| METLIN: a technology platform for identifying knowns and unknowns C Guijas, JR Montenegro-Burke, X Domingo-Almenara, A Palermo, ... Analytical chemistry 90 (5), 3156-3164, 2018 | 857 | 2018 |
| Proteome-wide covalent ligand discovery in native biological systems KM Backus, BE Correia, KM Lum, S Forli, BD Horning, GE González-Páez, ... Nature 534 (7608), 570-574, 2016 | 720 | 2016 |
| Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic EN Chin, C Yu, VF Vartabedian, Y Jia, M Kumar, AM Gamo, W Vernier, ... Science 369 (6506), 993-999, 2020 | 289 | 2020 |
| Domain swapping in inducible nitric-oxide synthase: electron transfer occurs between flavin and heme groups located on adjacent subunits in the dimer U Siddhanta, A Presta, B Fan, D Wolan, DL Rousseau, DJ Stuehr Journal of biological chemistry 273 (30), 18950-18958, 1998 | 256 | 1998 |
| Small-molecule activators of a proenzyme DW Wolan, JA Zorn, DC Gray, JA Wells Science 326 (5954), 853-858, 2009 | 174 | 2009 |
| Acetone‐linked peptides: a convergent approach for peptide macrocyclization and labeling N Assem, DJ Ferreira, DW Wolan, PE Dawson Angewandte Chemie 127 (30), 8789-8792, 2015 | 167 | 2015 |
| Turning a protein kinase on or off from a single allosteric site via disulfide trapping JD Sadowsky, MA Burlingame, DW Wolan, CL McClendon, MP Jacobson, ... Proceedings of the National Academy of Sciences 108 (15), 6056-6061, 2011 | 161 | 2011 |
| SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase Q Zheng, JL Woehl, S Kitamura, D Santos-Martins, CJ Smedley, G Li, ... Proceedings of the National Academy of Sciences 116 (38), 18808-18814, 2019 | 143 | 2019 |
| Antifungal imidazoles block assembly of inducible NO synthase into an active dimer N Sennequier, D Wolan, DJ Stuehr Journal of Biological Chemistry 274 (2), 930-938, 1999 | 119 | 1999 |
| Sulfur (VI) fluoride exchange (SuFEx)-enabled high-throughput medicinal chemistry S Kitamura, Q Zheng, JL Woehl, A Solania, E Chen, N Dillon, MV Hull, ... Journal of the American Chemical Society 142 (25), 10899-10904, 2020 | 106 | 2020 |
| Crystal structure of the murine NK cell–activating receptor NKG2D at 1.95 Å DW Wolan, L Teyton, MG Rudolph, B Villmow, S Bauer, DH Busch, ... Nature immunology 2 (3), 248-254, 2001 | 101 | 2001 |
| Diversity oriented clicking (DOC): divergent synthesis of SuFExable pharmacophores from 2‐substituted‐alkynyl‐1‐sulfonyl fluoride (SASF) hubs CJ Smedley, G Li, AS Barrow, TL Gialelis, MC Giel, A Ottonello, Y Cheng, ... Angewandte Chemie 132 (30), 12560-12569, 2020 | 89 | 2020 |
| Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors C Li, L Xu, DW Wolan, IA Wilson, AJ Olson Journal of medicinal chemistry 47 (27), 6681-6690, 2004 | 89 | 2004 |
| Self-assembling small molecules form nanofibrils that bind procaspase-3 to promote activation JA Zorn, H Wille, DW Wolan, JA Wells Journal of the American Chemical Society 133 (49), 19630-19633, 2011 | 83 | 2011 |
| Inducible nitric oxide synthase: role of the N‐terminal β‐hairpin hook and pterin‐binding segment in dimerization and tetrahydrobiopterin interaction DK Ghosh, BR Crane, S Ghosh, D Wolan, R Gachhui, C Crooks, A Presta, ... The EMBO Journal, 1999 | 81 | 1999 |
| Mutational analysis of the tetrahydrobiopterin-binding site in inducible nitric-oxide synthase S Ghosh, D Wolan, S Adak, BR Crane, NS Kwon, JA Tainer, ED Getzoff, ... Journal of Biological Chemistry 274 (34), 24100-24112, 1999 | 77 | 1999 |
| Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria EN Bess, JE Bisanz, F Yarza, A Bustion, BE Rich, X Li, S Kitamura, ... Nature microbiology 5 (1), 56-66, 2020 | 74 | 2020 |
| Quantitative metaproteomics and activity-based probe enrichment reveals significant alterations in protein expression from a mouse model of inflammatory bowel disease MD Mayers, C Moon, GS Stupp, AI Su, DW Wolan Journal of proteome research 16 (2), 1014-1026, 2017 | 73 | 2017 |
| Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates CG Cheong, DW Wolan, SE Greasley, PA Horton, GP Beardsley, ... Journal of Biological Chemistry 279 (17), 18034-18045, 2004 | 71 | 2004 |
| Structure-based optimization and synthesis of antiviral drug Arbidol analogues with significantly improved affinity to influenza hemagglutinin ZVF Wright, NC Wu, RU Kadam, IA Wilson, DW Wolan Bioorganic & medicinal chemistry letters 27 (16), 3744-3748, 2017 | 63 | 2017 |
Seiya KitamuraThe Scripps Research InstituteVerified email at scripps.edu
