| The landscape of somatic copy-number alteration across human cancers R Beroukhim, CH Mermel, D Porter, G Wei, S Raychaudhuri, J Donovan, ... Nature 463 (7283), 899-905, 2010 | 3095 | 2010 |
| The immune landscape of cancer V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ... Immunity 48 (4), 812-830. e14, 2018 | 1067 | 2018 |
| High-throughput oncogene mutation profiling in human cancer RK Thomas, AC Baker, RM DeBiasi, W Winckler, T LaFramboise, WM Lin, ... Nature genetics 39 (3), 347-351, 2007 | 1066 | 2007 |
| Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion AH Zea, PC Rodriguez, MB Atkins, C Hernandez, S Signoretti, J Zabaleta, ... Cancer research 65 (8), 3044-3048, 2005 | 853 | 2005 |
| Comprehensive characterization of cancer driver genes and mutations MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ... Cell 173 (2), 371-385. e18, 2018 | 847 | 2018 |
| Essential roles of PI (3) K–p110β in cell growth, metabolism and tumorigenesis S Jia, Z Liu, S Zhang, P Liu, L Zhang, SH Lee, J Zhang, S Signoretti, ... Nature 454 (7205), 776-779, 2008 | 742 | 2008 |
| Oncogenic signaling pathways in the cancer genome atlas F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ... Cell 173 (2), 321-337. e10, 2018 | 721 | 2018 |
| p63 is a prostate basal cell marker and is required for prostate development S Signoretti, D Waltregny, J Dilks, B Isaac, D Lin, L Garraway, A Yang, ... The American journal of pathology 157 (6), 1769-1775, 2000 | 686 | 2000 |
| Renal cell carcinoma JJ Hsieh, MP Purdue, S Signoretti, C Swanton, L Albiges, M Schmidinger, ... Nature reviews Disease primers 3, 17009, 2017 | 675 | 2017 |
| Cell-of-origin patterns dominate the molecular classification of 10,000 tumors from 33 types of cancer KA Hoadley, C Yau, T Hinoue, DM Wolf, AJ Lazar, E Drill, R Shen, ... Cell 173 (2), 291-304. e6, 2018 | 655 | 2018 |
| Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN N Nakamura, S Ramaswamy, F Vazquez, S Signoretti, M Loda, ... Molecular and cellular biology 20 (23), 8969-8982, 2000 | 634 | 2000 |
| An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics J Liu, T Lichtenberg, KA Hoadley, LM Poisson, AJ Lazar, AD Cherniack, ... Cell 173 (2), 400-416. e11, 2018 | 633 | 2018 |
| Comprehensive analyses of tumor immunity: implications for cancer immunotherapy B Li, E Severson, JC Pignon, H Zhao, T Li, J Novak, P Jiang, H Shen, ... Genome biology 17 (1), 1-16, 2016 | 577 | 2016 |
| The somatic genomic landscape of chromophobe renal cell carcinoma CF Davis, CJ Ricketts, M Wang, L Yang, AD Cherniack, H Shen, C Buhay, ... Cancer cell 26 (3), 319-330, 2014 | 546 | 2014 |
| Genomic characterization of brain metastases reveals branched evolution and potential therapeutic targets PK Brastianos, SL Carter, S Santagata, DP Cahill, A Taylor-Weiner, ... Cancer discovery 5 (11), 1164-1177, 2015 | 526 | 2015 |
| Carbonic anhydrase IX expression predicts outcome of interleukin 2 therapy for renal cancer M Atkins, M Regan, D McDermott, J Mier, E Stanbridge, A Youmans, ... Clinical cancer research 11 (10), 3714-3721, 2005 | 500 | 2005 |
| Her-2-neu expression and progression toward androgen independence in human prostate cancer S Signoretti, R Montironi, J Manola, A Altimari, C Tam, G Bubley, S Balk, ... Journal of the National Cancer Institute 92 (23), 1918-1925, 2000 | 446 | 2000 |
| SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression Z Ding, CJ Wu, GC Chu, Y Xiao, D Ho, J Zhang, SR Perry, ES Labrot, ... Nature 470 (7333), 269-273, 2011 | 444 | 2011 |
| Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation N Bardeesy, M Sinha, AF Hezel, S Signoretti, NA Hathaway, ... Nature 419 (6903), 162-167, 2002 | 434 | 2002 |
| Loss or altered subcellular localization of p27 in Barrett's associated adenocarcinoma SP Singh, J Lipman, H Goldman, FH Ellis, L Aizenman, MG Cangi, ... Cancer research 58 (8), 1730-1735, 1998 | 412 | 1998 |
