| Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene) thiazolidin-2-ylidene) amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and … WM Eldehna, MF Abo-Ashour, A Nocentini, P Gratteri, IH Eissa, M Fares, ... European journal of medicinal chemistry 139, 250-262, 2017 | 121 | 2017 |
| Sickle cell disease in S audi A rabia: the phenotype in adults with the A rab‐I ndian haplotype is not benign A Alsultan, MK Alabdulaali, PJ Griffin, AM AlSuliman, HA Ghabbour, ... British journal of haematology 164 (4), 597-604, 2014 | 105 | 2014 |
| Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII WM Eldehna, M Fares, M Ceruso, HA Ghabbour, SM Abou-Seri, ... European journal of medicinal chemistry 110, 259-266, 2016 | 82 | 2016 |
| Increasing the binding affinity of VEGFR-2 inhibitors by extending their hydrophobic interaction with the active site: Design, synthesis and biological evaluation of 1 … WM Eldehna, SM Abou-Seri, AM El Kerdawy, RR Ayyad, AM Hamdy, ... European Journal of Medicinal Chemistry 113, 50-62, 2016 | 79 | 2016 |
| Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA … WM Eldehna, H Almahli, GH Al-Ansary, HA Ghabbour, MH Aly, OE Ismael, ... Journal of Enzyme Inhibition and Medicinal Chemistry 32 (1), 600-613, 2017 | 78 | 2017 |
| Fluorescence spectroscopic and molecular docking studies of the binding interaction between the new anaplastic lymphoma kinase inhibitor crizotinib and bovine serum albumin AS Abdelhameed, AM Alanazi, AH Bakheit, HW Darwish, HA Ghabbour, ... Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 171, 174-182, 2017 | 76 | 2017 |
| Synthesis and anticancer activity of new quinazoline derivatives HA Abuelizz, M Marzouk, H Ghabbour, R Al-Salahi Saudi Pharmaceutical Journal 25 (7), 1047-1054, 2017 | 69 | 2017 |
| Novel [(3-indolylmethylene)hydrazono]indolin-2-ones as apoptotic anti-proliferative agents: design, synthesis and in vitro biological evaluation WM Eldehna, MF Abo-Ashour, HS Ibrahim, GH Al-Ansary, HA Ghabbour, ... Journal of enzyme inhibition and medicinal chemistry 33 (1), 686-700, 2018 | 68 | 2018 |
| Development of novel synthesized phthalazinone-based PARP-1 inhibitors with apoptosis inducing mechanism in lung cancer H Almahli, E Hadchity, MY Jaballah, R Daher, HA Ghabbour, MM Kabil, ... Bioorganic Chemistry 77, 443-456, 2018 | 66 | 2018 |
| Synthesis and structure investigation of novel pyrimidine-2, 4, 6-trione derivatives of highly potential biological activity as anti-diabetic agent A Barakat, SM Soliman, AM Al-Majid, G Lotfy, HA Ghabbour, HK Fun, ... Journal of Molecular Structure 1098, 365-376, 2015 | 66 | 2015 |
| One-pot three-component synthesis of novel spirooxindoles with potential cytotoxic activity against triple-negative breast cancer MDA-MB-231 cells WM Eldehna, DH El-Naggar, AR Hamed, HS Ibrahim, HA Ghabbour, ... Journal of enzyme inhibition and medicinal chemistry 33 (1), 309-318, 2018 | 64 | 2018 |
| Novel indolin-2-one-based sulfonamides as carbonic anhydrase inhibitors: Synthesis, in vitro biological evaluation against carbonic anhydrases isoforms I, II, IV and VII and … WM Eldehna, GH Al-Ansary, S Bua, A Nocentini, P Gratteri, A Altoukhy, ... European Journal of Medicinal Chemistry 127, 521-530, 2017 | 64 | 2017 |
| Design and synthesis of new substituted spirooxindoles as potential inhibitors of the MDM2–p53 interaction A Barakat, MS Islam, HM Ghawas, AM Al-Majid, FF El-Senduny, ... Bioorganic Chemistry 86, 598-608, 2019 | 61 | 2019 |
| Substituted spirooxindole derivatives as potent anticancer agents through inhibition of phosphodiesterase 1 A Barakat, MS Islam, HM Ghawas, AM Al-Majid, FF El-Senduny, ... RSC advances 8 (26), 14335-14346, 2018 | 60 | 2018 |
| SLC-0111 enaminone analogs, 3/4-(3-aryl-3-oxopropenyl) aminobenzenesulfonamides, as novel selective subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform IX WM Eldehna, MF Abo-Ashour, E Berrino, D Vullo, HA Ghabbour, ... Bioorganic chemistry 83, 549-558, 2019 | 56 | 2019 |
| Synthesis, in vitro biological activities and in silico study of dihydropyrimidines derivatives A Barakat, MS Islam, AM Al-Majid, HA Ghabbour, HK Fun, K Javed, ... Bioorganic & medicinal chemistry 23 (20), 6740-6748, 2015 | 55 | 2015 |
| Sickle cell disease subphenotypes in patients from Southwestern Province of Saudi Arabia A Alsultan, A Aleem, H Ghabbour, FH AlGahtani, A Al-Shehri, ME Osman, ... Journal of Pediatric Hematology/Oncology 34 (2), 79, 2012 | 54 | 2012 |
| Synthesis, crystal structure, hirshfeld surface analysis, DFT calculations, anti-diabetic activity and molecular docking studies of (E)-N’-(5-bromo-2-hydroxybenzylidene … K Karrouchi, S Fettach, MM Jotani, A Sagaama, S Radi, HA Ghabbour, ... Journal of Molecular Structure 1221, 128800, 2020 | 53 | 2020 |
| Novel series of 6-(2-substitutedacetamido)-4-anilinoquinazolines as EGFR-ERK signal transduction inhibitors in MCF-7 breast cancer cells RSM Ismail, SM Abou-Seri, WM Eldehna, NSM Ismail, SM Elgazwi, ... European Journal of Medicinal Chemistry 155, 782-796, 2018 | 51 | 2018 |
| Tandem Aldol-Michael reactions in aqueous diethylamine medium: A greener and efficient approach to bis-pyrimidine derivatives AM Al-Majid, A Barakat, HJ Al-Najjar, YN Mabkhot, HA Ghabbour, HK Fun International Journal of Molecular Sciences 14 (12), 23762-23773, 2013 | 51 | 2013 |
Fun Hoong-KunProfessor, Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, RiyadhVerified email at usm.my
