| A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity S Khan, X Zhang, D Lv, Q Zhang, Y He, P Zhang, X Liu, D Thummuri, ... Nature medicine 25 (12), 1938-1947, 2019 | 398 | 2019 |
| Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity Y He, X Zhang, J Chang, HN Kim, P Zhang, Y Wang, S Khan, X Liu, ... Nature communications 11 (1), 1996, 2020 | 180 | 2020 |
| Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells S Shrivastava, P Kulkarni, D Thummuri, MK Jeengar, VGM Naidu, ... Apoptosis 19, 1148-1164, 2014 | 148 | 2014 |
| Thymoquinone prevents RANKL-induced osteoclastogenesis activation and osteolysis in an in vivo model of inflammation by suppressing NF-KB and MAPK Signalling D Thummuri, MK Jeengar, S Shrivastava, H Nemani, RN Ramavat, ... Pharmacological Research 99, 63-73, 2015 | 123 | 2015 |
| Design and synthesis of dithiocarbamate linked β-carboline derivatives: DNA topoisomerase II inhibition with DNA binding and apoptosis inducing ability A Kamal, M Sathish, VL Nayak, V Srinivasulu, B Kavitha, Y Tangella, ... Bioorganic & medicinal chemistry 23 (17), 5511-5526, 2015 | 90 | 2015 |
| Synthesis and biological evaluation of new benzimidazole-thiazolidinedione hybrids as potential cytotoxic and apoptosis inducing agents P Sharma, TS Reddy, D Thummuri, KR Senwar, NP Kumar, VGM Naidu, ... European journal of medicinal chemistry 124, 608-621, 2016 | 89 | 2016 |
| Long-term gemcitabine treatment reshapes the pancreatic tumor microenvironment and sensitizes murine carcinoma to combination immunotherapy DR Principe, M Narbutis, S Kumar, A Park, N Viswakarma, MJ Dorman, ... Cancer research 80 (15), 3101-3115, 2020 | 88 | 2020 |
| Cardamonin, a chalcone, inhibits human triple negative breast cancer cell invasiveness by downregulation of Wnt/β‐catenin signaling cascades and reversal of epithelial … S Shrivastava, MK Jeengar, D Thummuri, A Koval, VL Katanaev, ... Biofactors 43 (2), 152-169, 2017 | 86 | 2017 |
| Uridine ameliorates dextran sulfate sodium (DSS)-induced colitis in mice MK Jeengar, D Thummuri, M Magnusson, VGM Naidu, S Uppugunduri Scientific Reports 7 (1), 3924, 2017 | 83 | 2017 |
| Cellular senescence and radiation-induced pulmonary fibrosis Y He, D Thummuri, G Zheng, P Okunieff, DE Citrin, Z Vujaskovic, D Zhou Translational Research 209, 14-21, 2019 | 80 | 2019 |
| DT2216—a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas Y He, R Koch, V Budamagunta, P Zhang, X Zhang, S Khan, D Thummuri, ... Journal of hematology & oncology 13, 1-13, 2020 | 75 | 2020 |
| Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity D Lv, P Pal, X Liu, Y Jia, D Thummuri, P Zhang, W Hu, J Pei, Q Zhang, ... Nature communications 12 (1), 6896, 2021 | 73 | 2021 |
| Discovery of PROTAC BCL-XL degraders as potent anticancer agents with low on-target platelet toxicity X Zhang, D Thummuri, X Liu, W Hu, P Zhang, S Khan, Y Yuan, D Zhou, ... European journal of medicinal chemistry 192, 112186, 2020 | 72 | 2020 |
| New (E)-1-alkyl-1H-benzo [d] imidazol-2-yl) methylene) indolin-2-ones: Synthesis, in vitro cytotoxicity evaluation and apoptosis inducing studies P Sharma, D Thummuri, TS Reddy, KR Senwar, VGM Naidu, ... European journal of medicinal chemistry 122, 584-600, 2016 | 69 | 2016 |
| Design, synthesis and apoptosis inducing effect of novel (Z)-3-(3′-methoxy-4′-(2-amino-2-oxoethoxy)-benzylidene) indolin-2-ones as potential antitumour agents KR Senwar, TS Reddy, D Thummuri, P Sharma, VGM Naidu, ... European journal of medicinal chemistry 118, 34-46, 2016 | 67 | 2016 |
| Synthesis and biological evaluation of new rhodanine analogues bearing 2-chloroquinoline and benzo [h] quinoline scaffolds as anticancer agents V Ramesh, BA Rao, P Sharma, B Swarna, D Thummuri, K Srinivas, ... European Journal of Medicinal Chemistry 83, 569-580, 2014 | 65 | 2014 |
| Carnosic acid attenuates RANKL-induced oxidative stress and osteoclastogenesis via induction of Nrf2 and suppression of NF-κB and MAPK signalling D Thummuri, VGM Naidu, P Chaudhari Journal of Molecular Medicine 95, 1065-1076, 2017 | 64 | 2017 |
| Utilizing PROTAC technology to address the on-target platelet toxicity associated with inhibition of BCL-XL X Zhang, D Thummuri, Y He, X Liu, P Zhang, D Zhou, G Zheng Chemical Communications 55 (98), 14765-14768, 2019 | 62 | 2019 |
| Review on emu products for use as complementary and alternative medicine MK Jeengar, PS Kumar, D Thummuri, S Shrivastava, L Guntuku, R Sistla, ... Nutrition 31 (1), 21-27, 2015 | 50 | 2015 |
| IITZ-01, a novel potent lysosomotropic autophagy inhibitor, has single-agent antitumor efficacy in triple-negative breast cancer in vitro and in vivo L Guntuku, JK Gangasani, D Thummuri, RM Borkar, B Manavathi, ... Oncogene 38 (4), 581-595, 2019 | 43 | 2019 |
Sajid KhanAssistant Professor/Research at the University of Texas Health Science Center San AntonioVerified email at uthscsa.edu
