The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU–rich element–dependent translation C Tiedje, N Ronkina, M Tehrani, S Dhamija, K Laass, H Holtmann, ... Public Library of Science 8 (9), e1002977, 2012 | 246 | 2012 |
The RNA-binding protein TTP is a global post-transcriptional regulator of feedback control in inflammation C Tiedje, MD Diaz-Munoz, P Trulley, H Ahlfors, K Laaß, PJ Blackshear, ... Nucleic acids research 44 (15), 7418-7440, 2016 | 144 | 2016 |
MAPKAP kinases MK2 and MK3 in inflammation: complex regulation of TNF biosynthesis via expression and phosphorylation of tristetraprolin N Ronkina, MB Menon, J Schwermann, C Tiedje, E Hitti, A Kotlyarov, ... Biochemical pharmacology 80 (12), 1915-1920, 2010 | 144 | 2010 |
The rho gdi rdi1 regulates rho gtpases by distinct mechanisms C Tiedje, I Sakwa, U Just, T Höfken Molecular biology of the cell 19 (7), 2885-2896, 2008 | 100 | 2008 |
ZAKα recognizes stalled ribosomes through partially redundant sensor domains AC Vind, G Snieckute, M Blasius, C Tiedje, N Krogh, DB Bekker-Jensen, ... Molecular cell 78 (4), 700-713. e7, 2020 | 95 | 2020 |
The role of mammalian MAPK signaling in regulation of cytokine mRNA stability and translation C Tiedje, H Holtmann, M Gaestel Journal of Interferon & Cytokine Research 34 (4), 220-232, 2014 | 85 | 2014 |
Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function VG D’Agostino, P Lal, B Mantelli, C Tiedje, C Zucal, N Thongon, ... Scientific reports 5 (1), 16478, 2015 | 83 | 2015 |
TRIF signaling stimulates translation of TNF-α mRNA via prolonged activation of MK2 P Gais, C Tiedje, F Altmayr, M Gaestel, H Weighardt, B Holzmann The Journal of Immunology 184 (10), 5842-5848, 2010 | 68 | 2010 |
Proteins involved in sterol synthesis interact with Ste20 and regulate cell polarity C Tiedje, DG Holland, U Just, T Hofken Journal of Cell Science 120 (20), 3613-3624, 2007 | 60 | 2007 |
GIGYF1/2-driven cooperation between ZNF598 and TTP in posttranscriptional regulation of inflammatory signaling MAX Tollenaere, C Tiedje, S Rasmussen, JC Nielsen, AC Vind, M Blasius, ... Cell Reports 26 (13), 3511-3521. e4, 2019 | 53 | 2019 |
p38MAPK/MK2-mediated phosphorylation of RBM7 regulates the human nuclear exosome targeting complex C Tiedje, M Lubas, M Tehrani, MB Menon, N Ronkina, S Rousseau, ... Rna 21 (2), 262-278, 2015 | 41 | 2015 |
LPS-induced production of TNF-α and IL-6 in mast cells is dependent on p38 but independent of TTP T Hochdörfer, C Tiedje, DJ Stumpo, PJ Blackshear, M Gaestel, M Huber Cellular signalling 25 (6), 1339-1347, 2013 | 39 | 2013 |
The role of TTP phosphorylation in the regulation of inflammatory cytokine production by MK2/3 N Ronkina, N Shushakova, C Tiedje, T Yakovleva, MAX Tollenaere, ... The Journal of Immunology 203 (8), 2291-2300, 2019 | 32 | 2019 |
A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells S Lee, D Micalizzi, SS Truesdell, SIA Bukhari, M Boukhali, ... Genome biology 21, 1-23, 2020 | 26 | 2020 |
Alternative translation initiation generates a functionally distinct isoform of the stress-activated protein kinase MK2 P Trulley, G Snieckute, D Bekker-Jensen, MB Menon, R Freund, ... Cell reports 27 (10), 2859-2870. e6, 2019 | 24 | 2019 |
Differentiated macrophages acquire a pro-inflammatory and cell death–resistant phenotype due to increasing XIAP and p38-mediated inhibition of RipK1 D Rijal, A Ariana, A Wight, K Kim, NA Alturki, Z Aamir, ES Ametepe, ... Journal of Biological Chemistry 293 (30), 11913-11927, 2018 | 24 | 2018 |
A translational silencing function of MCPIP1/Regnase-1 specified by the target site context G Behrens, R Winzen, N Rehage, A Dörrie, M Barsch, A Hoffmann, ... Nucleic Acids Research 46 (8), 4256-4270, 2018 | 24 | 2018 |
Endoplasmic reticulum-associated ubiquitin-conjugating enzyme Ube2j1 is a novel substrate of MK2 (MAPKAP kinase-2) involved in MK2-mediated TNFα production MB Menon, C Tiedje, J Lafera, N Ronkina, T Konen, A Kotlyarov, ... Biochemical Journal 456 (2), 163-172, 2013 | 24 | 2013 |
TIP 30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation A Grund, M Szaroszyk, M Korf‐Klingebiel, M Malek Mohammadi, ... EMBO molecular medicine 11 (10), e10018, 2019 | 21 | 2019 |
MAPKAP kinase 2 regulates IL-10 expression and prevents formation of intrahepatic myeloid cell aggregates during cytomegalovirus infections C Ehlting, M Trilling, C Tiedje, VTK Le-Trilling, U Albrecht, S Kluge, ... Journal of hepatology 64 (2), 380-389, 2016 | 21 | 2016 |