| Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis JD Crane, R Palanivel, EP Mottillo, AL Bujak, H Wang, RJ Ford, A Collins, ... Nature medicine 21 (2), 166-172, 2015 | 485 | 2015 |
| AMP-activated protein kinase (AMPK) β1β2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise HM O'Neill, SJ Maarbjerg, JD Crane, J Jeppesen, SB Jørgensen, ... Proceedings of the National Academy of Sciences 108 (38), 16092-16097, 2011 | 476 | 2011 |
| Massage therapy attenuates inflammatory signaling after exercise-induced muscle damage JD Crane, DI Ogborn, C Cupido, S Melov, A Hubbard, JM Bourgeois, ... Science translational medicine 4 (119), 119ra13-119ra13, 2012 | 425 | 2012 |
| Lack of adipocyte AMPK exacerbates insulin resistance and hepatic steatosis through brown and beige adipose tissue function EP Mottillo, EM Desjardins, JD Crane, BK Smith, AE Green, S Ducommun, ... Cell metabolism 24 (1), 118-129, 2016 | 302 | 2016 |
| The effect of aging on human skeletal muscle mitochondrial and intramyocellular lipid ultrastructure JD Crane, MC Devries, A Safdar, MJ Hamadeh, MA Tarnopolsky Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2010 | 296 | 2010 |
| Emerging roles for serotonin in regulating metabolism: new implications for an ancient molecule JM Yabut, JD Crane, AE Green, DJ Keating, WI Khan, GR Steinberg Endocrine reviews 40 (4), 1092-1107, 2019 | 295 | 2019 |
| AMPK activation of muscle autophagy prevents fasting-induced hypoglycemia and myopathy during aging AL Bujak, JD Crane, JS Lally, RJ Ford, SJ Kang, IA Rebalka, AE Green, ... Cell metabolism 21 (6), 883-890, 2015 | 237 | 2015 |
| Exercise‐stimulated interleukin‐15 is controlled by AMPK and regulates skin metabolism and aging JD Crane, LG MacNeil, JS Lally, RJ Ford, AL Bujak, IK Brar, BE Kemp, ... Aging cell 14 (4), 625-634, 2015 | 183 | 2015 |
| Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity RJ Ford, MD Fullerton, SL Pinkosky, EA Day, JW Scott, JS Oakhill, ... Biochemical Journal 468 (1), 125-132, 2015 | 175 | 2015 |
| Fluvastatin causes NLRP3 inflammasome-mediated adipose insulin resistance BD Henriksbo, TC Lau, JF Cavallari, E Denou, W Chi, JS Lally, JD Crane, ... Diabetes 63 (11), 3742-3747, 2014 | 162 | 2014 |
| Protein synthesis and the expression of growth-related genes are altered by running in human vastus lateralis and soleus muscles MP Harber, JD Crane, JM Dickinson, B Jemiolo, U Raue, TA Trappe, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2009 | 128 | 2009 |
| Long-term aerobic exercise is associated with greater muscle strength throughout the life span JD Crane, LG MacNeil, MA Tarnopolsky Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2013 | 123 | 2013 |
| A standardized infrared imaging technique that specifically detects UCP1-mediated thermogenesis in vivo JD Crane, EP Mottillo, TH Farncombe, KM Morrison, GR Steinberg Molecular metabolism 3 (4), 490-494, 2014 | 111 | 2014 |
| Salsalate (salicylate) uncouples mitochondria, improves glucose homeostasis, and reduces liver lipids independent of AMPK-β1 BK Smith, RJ Ford, EM Desjardins, AE Green, MC Hughes, VP Houde, ... Diabetes 65 (11), 3352-3361, 2016 | 75 | 2016 |
| The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout DI Ogborn, BR McKay, JD Crane, G Parise, MA Tarnopolsky American Journal of Physiology-Regulatory, Integrative and Comparative …, 2014 | 71 | 2014 |
| Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice JE Kolesar, A Safdar, A Abadi, LG MacNeil, JD Crane, MA Tarnopolsky, ... Free Radical Biology and Medicine 75, 241-251, 2014 | 62 | 2014 |
| Effects of age and unaccustomed resistance exercise on mitochondrial transcript and protein abundance in skeletal muscle of men DI Ogborn, BR McKay, JD Crane, A Safdar, M Akhtar, G Parise, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2015 | 61 | 2015 |
| Supplementation with α-lipoic acid, CoQ10, and vitamin E augments running performance and mitochondrial function in female mice A Abadi, JD Crane, D Ogborn, B Hettinga, M Akhtar, A Stokl, L MacNeil, ... PloS one 8 (4), e60722, 2013 | 60 | 2013 |
| FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose … EP Mottillo, EM Desjardins, AM Fritzen, VZ Zou, JD Crane, JM Yabut, ... Molecular metabolism 6 (6), 471-481, 2017 | 57 | 2017 |
| Genetic deletion of mast cell serotonin synthesis prevents the development of obesity and insulin resistance JM Yabut, EM Desjardins, EJ Chan, EA Day, JM Leroux, B Wang, ... Nature communications 11 (1), 463, 2020 | 41 | 2020 |
Emilio MottilloHenry Ford Health SystemVerified email at hfhs.org
