| Platelet signaling: a complex interplay between inhibitory and activatory networks AP Bye, AJ Unsworth, JM Gibbins Journal of Thrombosis and Haemostasis 14 (5), 918-930, 2016 | 188 | 2016 |
| Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib AP Bye, AJ Unsworth, MJ Desborough, CAT Hildyard, N Appleby, D Bruce, ... Blood advances 1 (26), 2610-2623, 2017 | 122 | 2017 |
| Ibrutinib Inhibits Platelet Integrin αIIbβ3 Outside-In Signaling and Thrombus Stability But Not Adhesion to Collagen AP Bye, AJ Unsworth, S Vaiyapuri, AR Stainer, MJ Fry, JM Gibbins Arteriosclerosis, thrombosis, and vascular biology 35 (11), 2326-2335, 2015 | 108 | 2015 |
| Pharmacological actions of nobiletin in the modulation of platelet function S Vaiyapuri, H Roweth, MS Ali, AJ Unsworth, AR Stainer, GD Flora, ... British journal of pharmacology 172 (16), 4133-4145, 2015 | 63 | 2015 |
| Non-genomic effects of nuclear receptors: insights from the anucleate platelet AJ Unsworth, GD Flora, JM Gibbins Cardiovascular research 114 (5), 645-655, 2018 | 53 | 2018 |
| The metabolites of the dietary flavonoid quercetin possess potent antithrombotic activity, and interact with aspirin to enhance antiplatelet effects AR Stainer, P Sasikumar, AP Bye, AJ Unsworth, LM Holbrook, M Tindall, ... Th Open 3 (03), e244-e258, 2019 | 52 | 2019 |
| Prevalence and prognostic significance of DNMT3A-and TET2-clonal haematopoiesis-driver mutations in patients presenting with ST-segment elevation myocardial infarction S Wang, S Hu, X Luo, X Bao, J Li, M Liu, Y Lv, C Zhao, M Zeng, X Chen, ... EBioMedicine 78, 2022 | 36 | 2022 |
| RXR ligands negatively regulate thrombosis and hemostasis AJ Unsworth, GD Flora, P Sasikumar, AP Bye, T Sage, N Kriek, ... Arteriosclerosis, thrombosis, and vascular biology 37 (5), 812-822, 2017 | 36 | 2017 |
| Optimizing platelet GPVI inhibition versus haemostatic impairment by the Btk inhibitors ibrutinib, acalabrutinib, ONO/GS-4059, BGB-3111 and evobrutinib V Denzinger, K Busygina, J Jamasbi, I Pekrul, M Spannagl, C Weber, ... Thrombosis and Haemostasis 119 (03), 397-406, 2019 | 35 | 2019 |
| Human platelet protein ubiquitylation and changes following GPVI activation AJ Unsworth, I Bombik, A Pinto-Fernandez, JF McGouran, R Konietzny, ... Thrombosis and haemostasis 119 (01), 104-116, 2019 | 34 | 2019 |
| Submaximal inhibition of protein kinase C restores ADP-induced dense granule secretion in platelets in the presence of Ca2+ AJ Unsworth, H Smith, P Gissen, SP Watson, CJ Pears Journal of Biological Chemistry 286 (24), 21073-21082, 2011 | 34 | 2011 |
| Farnesoid X receptor and its ligands inhibit the function of platelets LA Moraes, AJ Unsworth, S Vaiyapuri, MS Ali, P Sasikumar, T Sage, ... Arteriosclerosis, thrombosis, and vascular biology 36 (12), 2324-2333, 2016 | 32 | 2016 |
| PPARγ agonists negatively regulate αIIbβ3 integrin outside‐in signaling and platelet function through up‐regulation of protein kinase A activity AJ Unsworth, N Kriek, AP Bye, K Naran, T Sage, GD Flora, JM Gibbins Journal of Thrombosis and Haemostasis 15 (2), 356-369, 2017 | 31 | 2017 |
| EphB2 regulates contact-dependent and contact-independent signaling to control platelet function S Vaiyapuri, T Sage, RH Rana, MP Schenk, MS Ali, AJ Unsworth, ... Blood, The Journal of the American Society of Hematology 125 (4), 720-730, 2015 | 31 | 2015 |
| The direct thrombin inhibitors dabigatran and lepirudin inhibit GPIbα-mediated platelet aggregation K Trabold, S Makhoul, S Gambaryan, J van Ryn, U Walter, K Jurk Thrombosis and haemostasis 119 (06), 916-929, 2019 | 23 | 2019 |
| The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and hemostasis P Sasikumar, KS AlOuda, WJ Kaiser, LM Holbrook, N Kriek, AJ Unsworth, ... Journal of thrombosis and haemostasis 16 (5), 946-959, 2018 | 23 | 2018 |
| Overcoming ABCG2-mediated drug resistance with imidazo-[1, 2-b]-pyridazine-based Pim1 kinase inhibitors RAJ Darby, A Unsworth, S Knapp, ID Kerr, R Callaghan Cancer chemotherapy and pharmacology 76, 853-864, 2015 | 22 | 2015 |
| Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation JL Dunster, AJ Unsworth, AP Bye, EJ Haining, MA Sowa, Y Di, T Sage, ... Journal of Thrombosis and Haemostasis 18 (2), 485-496, 2020 | 19 | 2020 |
| Farnesoid X receptor and liver X receptor ligands initiate formation of coated platelets AJ Unsworth, AP Bye, DS Tannetta, MJR Desborough, N Kriek, T Sage, ... Arteriosclerosis, thrombosis, and vascular biology 37 (8), 1482-1493, 2017 | 19 | 2017 |
| Multiparameter phenotyping of platelet reactivity for stratification of human cohorts JL Dunster, AP Bye, N Kriek, T Sage, JL Mitchell, C Kempster, J Batista, ... Blood advances 5 (20), 4017-4030, 2021 | 18 | 2021 |
Jonathan GibbinsProfessor of Cell Biology, University of ReadingVerified email at reading.ac.uk
