USA-WA1/2020, B. 1.1. 7, and B. 1.351 variants
I Tietjen, J Cassel, ET Register, XY Zhou, TE Messick, F Keeney, LD Lu, ...
Antimicrobial Agents and Chemotherapy 65 (12), 10.1128/aac. 00772-21, 2021
262021
Epigenetic plasticity enables CNS-trafficking of EBV-infected B lymphocytes
SS Soldan, C Su, RJ Lamontagne, N Grams, F Lu, Y Zhang, JD Gesualdi, ...
PLoS Pathogens 17 (6), e1009618, 2021
262021
Design and synthesis of nonpeptide inhibitors of hepatocyte growth factor activation
PKM Venukadasula, BY Owusu, N Bansal, LJ Ross, JV Hobrath, D Bao, ...
ACS medicinal chemistry letters 7 (2), 177-181, 2016
252016
Cell-cycle-dependent EBNA1-DNA crosslinking promotes replication termination at oriP and viral episome maintenance
J Dheekollu, A Wiedmer, K Ayyanathan, JS Deakyne, TE Messick, ...
Cell 184 (3), 643-654. e13, 2021
242021
EBNA1 inhibitors have potent and selective antitumor activity in xenograft models of Epstein–Barr virus-associated gastric cancer
SS Soldan, EM Anderson, DM Frase, Y Zhang, LB Caruso, Y Wang, ...
Gastric Cancer 24 (5), 1076-1088, 2021
232021
Structural and functional basis for an EBNA1 hexameric ring in Epstein-Barr virus episome maintenance
JS Deakyne, KA Malecka, TE Messick, PM Lieberman
Journal of Virology 91 (19), 10.1128/jvi. 01046-17, 2017
232017
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