Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders? F Nicoletti, V Bruno, A Copani, G Casabona, T Knöpfel Trends in neurosciences 19 (7), 267-271, 1996 | 543 | 1996 |
β-amyloid monomers are neuroprotective ML Giuffrida, F Caraci, B Pignataro, S Cataldo, P De Bona, V Bruno, ... Journal of Neuroscience 29 (34), 10582-10587, 2009 | 536 | 2009 |
Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs V Bruno, G Battaglia, A Copani, M D'Onofrio, P Di Iorio, A De Blasi, ... Journal of Cerebral Blood Flow & Metabolism 21 (9), 1013-1033, 2001 | 407 | 2001 |
Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-β V Bruno, G Battaglia, G Casabona, A Copani, F Caciagli, F Nicoletti Journal of Neuroscience 18 (23), 9594-9600, 1998 | 328 | 1998 |
Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path? A Copani, MA Sortino, F Nicoletti, V Bruno, D Ubertia, M Memo Trends in neurosciences 24 (1), 25-31, 2001 | 294 | 2001 |
Glia modulate the response of murine cortical neurons to excitotoxicity: glia exacerbate AMPA neurotoxicity LL Dugan, VM Bruno, SM Amagasu, RG Giffard Journal of Neuroscience 15 (6), 4545-4555, 1995 | 274 | 1995 |
Activation of A1 adenosine or mGlu3 metabotropic glutamate receptors enhances the release of nerve growth factor and S‐100β protein from cultured astrocytes R Ciccarelli, P Di Iorio, V Bruno, G Battaglia, I D'Alimonte, M D'onofrio, ... Glia 27 (3), 275-281, 1999 | 262 | 1999 |
(−)-PHCCC, a positive allosteric modulator of mGluR4: characterization, mechanism of action, and neuroprotection M Maj, V Bruno, Z Dragic, R Yamamoto, G Battaglia, W Inderbitzin, ... Neuropharmacology 45 (7), 895-906, 2003 | 239 | 2003 |
The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/neuroprotection C Corti, G Battaglia, G Molinaro, B Riozzi, A Pittaluga, M Corsi, ... Journal of Neuroscience 27 (31), 8297-8308, 2007 | 226 | 2007 |
TGF‐β1 Pathway as a New Target for Neuroprotection in Alzheimer's Disease F Caraci, G Battaglia, V Bruno, P Bosco, V Carbonaro, ML Giuffrida, ... CNS neuroscience & therapeutics 17 (4), 237-249, 2011 | 219 | 2011 |
Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide. A Copani, V Bruno, G Battaglia, G Leanza, R Pellitteri, A Russo, ... Molecular pharmacology 47 (5), 890-897, 1995 | 217 | 1995 |
Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells V Bruno, A Copani, T Knöpfel, R Kuhn, G Casabona, P Dell'Albani, ... Neuropharmacology 34 (8), 1089-1098, 1995 | 208 | 1995 |
Group-I metabotropic glutamate receptors: hypotheses to explain their dual role in neurotoxicity and neuroprotection F Nicoletti, V Bruno, MV Catania, G Battaglia, A Copani, G Barbagallo, ... Neuropharmacology 38 (10), 1477-1484, 1999 | 204 | 1999 |
(R, S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo F Gasparini, V Bruno, G Battaglia, S Lukic, T Leonhardt, W Inderbitzin, ... Journal of Pharmacology and Experimental Therapeutics 289 (3), 1678-1687, 1999 | 194 | 1999 |
Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration V Bruno, G Battaglia, A Copani, RG Giffard, G Raciti, R Raffaele, ... European Journal of Neuroscience 7 (9), 1906-1913, 1995 | 187 | 1995 |
The neuroprotective activity of group-II metabotropic glutamate receptors requires new protein synthesis and involves a glial–neuronal signaling V Bruno, FX Sureda, M Storto, G Casabona, A Caruso, T Knopfel, R Kuhn, ... Journal of Neuroscience 17 (6), 1891-1897, 1997 | 179 | 1997 |
Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is required for the development of ischemic neuronal death I Cappuccio, A Calderone, CL Busceti, F Biagioni, F Pontarelli, V Bruno, ... Journal of Neuroscience 25 (10), 2647-2657, 2005 | 175 | 2005 |
Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation F Fallarino, C Volpi, F Fazio, S Notartomaso, C Vacca, C Busceti, ... Nature medicine 16 (8), 897-902, 2010 | 173 | 2010 |
Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death V Bruno, A Copani, G Battaglia, R Raffaele, H Shinozaki, F Nicoletti European journal of pharmacology 256 (1), 109-112, 1994 | 164 | 1994 |
Selective blockade of metabotropic glutamate receptor subtype 5 is neuroprotective V Bruno, I Ksiazek, G Battaglia, S Lukic, T Leonhardt, D Sauer, ... Neuropharmacology 39 (12), 2223-2230, 2000 | 154 | 2000 |