Fabrizio d'Adda di Fagagna
Fabrizio d'Adda di Fagagna
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Cellular senescence: when bad things happen to good cells
J Campisi, F d'Adda di Fagagna
Nature reviews Molecular cell biology 8 (9), 729-740, 2007
A DNA damage checkpoint response in telomere-initiated senescence
FA Fagagna, PM Reaper, L Clay-Farrace, H Fiegler, P Carr, ...
Nature 426 (6963), 194-198, 2003
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
R Di Micco, M Fumagalli, A Cicalese, S Piccinin, P Gasparini, C Luise, ...
Nature 444 (7119), 638-642, 2006
Chemokine signaling via the CXCR2 receptor reinforces senescence
JC Acosta, A O'Loghlen, A Banito, MV Guijarro, A Augert, S Raguz, ...
cell 133 (6), 1006-1018, 2008
Living on a break: cellular senescence as a DNA-damage response
F D'adda Di Fagagna
Nature Reviews Cancer 8 (7), 512-522, 2008
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
R Di Micco, V Krizhanovsky, D Baker, F d’Adda di Fagagna
Nature reviews Molecular cell biology 22 (2), 75-95, 2021
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation
M Fumagalli, F Rossiello, M Clerici, S Barozzi, D Cittaro, JM Kaplunov, ...
Nature cell biology 14 (4), 355-365, 2012
Site-specific DICER and DROSHA RNA products control the DNA-damage response
S Francia, F Michelini, A Saxena, D Tang, M De Hoon, V Anelli, M Mione, ...
Nature 488 (7410), 231-235, 2012
Human cell senescence as a DNA damage response
T Von Zglinicki, G Saretzki, J Ladhoff, FA di Fagagna, SP Jackson
Mechanisms of ageing and development 126 (1), 111-117, 2005
Identification of a DNA nonhomologous end-joining complex in bacteria
GR Weller, B Kysela, R Roy, LM Tonkin, E Scanlan, M Della, SK Devine, ...
Science 297 (5587), 1686-1689, 2002
Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer
R Di Micco, G Sulli, M Dobreva, M Liontos, OA Botrugno, G Gargiulo, ...
Nature cell biology 13 (3), 292-302, 2011
Functional links between telomeres and proteins of the DNA-damage response
FA di Fagagna, SH Teo, SP Jackson
Genes & development 18 (15), 1781-1799, 2004
Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells
FA di Fagagna, MP Hande, WM Tong, D Roth, PM Lansdorp, ZQ Wang, ...
Current Biology 11 (15), 1192-1196, 2001
Functions of poly (ADP-ribose) polymerase in controlling telomere length and chromosomal stability
FA Fagagna, MP Hande, WM Tong, PM Lansdorp, ZQ Wang, SP Jackson
Nature genetics 23 (1), 76-80, 1999
Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks
F Michelini, S Pitchiaya, V Vitelli, S Sharma, U Gioia, F Pessina, M Cabrini, ...
Nature cell biology 19 (12), 1400-1411, 2017
Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation
M Ogrunc, R Di Micco, M Liontos, L Bombardelli, M Mione, M Fumagalli, ...
Cell Death & Differentiation 21 (6), 998-1012, 2014
Telomere dysfunction in ageing and age-related diseases
F Rossiello, D Jurk, JF Passos, F d’Adda di Fagagna
Nature cell biology 24 (2), 135-147, 2022
Crosstalk between chromatin state and DNA damage response in cellular senescence and cancer
G Sulli, R Di Micco, FA di Fagagna
Nature Reviews Cancer 12 (10), 709-720, 2012
Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors
F Pessina, F Giavazzi, Y Yin, U Gioia, V Vitelli, A Galbiati, S Barozzi, ...
Nature cell biology 21 (10), 1286-1299, 2019
Oncogene‐induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions
A Suram, J Kaplunov, PL Patel, H Ruan, A Cerutti, V Boccardi, ...
The EMBO journal 31 (13), 2839-2851, 2012
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