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Samantha Perez-Miller
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Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant
S Perez-Miller, H Younus, R Vanam, CH Chen, D Mochly-Rosen, ...
Nature structural & molecular biology 17 (2), 159-164, 2010
2542010
Coenzyme Isomerization Is Integral to Catalysis in Aldehyde Dehydrogenase,
SJ Perez-Miller, TD Hurley
Biochemistry 42 (23), 7100-7109, 2003
2002003
SARS-CoV-2 spike protein co-opts VEGF-A/neuropilin-1 receptor signaling to induce analgesia
A Moutal, LF Martin, L Boinon, K Gomez, D Ran, Y Zhou, HJ Stratton, ...
Pain 162 (1), 243-252, 2021
1522021
Structural insights into TDP-43 and effects of post-translational modifications
L François-Moutal, S Perez-Miller, DD Scott, VG Miranda, N Mollasalehi, ...
Frontiers in molecular neuroscience 12, 301, 2019
1042019
Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases
M Khanna, CH Chen, A Kimble-Hill, B Parajuli, S Perez-Miller, ...
Journal of Biological Chemistry 286 (50), 43486-43494, 2011
892011
Three‐dimensional structures of the three human class I alcohol dehydrogenases
MS Niederhut, BJ Gibbons, S Perez‐Miller, TD Hurley
Protein Science 10 (4), 697-706, 2001
772001
(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5
A Moutal, L François-Moutal, S Perez-Miller, K Cottier, LA Chew, SK Yeon, ...
Molecular neurobiology 53, 1959-1976, 2016
602016
Inhibition of the Ubc9 E2 SUMO-conjugating enzyme–CRMP2 interaction decreases NaV1. 7 currents and reverses experimental neuropathic pain
L François-Moutal, ET Dustrude, Y Wang, T Brustovetsky, A Dorame, W Ju, ...
Pain 159 (10), 2115-2127, 2018
532018
Small Molecule Targeting TDP-43’s RNA Recognition Motifs Reduces Locomotor Defects in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS)
L François-Moutal, R Felemban, DD Scott, MR Sayegh, VG Miranda, ...
ACS chemical biology 14 (9), 2006-2013, 2019
482019
Homology‐guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2‐derived peptides
A Moutal, W Li, Y Wang, W Ju, S Luo, S Cai, L François‐Moutal, ...
British journal of pharmacology 175 (12), 2244-2260, 2018
412018
Targeting the CaVα–CaVβ interaction yields an antagonist of the N-type CaV2. 2 channel with broad antinociceptive efficacy
R Khanna, J Yu, X Yang, A Moutal, A Chefdeville, V Gokhale, Z Shuja, ...
Pain 160 (7), 1644-1661, 2019
372019
A single structurally conserved SUMOylation site in CRMP2 controls NaV1. 7 function
ET Dustrude, S Perez-Miller, L François-Moutal, A Moutal, M Khanna, ...
Channels 11 (4), 316-328, 2017
372017
Light chain C‐terminal region reinforces the stability of clathrin heavy chain trimers
JA Ybe, S Perez‐Miller, Q Niu, DA Coates, MW Drazer, ME Clegg
Traffic 8 (8), 1101-1110, 2007
372007
Novel compounds targeting neuropilin receptor 1 with potential to interfere with SARS-CoV-2 virus entry
S Perez-Miller, M Patek, A Moutal, P Duran, CR Cabel, CA Thorne, ...
ACS chemical neuroscience 12 (8), 1299-1312, 2021
362021
High resolution X‐ray structures of mouse major urinary protein nasal isoform in complex with pheromones
S Perez‐Miller, Q Zou, MV Novotny, TD Hurley
Protein Science 19 (8), 1469-1479, 2010
302010
Order and disorder in mitochondrial aldehyde dehydrogenase
TD Hurley, S Perez-Miller, H Breen
Chemico-Biological Interactions 130, 3-14, 2001
292001
The role of cyclin-dependent kinase 5 in neuropathic pain
K Gomez, TGM Vallecillo, A Moutal, S Perez-Miller, R Delgado-Lezama, ...
Pain 161 (12), 2674-2689, 2020
232020
The natural flavonoid naringenin elicits analgesia through inhibition of NaV1. 8 voltage-gated sodium channels
Y Zhou, S Cai, A Moutal, J Yu, K Gómez, CL Madura, Z Shan, NYN Pham, ...
ACS Chemical Neuroscience 10 (12), 4834-4846, 2019
232019
A novel variant in TAF1 affects gene expression and is associated with X-linked TAF1 intellectual disability syndrome
SE Hurst, E Liktor-Busa, A Moutal, S Parker, S Rice, S Szelinger, ...
Neuronal Signaling 2 (3), NS20180141, 2018
232018
Selective targeting of NaV1. 7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents
S Cai, A Moutal, J Yu, LA Chew, J Isensee, R Chawla, K Gomez, S Luo, ...
Science Translational Medicine 13 (619), eabh1314, 2021
222021
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