Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant S Perez-Miller, H Younus, R Vanam, CH Chen, D Mochly-Rosen, ... Nature structural & molecular biology 17 (2), 159-164, 2010 | 254 | 2010 |
Coenzyme Isomerization Is Integral to Catalysis in Aldehyde Dehydrogenase, SJ Perez-Miller, TD Hurley Biochemistry 42 (23), 7100-7109, 2003 | 200 | 2003 |
SARS-CoV-2 spike protein co-opts VEGF-A/neuropilin-1 receptor signaling to induce analgesia A Moutal, LF Martin, L Boinon, K Gomez, D Ran, Y Zhou, HJ Stratton, ... Pain 162 (1), 243-252, 2021 | 152 | 2021 |
Structural insights into TDP-43 and effects of post-translational modifications L François-Moutal, S Perez-Miller, DD Scott, VG Miranda, N Mollasalehi, ... Frontiers in molecular neuroscience 12, 301, 2019 | 104 | 2019 |
Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases M Khanna, CH Chen, A Kimble-Hill, B Parajuli, S Perez-Miller, ... Journal of Biological Chemistry 286 (50), 43486-43494, 2011 | 89 | 2011 |
Three‐dimensional structures of the three human class I alcohol dehydrogenases MS Niederhut, BJ Gibbons, S Perez‐Miller, TD Hurley Protein Science 10 (4), 697-706, 2001 | 77 | 2001 |
(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5 A Moutal, L François-Moutal, S Perez-Miller, K Cottier, LA Chew, SK Yeon, ... Molecular neurobiology 53, 1959-1976, 2016 | 60 | 2016 |
Inhibition of the Ubc9 E2 SUMO-conjugating enzyme–CRMP2 interaction decreases NaV1. 7 currents and reverses experimental neuropathic pain L François-Moutal, ET Dustrude, Y Wang, T Brustovetsky, A Dorame, W Ju, ... Pain 159 (10), 2115-2127, 2018 | 53 | 2018 |
Small Molecule Targeting TDP-43’s RNA Recognition Motifs Reduces Locomotor Defects in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS) L François-Moutal, R Felemban, DD Scott, MR Sayegh, VG Miranda, ... ACS chemical biology 14 (9), 2006-2013, 2019 | 48 | 2019 |
Homology‐guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2‐derived peptides A Moutal, W Li, Y Wang, W Ju, S Luo, S Cai, L François‐Moutal, ... British journal of pharmacology 175 (12), 2244-2260, 2018 | 41 | 2018 |
Targeting the CaVα–CaVβ interaction yields an antagonist of the N-type CaV2. 2 channel with broad antinociceptive efficacy R Khanna, J Yu, X Yang, A Moutal, A Chefdeville, V Gokhale, Z Shuja, ... Pain 160 (7), 1644-1661, 2019 | 37 | 2019 |
A single structurally conserved SUMOylation site in CRMP2 controls NaV1. 7 function ET Dustrude, S Perez-Miller, L François-Moutal, A Moutal, M Khanna, ... Channels 11 (4), 316-328, 2017 | 37 | 2017 |
Light chain C‐terminal region reinforces the stability of clathrin heavy chain trimers JA Ybe, S Perez‐Miller, Q Niu, DA Coates, MW Drazer, ME Clegg Traffic 8 (8), 1101-1110, 2007 | 37 | 2007 |
Novel compounds targeting neuropilin receptor 1 with potential to interfere with SARS-CoV-2 virus entry S Perez-Miller, M Patek, A Moutal, P Duran, CR Cabel, CA Thorne, ... ACS chemical neuroscience 12 (8), 1299-1312, 2021 | 36 | 2021 |
High resolution X‐ray structures of mouse major urinary protein nasal isoform in complex with pheromones S Perez‐Miller, Q Zou, MV Novotny, TD Hurley Protein Science 19 (8), 1469-1479, 2010 | 30 | 2010 |
Order and disorder in mitochondrial aldehyde dehydrogenase TD Hurley, S Perez-Miller, H Breen Chemico-Biological Interactions 130, 3-14, 2001 | 29 | 2001 |
The role of cyclin-dependent kinase 5 in neuropathic pain K Gomez, TGM Vallecillo, A Moutal, S Perez-Miller, R Delgado-Lezama, ... Pain 161 (12), 2674-2689, 2020 | 23 | 2020 |
The natural flavonoid naringenin elicits analgesia through inhibition of NaV1. 8 voltage-gated sodium channels Y Zhou, S Cai, A Moutal, J Yu, K Gómez, CL Madura, Z Shan, NYN Pham, ... ACS Chemical Neuroscience 10 (12), 4834-4846, 2019 | 23 | 2019 |
A novel variant in TAF1 affects gene expression and is associated with X-linked TAF1 intellectual disability syndrome SE Hurst, E Liktor-Busa, A Moutal, S Parker, S Rice, S Szelinger, ... Neuronal Signaling 2 (3), NS20180141, 2018 | 23 | 2018 |
Selective targeting of NaV1. 7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents S Cai, A Moutal, J Yu, LA Chew, J Isensee, R Chawla, K Gomez, S Luo, ... Science Translational Medicine 13 (619), eabh1314, 2021 | 22 | 2021 |