Anumantha Kanthasamy
Anumantha Kanthasamy
Professor of Biomedical Sciences, Iowa State University
Verified email at
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice
R Gordon, EA Albornoz, DC Christie, MR Langley, V Kumar, S Mantovani, ...
Science translational medicine 10 (465), eaah4066, 2018
Gut microbiome in health and disease: Linking the microbiome–gut–brain axis and environmental factors in the pathogenesis of systemic and neurodegenerative diseases
S Ghaisas, J Maher, A Kanthasamy
Pharmacology & therapeutics 158, 52-62, 2016
Mechanism of intranasal drug delivery directly to the brain
TP Crowe, MHW Greenlee, AG Kanthasamy, WH Hsu
Life sciences 195, 44-52, 2018
Mitochondria-targeted antioxidants for treatment of Parkinson's disease: preclinical and clinical outcomes
H Jin, A Kanthasamy, A Ghosh, V Anantharam, B Kalyanaraman, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (8 …, 2014
Neurotoxicity of pesticides
JR Richardson, V Fitsanakis, RHS Westerink, AG Kanthasamy
Acta neuropathologica 138, 343-362, 2019
NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: implications for cell death
PG Gunasekar, AG Kanthasamy, JL Borowitz, GE Isom
Journal of neurochemistry 65 (5), 2016-2021, 1995
Caspase-3-dependent proteolytic cleavage of protein kinase Cδ is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl …
V Anantharam, M Kitazawa, J Wagner, S Kaul, AG Kanthasamy
Journal of neuroscience 22 (5), 1738-1751, 2002
Dieldrin-induced neurotoxicity: relevance to Parkinson's disease pathogenesis
AG Kanthasamy, M Kitazawa, A Kanthasamy, V Anantharam
Neurotoxicology 26 (4), 701-719, 2005
Environmental neurotoxic pesticide increases histone acetylation to promote apoptosis in dopaminergic neuronal cells: relevance to epigenetic mechanisms of neurodegeneration
C Song, A Kanthasamy, V Anantharam, F Sun, AG Kanthasamy
Molecular pharmacology 77 (4), 621-632, 2010
Dieldrin-induced oxidative stress and neurochemical changes contribute to apoptopic cell death in dopaminergic cells
M Kitazawa, V Anantharam, AG Kanthasamy
Free Radical Biology and Medicine 31 (11), 1473-1485, 2001
Caspase‐3 dependent proteolytic activation of protein kinase Cδ mediates and regulates 1‐methyl‐4‐phenylpyridinium (MPP+)‐induced apoptotic cell death in …
S Kaul, A Kanthasamy, M Kitazawa, V Anantharam, AG Kanthasamy
European Journal of Neuroscience 18 (6), 1387-1401, 2003
Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson’s disease
S Sarkar, E Malovic, DS Harishchandra, S Ghaisas, N Panicker, A Charli, ...
npj Parkinson's Disease 3 (1), 30, 2017
Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cδ in dopaminergic cells: relevance to oxidative stress and dopaminergic …
M Kitazawa, V Anantharam, AG Kanthasamy
Neuroscience 119 (4), 945-964, 2003
Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease model
A Ghosh, K Chandran, SV Kalivendi, J Joseph, WE Antholine, CJ Hillard, ...
Free Radical Biology and Medicine 49 (11), 1674-1684, 2010
Manganese-induced neurotoxicity: new insights into the triad of protein misfolding, mitochondrial impairment, and neuroinflammation
DS Harischandra, S Ghaisas, G Zenitsky, H Jin, A Kanthasamy, ...
Frontiers in neuroscience 13, 465315, 2019
Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia
N Panicker, S Sarkar, DS Harischandra, M Neal, TI Kam, H Jin, ...
Journal of Experimental Medicine 216 (6), 1411-1430, 2019
α-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity
H Jin, A Kanthasamy, A Ghosh, Y Yang, V Anantharam, AG Kanthasamy
Journal of Neuroscience 31 (6), 2035-2051, 2011
Protein kinase Cδ is a key downstream mediator of manganese-induced apoptosis in dopaminergic neuronal cells
C Latchoumycandane, V Anantharam, M Kitazawa, Y Yang, ...
Journal of Pharmacology and Experimental Therapeutics 313 (1), 46-55, 2005
Neuroprotective effect of protein kinase Cδ inhibitor rottlerin in cell culture and animal models of Parkinson's disease
D Zhang, V Anantharam, A Kanthasamy, AG Kanthasamy
Journal of pharmacology and experimental therapeutics 322 (3), 913-922, 2007
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