| Piperlongumine as a direct TrxR1 inhibitor with suppressive activity against gastric cancer P Zou, Y Xia, J Ji, W Chen, J Zhang, X Chen, V Rajamanickam, G Chen, ... Cancer letters 375 (1), 114-126, 2016 | 127 | 2016 |
| Chemopreventive effect of zingerone against colon carcinogenesis induced by 1, 2-dimethylhydrazine in rats R Vinothkumar, R Vinothkumar, M Sudha, N Nalini European journal of cancer prevention 23 (5), 361-371, 2014 | 92 | 2014 |
| Pharmacological aspects and potential use of phloretin: A systemic review AVA Mariadoss, R Vinyagam, V Rajamanickam, V Sankaran, ... Mini reviews in medicinal chemistry 19 (13), 1060-1067, 2019 | 89 | 2019 |
| Antiproliferative effect of p-Coumaric acid targets UPR activation by downregulating Grp78 in colon cancer SH Sharma, V Rajamanickam, S Nagarajan Chemico-Biological Interactions 291, 16-28, 2018 | 84 | 2018 |
| Role of hesperetin (a natural flavonoid) and its analogue on apoptosis in HT-29 human colon adenocarcinoma cell line–A comparative study G Sivagami, R Vinothkumar, CP Preethy, A Riyasdeen, MA Akbarsha, ... Food and chemical toxicology 50 (3-4), 660-671, 2012 | 84 | 2012 |
| Synergistic antitumor activity of rapamycin and EF24 via increasing ROS for the treatment of gastric cancer W Chen, P Zou, Z Zhao, X Chen, X Fan, R Vinothkumar, R Cui, F Wu, ... Redox biology 10, 78-89, 2016 | 78 | 2016 |
| Curcumin analog EF24 induces apoptosis via ROS-dependent mitochondrial dysfunction in human colorectal cancer cells G He, C Feng, R Vinothkumar, W Chen, X Dai, X Chen, Q Ye, C Qiu, ... Cancer chemotherapy and pharmacology 78, 1151-1161, 2016 | 75 | 2016 |
| Curcuminoid B63 induces ROS-mediated paraptosis-like cell death by targeting TrxR1 in gastric cells X Chen, X Chen, X Zhang, L Wang, P Cao, V Rajamanickam, C Wu, ... Redox biology 21, 101061, 2019 | 65 | 2019 |
| Pharmacological inhibition of MELK restricts ferroptosis and the inflammatory response in colitis and colitis-propelled carcinogenesis B Tang, J Zhu, S Fang, Y Wang, R Vinothkumar, M Li, Q Weng, Y Yang, ... Free Radical Biology and Medicine 172, 312-329, 2021 | 48 | 2021 |
| Curcuminoid EF24 enhances the anti‐tumour activity of Akt inhibitor MK‐2206 through ROS‐mediated endoplasmic reticulum stress and mitochondrial dysfunction in gastric cancer X Chen, X Dai, P Zou, W Chen, V Rajamanickam, C Feng, W Zhuge, ... British journal of pharmacology 174 (10), 1131-1146, 2017 | 47 | 2017 |
| Modulatory efficacy of rosmarinic acid on premalignant lesions and antioxidant status in 1, 2-dimethylhydrazine induced rat colon carcinogenesis V Karthikkumar, G Sivagami, R Vinothkumar, D Rajkumar, N Nalini Environmental Toxicology and Pharmacology 34 (3), 949-958, 2012 | 44 | 2012 |
| p-Coumaric acid attenuates alcohol exposed hepatic injury through MAPKs, apoptosis and Nrf2 signaling in experimental models R Sabitha, K Nishi, VP Gunasekaran, B Agilan, E David, G Annamalai, ... Chemico-biological interactions 321, 109044, 2020 | 43 | 2020 |
| Modulating effect of d‐carvone on 1,2‐dimethylhydrazine‐induced pre‐neoplastic lesions, oxidative stress and biotransforming enzymes, in an experimental model … R Vinothkumar, M Sudha, P Viswanathan, J Kabalimoorthy, ... Cell proliferation 46 (6), 705-720, 2013 | 43 | 2013 |
| Modulatory effect of troxerutin on biotransforming enzymes and preneoplasic lesions induced by 1, 2-dimethylhydrazine in rat colon carcinogenesis R Vinothkumar, RV Kumar, M Sudha, P Viswanathan, T Balasubramanian, ... Experimental and molecular pathology 96 (1), 15-26, 2014 | 41 | 2014 |
| Oral supplementation with troxerutin (trihydroxyethylrutin), modulates lipid peroxidation and antioxidant status in 1, 2-dimethylhydrazine-induced rat colon carcinogenesis R Vinothkumar, RV Kumar, V Karthikkumar, P Viswanathan, ... Environmental toxicology and pharmacology 37 (1), 174-184, 2014 | 39 | 2014 |
| Alantolactone promotes ER stress‐mediated apoptosis by inhibition of TrxR1 in triple‐negative breast cancer cell lines and in a mouse model C Yin, X Dai, X Huang, W Zhu, X Chen, Q Zhou, C Wang, C Zhao, P Zou, ... Journal of cellular and molecular medicine 23 (3), 2194-2206, 2019 | 33 | 2019 |
| (S)-crizotinib induces apoptosis in human non-small cell lung cancer cells by activating ROS independent of MTH1 X Dai, G Guo, P Zou, R Cui, W Chen, X Chen, C Yin, W He, ... Journal of Experimental & Clinical Cancer Research 36, 1-11, 2017 | 33 | 2017 |
| Increased Intracellular Reactive Oxygen Species Mediates the Anti‐Cancer Effects of WZ35 via Activating Mitochondrial Apoptosis Pathway in Prostate Cancer Cells M Chen, B Zhou, P Zhong, V Rajamanickam, X Dai, K Karvannan, H Zhou, ... The Prostate 77 (5), 489-504, 2017 | 32 | 2017 |
| Selective targeting of the TLR4 co-receptor, MD2, prevents colon cancer growth and lung metastasis V Rajamanickam, T Yan, S Xu, J Hui, X Xu, L Ren, Z Liu, G Liang, O Wang, ... International Journal of Biological Sciences 16 (8), 1288, 2020 | 31 | 2020 |
| Supplementation of p-coumaric acid exhibits chemopreventive effect via induction of Nrf2 in a short-term preclinical model of colon cancer SH Sharma, V Rajamanickam, S Nagarajan European Journal of Cancer Prevention 28 (6), 472-482, 2019 | 30 | 2019 |
