| Ceramide glycosylation potentiates cellular multidrug resistance YYU LIU, TIEYAN HAN, AE GIULIANO, MC CABOT The FASEB Journal 15 (3), 719-730, 2001 | 403 | 2001 |
| Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells YY Liu, TY Han, AE Giuliano, MC Cabot Journal of Biological Chemistry 274 (2), 1140-1146, 1999 | 345 | 1999 |
| Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs V Gouazé, YY Liu, CS Prickett, JY Yu, AE Giuliano, MC Cabot Cancer research 65 (9), 3861-3867, 2005 | 215 | 2005 |
| Taxol-induced ceramide generation and apoptosis in human breast cancer cells AG Charles, TY Han, YY Liu, N Hansen, AE Giuliano, MC Cabot Cancer chemotherapy and pharmacology 47, 444-450, 2001 | 201 | 2001 |
| Overexpression of glucosylceramide synthase and P-glycoprotein in cancer cells selected for resistance to natural product chemotherapy V Gouaze, JY Yu, RJ Bleicher, TY Han, YY Liu, H Wang, MM Gottesman, ... Molecular cancer therapeutics 3 (5), 633-640, 2004 | 197 | 2004 |
| Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and β-catenin signaling YY Liu, V Gupta, GA Patwardhan, K Bhinge, Y Zhao, J Bao, H Mehendale, ... Molecular cancer 9, 1-15, 2010 | 189 | 2010 |
| A role for ceramide in driving cancer cell resistance to doxorubicin YY Liu, JY Yu, D Yin, GA Patwardhan, V Gupta, Y Hirabayashi, ... The FASEB Journal 22 (7), 2541-2551, 2008 | 177 | 2008 |
| Ceramide glycosylation catalyzed by glucosylceramide synthase and cancer drug resistance YY Liu, RA Hill, YT Li Advances in cancer research 117, 59-89, 2013 | 166 | 2013 |
| Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance YY Liu, TY Han, AE Giuliano, N Hansen, MC Cabot Journal of Biological Chemistry 275 (10), 7138-7143, 2000 | 166 | 2000 |
| Role and therapeutic targeting of the PI3K/Akt/mTOR signaling pathway in skin cancer: a review of current status and future trends on natural and synthetic agents therapy JC Chamcheu, T Roy, MB Uddin, S Banang-Mbeumi, RCN Chamcheu, ... Cells 8 (8), 803, 2019 | 159 | 2019 |
| Olive phenolics as c-Met inhibitors:(-)-Oleocanthal attenuates cell proliferation, invasiveness, and tumor growth in breast cancer models MR Akl, NM Ayoub, MM Mohyeldin, BA Busnena, AI Foudah, YY Liu, ... PloS one 9 (5), e97622, 2014 | 134 | 2014 |
| Multidrug resistance modulators and doxorubicin synergize to elevate ceramide levels and elicit apoptosis in drug‐resistant cancer cells A Lucci, TY Han, YY Liu, AE Giuliano, MC Cabot Cancer: Interdisciplinary International Journal of the American Cancer …, 1999 | 133 | 1999 |
| Modification of ceramide metabolism increases cancer cell sensitivity to cytotoxics. A Lucci, TY Han, YY Liu, AE Giuliano, MC Cabot International journal of oncology 15 (3), 541-547, 1999 | 129 | 1999 |
| SDZ PSC 833, the cyclosporine A analogue and multidrug resistance modulator, activates ceramide synthesis and increases vinblastine sensitivity in drug-sensitive and drug … MC Cabot, AE Giuliano, TY Han, YY Liu Cancer research 59 (4), 880-885, 1999 | 120 | 1999 |
| N-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing H Wang, BJ Maurer, YY Liu, E Wang, JC Allegood, S Kelly, H Symolon, ... Molecular cancer therapeutics 7 (9), 2967-2976, 2008 | 119 | 2008 |
| Sphingolipids and expression regulation of genes in cancer GA Patwardhan, YY Liu Progress in lipid research 50 (1), 104-114, 2011 | 117 | 2011 |
| Oligonucleotides blocking glucosylceramide synthase expression selectively reverse drug resistance in cancer cells YY Liu, TY Han, JY Yu, A Bitterman, A Le, AE Giuliano, MC Cabot Journal of lipid research 45 (5), 933-940, 2004 | 106 | 2004 |
| Glycosylation of ceramide potentiates cellular resistance to tumor necrosis factor-α-induced apoptosis YY Liu, TY Han, AE Giuliano, S Ichikawa, Y Hirabayashi, MC Cabot Experimental cell research 252 (2), 464-470, 1999 | 102 | 1999 |
| Suppression of glucosylceramide synthase restores p53-dependent apoptosis in mutant p53 cancer cells YY Liu, GA Patwardhan, K Bhinge, V Gupta, X Gu, SM Jazwinski Cancer research 71 (6), 2276-2285, 2011 | 93 | 2011 |
| An N6-methyladenosine at the transited codon 273 of p53 pre-mRNA promotes the expression of R273H mutant protein and drug resistance of cancer cells MB Uddin, KR Roy, SB Hosain, SK Khiste, RA Hill, SD Jois, Y Zhao, ... Biochemical pharmacology 160, 134-145, 2019 | 82 | 2019 |
Vineet GuptaPostdoctoral FellowVerified email at mdanderson.org
