| 15-Deoxy-Δ12,14-prostaglandin J2 inhibits multiple steps in the NF-κB signaling pathway DS Straus, G Pascual, M Li, JS Welch, M Ricote, CH Hsiang, ... Proceedings of the National Academy of Sciences 97 (9), 4844-4849, 2000 | 1317 | 2000 |
| Regulation of protein kinases: controlling activity through activation segment conformation B Nolen, S Taylor, G Ghosh Molecular cell 15 (5), 661-675, 2004 | 1292 | 2004 |
| Crystal structure of p50/p65 heterodimer of transcription factor NF-κB bound to DNA FE Chen, DB Huang, YQ Chen, G Ghosh Nature 391 (6665), 410-413, 1998 | 900 | 1998 |
| Transcriptional regulation via the NF-κB signaling module A Hoffmann, G Natoli, G Ghosh Oncogene 25 (51), 6706-6716, 2006 | 887 | 2006 |
| The crystal structure of the IκBα/NF-κB complex reveals mechanisms of NF-κB inactivation T Huxford, DB Huang, S Malek, G Ghosh Cell 95 (6), 759-770, 1998 | 857 | 1998 |
| Structure of NF-κB p50 homodimer bound to a κB site G Ghosh, GV Duyne, S Ghosh, PB Sigler Nature 373 (6512), 303-310, 1995 | 838 | 1995 |
| A fourth IκB protein within the NF-κB signaling module S Basak, H Kim, JD Kearns, V Tergaonkar, E O'Dea, SL Werner, ... Cell 128 (2), 369-381, 2007 | 502 | 2007 |
| Regulation of DNA binding by Rel/NF-κB transcription factors: structural views FE Chen, G Ghosh Oncogene 18 (49), 6845-6852, 1999 | 470 | 1999 |
| Activation of IKKα target genes depends on recognition of specific κB binding sites by RelB: p52 dimers G Bonizzi, M Bebien, DC Otero, KE Johnson‐Vroom, Y Cao, D Vu, ... The EMBO journal 23 (21), 4202-4210, 2004 | 444 | 2004 |
| A novel DNA recognition mode by the NF-κB p65 homodimer YQ Chen, S Ghosh, G Ghosh Nature structural biology 5 (1), 67-73, 1998 | 320 | 1998 |
| IκBβ, but not IκBα, functions as a classical cytoplasmic inhibitor of NF-κB dimers by masking both NF-κB nuclear localization sequences in resting cells S Malek, Y Chen, T Huxford, G Ghosh Journal of Biological Chemistry 276 (48), 45225-45235, 2001 | 293* | 2001 |
| The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus. FXD Zhou Z, Qiu J, Liu W, Zhou Y, Plocinik RM, Li H, Hu Q, Ghosh G, Adams JA ... Molecular Cell 47 (3), 422-33, 2012 | 278 | 2012 |
| PRMT5 dimethylates R30 of the p65 subunit to activate NF-κB H Wei, B Wang, M Miyagi, Y She, B Gopalan, DB Huang, G Ghosh, ... Proceedings of the National Academy of Sciences 110 (33), 13516-13521, 2013 | 263 | 2013 |
| Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly S Cho, A Hoang, R Sinha, XY Zhong, XD Fu, AR Krainer, G Ghosh Proceedings of the National Academy of Sciences 108 (20), 8233-8238, 2011 | 260 | 2011 |
| NF‐κB regulation: lessons from structures G Ghosh, VYF Wang, DB Huang, A Fusco Immunological reviews 246 (1), 36-58, 2012 | 256 | 2012 |
| Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2 JCK Ngo, S Chakrabarti, JH Ding, A Velazquez-Dones, B Nolen, ... Molecular cell 20 (1), 77-89, 2005 | 254 | 2005 |
| Phosphorylation mechanism and structure of serine‐arginine protein kinases G Ghosh, JA Adams The FEBS journal 278 (4), 587-597, 2011 | 242 | 2011 |
| NF‐κB dictates the degradation pathway of IκBα E Mathes, EL O'dea, A Hoffmann, G Ghosh The EMBO journal 27 (9), 1357-1367, 2008 | 229 | 2008 |
| IκBα functions through direct contacts with the nuclear localization signals and the DNA binding sequences of NF-κB S Malek, T Huxford, G Ghosh Journal of Biological Chemistry 273 (39), 25427-25435, 1998 | 225 | 1998 |
| Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones XY Zhong, JH Ding, JA Adams, G Ghosh, XD Fu Genes & development 23 (4), 482-495, 2009 | 222 | 2009 |
Tom HuxfordProfessor of Chemistry & Biochemistry, San Diego State UniversityVerified email at sdsu.edu
