| One-carbon metabolism in health and disease GS Ducker, JD Rabinowitz Cell metabolism 25 (1), 27-42, 2017 | 1585 | 2017 |
| Reversal of cytosolic one-carbon flux compensates for loss of the mitochondrial folate pathway GS Ducker, L Chen, RJ Morscher, JM Ghergurovich, M Esposito, X Teng, ... Cell metabolism 23 (6), 1140-1153, 2016 | 402 | 2016 |
| Myc and mTOR converge on a common node in protein synthesis control that confers synthetic lethality in Myc-driven cancers M Pourdehnad, ML Truitt, IN Siddiqi, GS Ducker, KM Shokat, D Ruggero Proceedings of the National Academy of Sciences 110 (29), 11988-11993, 2013 | 263 | 2013 |
| Serine metabolism supports macrophage IL-1β production AE Rodriguez, GS Ducker, LK Billingham, CA Martinez, N Mainolfi, V Suri, ... Cell metabolism 29 (4), 1003-1011. e4, 2019 | 232 | 2019 |
| Mitochondrial translation requires folate-dependent tRNA methylation RJ Morscher, GS Ducker, SHJ Li, JA Mayer, Z Gitai, W Sperl, ... Nature 554 (7690), 128-132, 2018 | 231 | 2018 |
| Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma GS Ducker, JM Ghergurovich, N Mainolfi, V Suri, SK Jeong, ... Proceedings of the National Academy of Sciences 114 (43), 11404-11409, 2017 | 227 | 2017 |
| The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure AA Cluntun, R Badolia, S Lettlova, KM Parnell, TS Shankar, NA Diakos, ... Cell metabolism 33 (3), 629-648. e10, 2021 | 150 | 2021 |
| The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile BT Wang, GS Ducker, AJ Barczak, R Barbeau, DJ Erle, KM Shokat Proceedings of the National Academy of Sciences 108 (37), 15201-15206, 2011 | 144 | 2011 |
| Regulation of tumor initiation by the mitochondrial pyruvate carrier CL Bensard, DR Wisidagama, KA Olson, JA Berg, NM Krah, JC Schell, ... Cell metabolism 31 (2), 284-300. e7, 2020 | 125 | 2020 |
| Incomplete inhibition of phosphorylation of 4E-BP1 as a mechanism of primary resistance to ATP-competitive mTOR inhibitors GS Ducker, CE Atreya, JP Simko, YK Hom, MR Matli, CH Benes, B Hann, ... Oncogene 33 (12), 1590-1600, 2014 | 100 | 2014 |
| SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia JC García-Cañaveras, O Lancho, GS Ducker, JM Ghergurovich, X Xu, ... Leukemia 35 (2), 377-388, 2021 | 83 | 2021 |
| Metabolic profiling reveals a dependency of human metastatic breast cancer on mitochondrial serine and one-carbon unit metabolism AM Li, GS Ducker, Y Li, JA Seoane, Y Xiao, S Melemenidis, Y Zhou, L Liu, ... Molecular Cancer Research 18 (4), 599-611, 2022 | 70 | 2022 |
| FLT3 Mutations at Diagnosis and Relapse in Acute Myeloid Leukemia: Cytogenetic and Pathologic Correlations, Including Cuplike Blast Morphology SR McCormick, MJ McCormick, PS Grutkoski, GS Ducker, N Banerji, ... Archives of pathology & laboratory medicine 134 (8), 1143-1151, 2010 | 69 | 2010 |
| Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis V Panic, S Pearson, J Banks, TS Tippetts, JN Velasco-Silva, S Lee, ... Elife 9, e52558, 2020 | 48 | 2020 |
| Novel Pyrrolo[3,2-d]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy AS Dekhne, K Shah, GS Ducker, JM Katinas, J Wong-Roushar, ... Molecular cancer therapeutics 18 (10), 1787-1799, 2019 | 47 | 2019 |
| An LC-MS chemical derivatization method for the measurement of five different one-carbon states of cellular tetrahydrofolate L Chen, GS Ducker, W Lu, X Teng, JD Rabinowitz Analytical and bioanalytical chemistry 409, 5955-5964, 2017 | 45 | 2017 |
| A patient-derived xenograft model of pancreatic neuroendocrine tumors identifies sapanisertib as a possible new treatment for everolimus-resistant tumors CE Chamberlain, MS German, K Yang, J Wang, H VanBrocklin, M Regan, ... Molecular cancer therapeutics 17 (12), 2702-2709, 2018 | 37 | 2018 |
| Synthesis and evaluation of indazole based analog sensitive Akt inhibitors T Okuzumi, GS Ducker, C Zhang, B Aizenstein, R Hoffman, KM Shokat Molecular Biosystems 6 (8), 1389-1402, 2010 | 28 | 2010 |
| Generation of a patient-derived chordoma xenograft and characterization of the phosphoproteome in a recurrent chordoma JM Davies, AE Robinson, C Cowdrey, PV Mummaneni, GS Ducker, ... Journal of neurosurgery 120 (2), 331-336, 2014 | 27 | 2014 |
| 5, 10-methenyltetrahydrofolate synthetase deficiency causes a neurometabolic disorder associated with microcephaly, epilepsy, and cerebral hypomyelination LH Rodan, W Qi, GS Ducker, D Demirbas, R Laine, E Yang, MA Walker, ... Molecular genetics and metabolism 125 (1-2), 118-126, 2018 | 26 | 2018 |
robert s. warrenuniversity of california san franciscoBestätigte E-Mail-Adresse bei ucsfmedctr.org
