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Christian Wölk
Christian Wölk
Senior Scientist, Institute of Pharmacy, Leipzig University
Verified email at medizin.uni-leipzig.de
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Year
Enhanced efficacy and drug delivery with lipid coated mesoporous silica nanoparticles in cancer therapy
MU Amin, S Ali, MY Ali, I Tariq, U Nasrullah, SR Pinnapreddy, C Wölk, ...
European Journal of Pharmaceutics and Biopharmaceutics 165, 31-40, 2021
442021
General synthesis and physicochemical characterisation of a series of peptide‐mimic lysine‐based amino‐functionalised lipids
C Wölk, S Drescher, A Meister, A Blume, A Langner, B Dobner
Chemistry–A European Journal 19 (38), 12824-12838, 2013
302013
Wavelength dependent photo-cytotoxicity to ovarian carcinoma cells using temoporfin loaded tetraether liposomes as efficient drug delivery system
S Ali, MU Amin, MY Ali, I Tariq, SR Pinnapireddy, L Duse, N Goergen, ...
European Journal of Pharmaceutics and Biopharmaceutics 150, 50-65, 2020
292020
Structure–function relationships of new lipids designed for DNA transfection
M Dittrich, M Heinze, C Wölk, SS Funari, B Dobner, H Möhwald, ...
ChemPhysChem 12 (12), 2328-2337, 2011
282011
Ultrasound-Responsive Smart Drug Delivery System of Lipid Coated Mesoporous Silica Nanoparticles
MU Amin, S Ali, I Tariq, MY Ali, SR Pinnapreddy, E Preis, C Wölk, ...
Pharmaceutics 13 (9), 1396, 2021
242021
Contact-Triggered Lipofection from Multilayer Films Designed as Surfaces for in Situ Transfection Strategies in Tissue Engineering
C Husteden, F Doberenz, N Goergen, SR Pinnapireddy, C Janich, ...
ACS applied materials & interfaces 12 (8), 8963-8977, 2020
232020
Synthesis and DNA transfection properties of new head group modified malonic acid diamides
C Wölk, M Heinze, P Kreideweiß, M Dittrich, G Brezesinski, A Langner, ...
International journal of Pharmaceutics 409 (1-2), 46-56, 2011
222011
Malonic acid based cationic lipids–The way to highly efficient DNA-carriers
C Wölk, C Janich, U Bakowsky, A Langner, G Brezesinski
Advances in colloid and interface science 248, 20-34, 2017
202017
Structures of malonic acid diamide/phospholipid composites and their lipoplexes
C Janich, S Taßler, A Meister, G Hause, J Schäfer, U Bakowsky, ...
Soft matter 12 (27), 5854-5866, 2016
202016
Composites of malonic acid diamides and phospholipids–Structural parameters for optimal transfection efficiency in A549 cells
C Janich, C Wölk, S Taßler, S Drescher, A Meister, G Brezesinski, ...
European Journal of Lipid Science and Technology 116 (9), 1184-1194, 2014
202014
Magnetic resonance activatable thermosensitive liposomes for controlled doxorubicin delivery
M Alawak, G Mahmoud, AA Dayyih, L Duse, SR Pinnapireddy, ...
Materials Science and Engineering: C 115, 111116, 2020
192020
A combined FTIR and DSC study on the bilayer-stabilising effect of electrostatic interactions in ion paired lipids
M Schmid, C Wölk, J Giselbrecht, KLA Chan, RD Harvey
Colloids and surfaces b: biointerfaces 169, 298-304, 2018
192018
Interaction of DNA with Cationic Lipid Mixtures Investigation at Langmuir Lipid Monolayers
C Janich, A Hädicke, U Bakowsky, G Brezesinski, C Wölk
Langmuir 33 (39), 10172-10183, 2017
182017
Engineering of Stable Cross-Linked Multilayers Based on Thermo-Responsive PNIPAM-Grafted-Chitosan/Heparin to Tailor Their Physiochemical Properties and …
YT Lu, K Zeng, B Fuhrmann, C Woelk, K Zhang, T Groth
ACS Applied Materials & Interfaces 14 (26), 29550-29562, 2022
172022
Composites of malonic acid diamides and phospholipids—Impact of lipoplex stability on transfection efficiency
C Janich, C Wölk, F Erdmann, T Groth, G Brezesinski, B Dobner, ...
Journal of Controlled Release 220, 295-307, 2015
172015
Establishment of a Synthetic In Vitro Lung Surfactant Model for Particle Interaction Studies on a Langmuir Film Balance
JJ Schüer, A Arndt, C Wölk, SR Pinnapireddy, U Bakowsky
Langmuir 36 (17), 4808-4819, 2020
162020
Investigation of binary lipid mixtures of a three-chain cationic lipid with phospholipids suitable for gene delivery
C Wölk, C Janich, A Meister, S Drescher, A Langner, G Brezesinski, ...
Bioconjugate chemistry 26 (12), 2461-2473, 2015
162015
The directional observation of highly dynamic membrane tubule formation induced by engulfed liposomes
X Zhang, L Dai, A Wang, C Wölk, B Dobner, G Brezesinski, Y Tang, ...
Scientific reports 5 (1), 16559, 2015
162015
Lamellar versus Micellar Structures—Aggregation Behavior of a Three‐Chain Cationic Lipid Designed for Nonviral Polynucleotide Transfer
C Wölk, C Janich, D Pawlowska, S Drescher, A Meister, G Hause, ...
ChemPhysChem 16 (10), 2115-2126, 2015
152015
A focus on critical aspects of uptake and transport of milk-derived extracellular vesicles across the Caco-2 intestinal barrier model
J Roerig, L Schiller, H Kalwa, G Hause, C Vissiennon, MC Hacker, C Wölk, ...
European Journal of Pharmaceutics and Biopharmaceutics 166, 61-74, 2021
142021
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