Hazem A. Ghabbour
Hazem A. Ghabbour
Assistant Professor Medicinal Chemistry Department, college of Pharmacy, Mansoura University.
Verified email at mans.edu.eg - Homepage
Title
Cited by
Cited by
Year
Sickle cell disease in S audi A rabia: the phenotype in adults with the A rab‐I ndian haplotype is not benign
A Alsultan, MK Alabdulaali, PJ Griffin, AM AlSuliman, HA Ghabbour, ...
British journal of haematology 164 (4), 597-604, 2014
632014
Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene) thiazolidin-2-ylidene) amino) benzenesulfonamides: synthesis, carbonic anhydrase inhibitory activity, anticancer activity and …
WM Eldehna, MF Abo-Ashour, A Nocentini, P Gratteri, IH Eissa, M Fares, ...
European Journal of Medicinal Chemistry 139, 250-262, 2017
542017
Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA …
WM Eldehna, H Almahli, GH Al-Ansary, HA Ghabbour, MH Aly, OE Ismael, ...
Journal of enzyme inhibition and medicinal chemistry 32 (1), 600-613, 2017
432017
Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII
WM Eldehna, M Fares, M Ceruso, HA Ghabbour, SM Abou-Seri, ...
European Journal of Medicinal Chemistry 110, 259-266, 2016
422016
Tandem Aldol-Michael reactions in aqueous diethylamine medium: A greener and efficient approach to bis-pyrimidine derivatives
AM Al-Majid, A Barakat, HJ AL-Najjar, YN Mabkhot, HA Ghabbour, ...
International journal of molecular sciences 14 (12), 23762-23773, 2013
412013
Novel indolin-2-one-based sulfonamides as carbonic anhydrase inhibitors: Synthesis, in vitro biological evaluation against carbonic anhydrases isoforms I, II, IV and VII and …
WM Eldehna, GH Al-Ansary, S Bua, A Nocentini, P Gratteri, A Altoukhy, ...
European journal of medicinal chemistry 127, 521-530, 2017
352017
Increasing the binding affinity of VEGFR-2 inhibitors by extending their hydrophobic interaction with the active site: Design, synthesis and biological evaluation of 1 …
WM Eldehna, SM Abou-Seri, AM El Kerdawy, RR Ayyad, AM Hamdy, ...
European Journal of Medicinal Chemistry 113, 50-62, 2016
352016
Synthesis, in vitro biological activities and in silico study of dihydropyrimidines derivatives
A Barakat, MS Islam, AM Al-Majid, HA Ghabbour, HK Fun, K Javed, ...
Bioorganic & Medicinal chemistry 23 (20), 6740-6748, 2015
352015
Sickle cell disease subphenotypes in patients from Southwestern Province of Saudi Arabia
A Alsultan, A Aleem, H Ghabbour, FH AlGahtani, A Al-Shehri, ME Osman, ...
Journal of Pediatric Hematology/Oncology 34 (2), 79, 2012
352012
Fluorescence spectroscopic and molecular docking studies of the binding interaction between the new anaplastic lymphoma kinase inhibitor crizotinib and bovine serum albumin
AS Abdelhameed, AM Alanazi, AH Bakheit, HW Darwish, HA Ghabbour, ...
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 171, 174-182, 2017
342017
Synthesis and structure investigation of novel pyrimidine-2, 4, 6-trione derivatives of highly potential biological activity as anti-diabetic agent
A Barakat, SM Soliman, AM Al-Majid, G Lotfy, HA Ghabbour, HK Fun, ...
Journal of Molecular Structure 1098, 365-376, 2015
322015
Novel [(3-indolylmethylene)hydrazono]indolin-2-ones as apoptotic anti-proliferative agents: design, synthesis and in vitro biological evaluation
WM Eldehna, MF Abo-Ashour, HS Ibrahim, GH Al-Ansary, HA Ghabbour, ...
Journal of enzyme inhibition and medicinal chemistry 33 (1), 686-700, 2018
302018
Synthesis of pyrimidine-2, 4, 6-trione derivatives: anti-oxidant, anti-cancer, α-glucosidase, β-glucuronidase inhibition and their molecular docking studies
A Barakat, MS Islam, AM Al-Majid, HA Ghabbour, S Yousuf, M Ashraf, ...
Bioorganic Chemistry 68, 72-79, 2016
282016
One-pot three-component synthesis of novel spirooxindoles with potential cytotoxic activity against triple-negative breast cancer MDA-MB-231 cells
WM Eldehna, DH El-Naggar, AR Hamed, HS Ibrahim, HA Ghabbour, ...
Journal of enzyme inhibition and medicinal chemistry 33 (1), 309-318, 2018
272018
Synthesis and cytotoxic activity of biphenylurea derivatives containing indolin-2-one moieties
WM Eldehna, M Fares, HS Ibrahim, MA Alsherbiny, MH Aly, HA Ghabbour, ...
Molecules 21 (6), 762, 2016
262016
Synthesis, crystal structure, and biological activity of cis/trans amide rotomers of (Z)-N′-(2-oxoindolin-3-ylidene) formohydrazide
HA Abdel-Aziz, HA Ghabbour, WM Eldehna, MM Qabeel, HK Fun
Journal of Chemistry 2014, 2014
262014
An efficient and green procedure for synthesis of rhodanine derivatives by aldol-thia-Michael protocol using aqueous diethylamine medium
A Barakat, AM Al-Majid, HJ Al-Najjar, YN Mabkhot, HA Ghabbour, HK Fun
RSC advances 4 (10), 4909-4916, 2014
262014
Synthesis and anticancer activity of new quinazoline derivatives
HA Abuelizz, M Marzouk, H Ghabbour, R Al-Salahi
Saudi Pharmaceutical Journal 25 (7), 1047-1054, 2017
252017
Ultrasonic promoted synthesis of novel s-triazine-Schiff base derivatives; molecular structure, spectroscopic studies and their preliminary anti-proliferative activities
A El-Faham, SM Soliman, HA Ghabbour, YA Elnakady, TA Mohaya, ...
Journal of Molecular Structure 1125, 121-135, 2016
252016
Development of novel synthesized phthalazinone-based PARP-1 inhibitors with apoptosis inducing mechanism in lung cancer
H Almahli, E Hadchity, MY Jaballah, R Daher, HA Ghabbour, MM Kabil, ...
Bioorganic chemistry 77, 443-456, 2018
242018
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Articles 1–20