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Federico Mele
Federico Mele
Ricercatore
Verified email at irb.usi.ch
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Cited by
Year
Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology
L Piccoli, YJ Park, MA Tortorici, N Czudnochowski, AC Walls, ...
Cell 183 (4), 1024-1042. e21, 2020
12742020
Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β
CE Zielinski, F Mele, D Aschenbrenner, D Jarrossay, F Ronchi, ...
Nature 484 (7395), 514-518, 2012
10662012
Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection
K Stettler, M Beltramello, DA Espinosa, V Graham, A Cassotta, S Bianchi, ...
Science 353 (6301), 823-826, 2016
8382016
Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations
S Okada, JG Markle, EK Deenick, F Mele, D Averbuch, M Lagos, ...
Science 349 (6248), 606-613, 2015
4182015
Functional heterogeneity of human memory CD4+ T cell clones primed by pathogens or vaccines
S Becattini, D Latorre, F Mele, M Foglierini, C De Gregorio, A Cassotta, ...
Science 347 (6220), 400-406, 2015
3622015
T cells in patients with narcolepsy target self-antigens of hypocretin neurons
D Latorre, U Kallweit, E Armentani, M Foglierini, F Mele, A Cassotta, ...
Nature 562 (7725), 63-68, 2018
2752018
Memory T Cells in Latent Mycobacterium tuberculosis Infection Are Directed against Three Antigenic Islands and Largely Contained in a CXCR3+CCR6+ Th1 …
CS Lindestam Arlehamn, A Gerasimova, F Mele, R Henderson, J Swann, ...
PLoS pathogens 9 (1), e1003130, 2013
2462013
Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23
R Martínez-Barricarte, JG Markle, CS Ma, EK Deenick, N Ramírez-Alejo, ...
Science immunology 3 (30), eaau6759, 2018
1732018
Dissecting the human immunologic memory for pathogens
CE Zielinski, D Corti, F Mele, D Pinto, A Lanzavecchia, F Sallusto
Immunological reviews 240 (1), 40-51, 2011
1402011
Clonal analysis of immunodominance and cross-reactivity of the CD4 T cell response to SARS-CoV-2
JS Low, D Vaqueirinho, F Mele, M Foglierini, J Jerak, M Perotti, ...
Science 372 (6548), 1336-1341, 2021
1242021
Human T-bet governs innate and innate-like adaptive IFN-γ immunity against mycobacteria
R Yang, F Mele, L Worley, D Langlais, J Rosain, I Benhsaien, H Elarabi, ...
Cell 183 (7), 1826-1847. e31, 2020
1022020
Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency
XF Kong, R Martinez-Barricarte, J Kennedy, F Mele, T Lazarov, ...
Nature immunology 19 (9), 973-985, 2018
962018
ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies
JS Low, J Jerak, MA Tortorici, M McCallum, D Pinto, A Cassotta, ...
Science 377 (6607), 735-742, 2022
912022
Risk assessment and seroprevalence of SARS-CoV-2 infection in healthcare workers of COVID-19 and non-COVID-19 hospitals in Southern Switzerland
L Piccoli, P Ferrari, G Piumatti, S Jovic, BF Rodriguez, F Mele, ...
The Lancet Regional Health–Europe 1, 2021
832021
Immunological consequences of intragenus conservation of Mycobacterium tuberculosis T-cell epitopes
CS Lindestam Arlehamn, S Paul, F Mele, C Huang, JA Greenbaum, R Vita, ...
Proceedings of the National Academy of Sciences 112 (2), E147-E155, 2015
662015
ERK phosphorylation and miR-181a expression modulate activation of human memory TH17 cells
F Mele, C Basso, C Leoni, D Aschenbrenner, S Becattini, D Latorre, ...
Nature communications 6 (1), 6431, 2015
362015
Human IL-23 is essential for IFN-γ–dependent immunity to mycobacteria
Q Philippot, M Ogishi, J Bohlen, J Puchan, AA Arias, T Nguyen, ...
Science immunology 8 (80), eabq5204, 2023
302023
Phenotype and specificity of T cells in primary human cytomegalovirus infection during pregnancy: IL-7Rpos long-term memory phenotype is associated with …
F Mele, C Fornara, D Jarrossay, M Furione, A Arossa, A Spinillo, ...
PLoS One 12 (11), e0187731, 2017
242017
High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency
R Yang, M Weisshaar, F Mele, I Benhsaien, K Dorgham, J Han, CA Croft, ...
Journal of Experimental Medicine 218 (8), e20202726, 2021
232021
Follicular helper T-cells and virus-specific antibody response in primary and reactivated human cytomegalovirus infections of the immunocompetent and immunocompromised …
F Bruno, C Fornara, P Zelini, M Furione, E Carrara, L Scaramuzzi, I Cane, ...
Journal of General Virology 97 (8), 1928-1941, 2016
142016
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