| A high-throughput platform to identify small-molecule inhibitors of CRISPR-Cas9 B Maji, SA Gangopadhyay, M Lee, M Shi, P Wu, R Heler, B Mok, D Lim, ... Cell 177 (4), 1067-1079. e19, 2019 | 163 | 2019 |
| Orphan nuclear receptor estrogen-related receptor γ (ERRγ) is key regulator of hepatic gluconeogenesis DK Kim, D Ryu, M Koh, MW Lee, D Lim, MJ Kim, YH Kim, WJ Cho, ... Journal of Biological Chemistry 287 (26), 21628-21639, 2012 | 137 | 2012 |
| A small molecule binding HMGB1 and HMGB2 inhibits microglia-mediated neuroinflammation S Lee, Y Nam, JY Koo, D Lim, J Park, J Ock, J Kim, K Suk, SB Park Nature chemical biology 10 (12), 1055-1060, 2014 | 118 | 2014 |
| Precision control of CRISPR-Cas9 using small molecules and light SA Gangopadhyay, KJ Cox, D Manna, D Lim, B Maji, Q Zhou, ... Biochemistry 58 (4), 234-244, 2019 | 114 | 2019 |
| A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin … SS Choi, ES Kim, M Koh, SJ Lee, D Lim, YR Yang, HJ Jang, K Seo, ... Journal of Biological Chemistry 289 (38), 26618-26629, 2014 | 87 | 2014 |
| Discovery of a small-molecule inhibitor of protein–microRNA interaction using binding assay with a site-specifically labeled Lin28 D Lim, WG Byun, JY Koo, H Park, SB Park Journal of the American Chemical Society 138 (41), 13630-13638, 2016 | 66 | 2016 |
| CRISPR-based therapeutics: current challenges and future applications AE Modell, D Lim, TM Nguyen, V Sreekanth, A Choudhary Trends in pharmacological sciences 43 (2), 151-161, 2022 | 41 | 2022 |
| Treatment of sepsis pathogenesis with high mobility group box protein 1-regulating anti-inflammatory agents W Cho, JY Koo, Y Park, K Oh, S Lee, JS Song, MA Bae, D Lim, DS Lee, ... Journal of Medicinal Chemistry 60 (1), 170-179, 2017 | 40 | 2017 |
| Engineering designer beta cells with a CRISPR-Cas9 conjugation platform D Lim, V Sreekanth, KJ Cox, BK Law, BK Wagner, JM Karp, A Choudhary Nature communications 11 (1), 4043, 2020 | 39 | 2020 |
| Discovery of carbohybrid-based 2-aminopyrimidine analogues as a new class of rapid-acting antimalarial agents using image-based cytological profiling assay S Lee, D Lim, E Lee, N Lee, H Lee, J Cechetto, M Liuzzi, ... Journal of Medicinal Chemistry 57 (17), 7425-7434, 2014 | 35 | 2014 |
| Family-selective detection of antibiotics using antibody-functionalized carbon nanotube sensors B Kim, D Lim, HJ Jin, HY Lee, S Namgung, Y Ko, SB Park, S Hong Sensors and Actuators B: Chemical 166, 193-199, 2012 | 32 | 2012 |
| Discovery of small-molecule modulators of protein–RNA interactions by fluorescence intensity-based binding assay WG Byun, D Lim, SB Park ChemBioChem 21 (6), 818-824, 2020 | 29 | 2020 |
| Restoring let-7 microRNA biogenesis using a small-molecule inhibitor of the protein–RNA interaction D Lim, WG Byun, SB Park ACS Medicinal Chemistry Letters 9 (12), 1181-1185, 2018 | 29 | 2018 |
| Phenotypic Screening to Identify Small‐Molecule Enhancers for Glucose Uptake: Target Identification and Rational Optimization of Their Efficacy M Koh, J Park, JY Koo, D Lim, MY Cha, A Jo, JH Choi, SB Park Angewandte Chemie 126 (20), 5202-5206, 2014 | 28 | 2014 |
| Chemogenetic system demonstrates that Cas9 longevity impacts genome editing outcomes V Sreekanth, Q Zhou, P Kokkonda, HC Bermudez-Cabrera, D Lim, ... ACS Central Science 6 (12), 2228-2237, 2020 | 15 | 2020 |
| Synthesis of molecular frameworks containing two distinct heterocycles connected in a single molecule with enhanced three-dimensional shape diversity D Lim, SB Park Chem. Eur. J 19, 7100-7108, 2013 | 13 | 2013 |
| FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity N Wieder, JC Fried, C Kim, EH Sidhom, MR Brown, JL Marshall, ... Cell metabolism 35 (5), 887-905. e11, 2023 | 7 | 2023 |
| A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules D Lim, Q Zhou, KJ Cox, BK Law, M Lee, P Kokkonda, V Sreekanth, ... Nature cell biology 24 (12), 1766-1775, 2022 | 6 | 2022 |
| Electroenzymatic synthesis of (S)-styrene oxide employing zinc oxide/carbon black composite electrode D Lim, YH Kim, JC Joo, YJ Yoo Enzyme and microbial technology 47 (7), 313-321, 2010 | 6 | 2010 |
| Small molecules for enhancing the precision and safety of genome editing S Shin, S Jang, D Lim Molecules 27 (19), 6266, 2022 | 5 | 2022 |
