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Nicholas Topley
Nicholas Topley
Cardiff University School of Medicine
Verified email at cf.ac.uk
Title
Cited by
Cited by
Year
Morphologic changes in the peritoneal membrane of patients with renal disease
JD Williams, KJ Craig, N Topley, C Von Ruhland, M Fallon, GR Newman, ...
Journal of the American Society of Nephrology 13 (2), 470-479, 2002
11682002
Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation
SM Hurst, TS Wilkinson, RM McLoughlin, S Jones, S Horiuchi, ...
Immunity 14 (6), 705-714, 2001
10442001
The soluble interleukin 6 receptor: mechanisms of production and implications in disease
SA Jones, S Horiuchi, N Topley, N YAMAMOTO, GM Fuller
The FASEB Journal 15 (1), 43-58, 2001
8782001
The Euro-Balance Trial: the effect of a new biocompatible peritoneal dialysis fluid (balance) on the peritoneal membrane
JD Williams, N Topley, KJ Craig, RK Mackenzie, M Pischetsrieder, C Lage, ...
Kidney international 66 (1), 408-418, 2004
4702004
Encapsulating peritoneal sclerosis: definition, etiology, diagnosis, and treatment
Y Kawaguchi, H Kawanishi, S Mujais, N Topley, DG Oreopoulos
Peritoneal Dialysis International 20 (4_suppl), 43-55, 2000
4622000
IL-6 regulates neutrophil trafficking during acute inflammation via STAT3
CA Fielding, RM McLoughlin, L McLeod, CS Colmont, M Najdovska, ...
The journal of immunology 181 (3), 2189-2195, 2008
4522008
IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation
RM McLoughlin, BJ Jenkins, D Grail, AS Williams, CA Fielding, CR Parker, ...
Proceedings of the National Academy of Sciences 102 (27), 9589-9594, 2005
4282005
Interleukin 1-α and tumor necrosis factor-α induce oxygen radical production in mesangial cells
HH Radeke, B Meier, N Topley, J Flöge, GG Habermehl, K Resch
Kidney international 37 (2), 767-775, 1990
4001990
Interleukin-6 signaling drives fibrosis in unresolved inflammation
CA Fielding, GW Jones, RM McLoughlin, L McLeod, VJ Hammond, ...
Immunity 40 (1), 40-50, 2014
3662014
Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-β signaling
BJ Jenkins, D Grail, T Nheu, M Najdovska, B Wang, P Waring, M Inglese, ...
Nature medicine 11 (8), 845-852, 2005
3532005
Interplay between IFN-γ and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation
RM McLoughlin, J Witowski, RL Robson, TS Wilkinson, SM Hurst, ...
The Journal of clinical investigation 112 (4), 598-607, 2003
3462003
Soluble IL-6 receptor governs IL-6 activity in experimental arthritis: blockade of arthritis severity by soluble glycoprotein 130
MA Nowell, PJ Richards, S Horiuchi, N Yamamoto, S Rose-John, ...
The Journal of Immunology 171 (6), 3202-3209, 2003
3392003
The pathophysiology of the peritoneal membrane
O Devuyst, PJ Margetts, N Topley
Journal of the American Society of Nephrology 21 (7), 1077-1085, 2010
3242010
Human peritoneal mesothelial cells synthesize interleukin-6: induction by IL-1β and TNFα
N Topley, A Jörres, W Luttmann, MM Petersen, MJ Lang, KH Thierauch, ...
Kidney international 43 (1), 226-233, 1993
2931993
Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis
MA Nowell, AS Williams, SA Carty, J Scheller, AJ Hayes, GW Jones, ...
The Journal of Immunology 182 (1), 613-622, 2009
2402009
Regulation of pre–B cell colony‐enhancing factor by STAT‐3–dependent interleukin‐6 trans‐signaling: Implications in the pathogenesis of rheumatoid arthritis
MA Nowell, PJ Richards, CA Fielding, S Ognjanovic, N Topley, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2006
2352006
Interleukin-6 regulation of transforming growth factor (TGF)-β receptor compartmentalization and turnover enhances TGF-β1 signaling
XL Zhang, N Topley, T Ito, A Phillips
Journal of Biological Chemistry 280 (13), 12239-12245, 2005
2342005
Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells
GW Jones, RM McLoughlin, VJ Hammond, CR Parker, JD Williams, ...
The journal of immunology 184 (4), 2130-2139, 2010
2302010
The effect of dialysate on peritoneal phagocyte oxidative metabolism
N Topley, HMM Alobaidi, M Davies, GA Coles, JD Williams, D Lloyd
Kidney international 34 (3), 404-411, 1988
2171988
TPA-induced differentiation and adhesion of U937 cells: changes in ultrastructure, cytoskeletal organization and expression of cell surface antigens.
R Hass, H Bartels, N Topley, M Hadam, L Köhler, M Goppelt-Strübe, ...
European journal of cell biology 48 (2), 282-293, 1989
2071989
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