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Martin Oft
Martin Oft
Synthekine
Verified email at synthekine.com
Title
Cited by
Cited by
Year
IL-23 promotes tumour incidence and growth
JL Langowski, X Zhang, L Wu, JD Mattson, T Chen, K Smith, B Basham, ...
Nature 442 (7101), 461-465, 2006
12392006
TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells.
M Oft, J Peli, C Rudaz, H Schwarz, H Beug, E Reichmann
Genes & development 10 (19), 2462-2477, 1996
8631996
TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis
M Oft, KH Heider, H Beug
Current Biology 8 (23), 1243-1252, 1998
8461998
Dinaciclib (SCH 727965), a novel and potent cyclin-dependent kinase inhibitor
D Parry, T Guzi, F Shanahan, N Davis, D Prabhavalkar, D Wiswell, ...
Molecular cancer therapeutics 9 (8), 2344-2353, 2010
5752010
IL-10 elicits IFNγ-dependent tumor immune surveillance
JB Mumm, J Emmerich, X Zhang, I Chan, L Wu, S Mauze, S Blaisdell, ...
Cancer cell 20 (6), 781-796, 2011
4652011
Metastasis is driven by sequential elevation of H-ras and Smad2 levels
M Oft, RJ Akhurst, A Balmain
Nature cell biology 4 (7), 487-494, 2002
4182002
IL-10: master switch from tumor-promoting inflammation to antitumor immunity
M Oft
Cancer immunology research 2 (3), 194-199, 2014
3002014
IL-10 Directly Activates and Expands Tumor-Resident CD8+ T Cells without De Novo Infiltration from Secondary Lymphoid Organs
J Emmerich, JB Mumm, IH Chan, D LaFace, H Truong, T McClanahan, ...
Cancer research 72 (14), 3570-3581, 2012
2952012
TGF-β inhibits p70 S6 kinase via protein phosphatase 2A to induce G1 arrest
C Petritsch, H Beug, A Balmain, M Oft
Genes & development 14 (24), 3093-3101, 2000
2912000
Inhibition of HIV-1 replication in lymphocytes by mutants of the Rev cofactor eIF-5A
D Bevec, H Jaksche, M Oft, T Wöhl, M Himmelspach, A Pacher, ...
Science 271 (5257), 1858-1860, 1996
2831996
Safety, antitumor activity, and immune activation of pegylated recombinant human interleukin-10 (AM0010) in patients with advanced solid tumors
A Naing, KP Papadopoulos, KA Autio, PA Ott, MR Patel, DJ Wong, ...
Journal of Clinical Oncology 34 (29), 3562, 2016
2322016
Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer
NR Blatner, MF Mulcahy, KL Dennis, D Scholtens, DJ Bentrem, ...
Science translational medicine 4 (164), 164ra159-164ra159, 2012
2232012
PEGylated IL-10 (Pegilodecakin) induces systemic immune activation, CD8+ T cell invigoration and polyclonal T cell expansion in cancer patients
A Naing, JR Infante, KP Papadopoulos, IH Chan, C Shen, NP Ratti, ...
Cancer Cell 34 (5), 775-791. e3, 2018
2192018
The estrogen-dependent c-JunER protein causes a reversible loss of mammary epithelial cell polarity involving a destabilization of adherens junctions.
I Fialka, H Schwarz, E Reichmann, M Oft, M Busslinger, H Beug
The Journal of cell biology 132 (6), 1115-1132, 1996
2061996
Swords into plowshares: IL-23 repurposes tumor immune surveillance
JL Langowski, RA Kastelein, M Oft
Trends in immunology 28 (5), 207-212, 2007
1802007
IL-23 suppresses innate immune response independently of IL-17A during carcinogenesis and metastasis
MWL Teng, DM Andrews, N McLaughlin, B Von Scheidt, SF Ngiow, ...
Proceedings of the National Academy of Sciences 107 (18), 8328-8333, 2010
1532010
Cytokine-based transformation of immune surveillance into tumor-promoting inflammation
JB Mumm, M Oft
Oncogene 27 (45), 5913-5919, 2008
1512008
Interaction of the HIV-1 rev cofactor eukaryotic initiation factor 5A with ribosomal protein L5
O Schatz, M Oft, C Dascher, M Schebesta, O Rosorius, H Jaksche, ...
Proceedings of the National Academy of Sciences 95 (4), 1607-1612, 1998
1161998
Pegilodecakin combined with pembrolizumab or nivolumab for patients with advanced solid tumours (IVY): a multicentre, multicohort, open-label, phase 1b trial
A Naing, DJ Wong, JR Infante, WM Korn, R Aljumaily, KP Papadopoulos, ...
The Lancet Oncology 20 (11), 1544-1555, 2019
942019
Functional analysis of the human immunodeficiency virus type 1 Rev protein oligomerization interface
SL Thomas, M Oft, H Jaksche, G Casari, P Heger, M Dobrovnik, D Bevec, ...
Journal of virology 72 (4), 2935-2944, 1998
901998
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