| Tissue-specific targeting of retroviral vectors through ligand-receptor interactions N Kasahara, AM Dozy, YW Kan Science 266 (5189), 1373-1376, 1994 | 614 | 1994 |
| Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa M Chen, N Kasahara, DR Keene, L Chan, WK Hoeffler, D Finlay, ... Nature genetics 32 (4), 670-675, 2002 | 291 | 2002 |
| L1 retrotransposition in nondividing and primary human somatic cells S Kubo, MC Seleme, HS Soifer, JLG Perez, JV Moran, HH Kazazian Jr, ... Proceedings of the National Academy of Sciences 103 (21), 8036-8041, 2006 | 233 | 2006 |
| Phase 1 trial of vocimagene amiretrorepvec and 5-fluorocytosine for recurrent high-grade glioma TF Cloughesy, J Landolfi, DJ Hogan, S Bloomfield, B Carter, CC Chen, ... Science translational medicine 8 (341), 341ra75-341ra75, 2016 | 198 | 2016 |
| Ligand-directed retroviral targeting of human breast cancer cells. X Han, N Kasahara, YW Kan Proceedings of the National Academy of Sciences 92 (21), 9747-9751, 1995 | 194 | 1995 |
| Identification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly (ADP-ribose) polymerase-1 B Li, S Navarro, N Kasahara, L Comai Journal of Biological Chemistry 279 (14), 13659-13667, 2004 | 183 | 2004 |
| A high-titer lentiviral production system mediates efficient transduction of differentiated cells including beating cardiac myocytes T Sakoda, N Kasahara, Y Hamamori, L Kedes Journal of molecular and cellular cardiology 31 (11), 2037-2047, 1999 | 173 | 1999 |
| Durable complete responses in some recurrent high-grade glioma patients treated with Toca 511+ Toca FC TF Cloughesy, J Landolfi, MA Vogelbaum, D Ostertag, JB Elder, ... Neuro-oncology 20 (10), 1383-1392, 2018 | 167 | 2018 |
| High resolution in vivo bioluminescent imaging for the study of bacterial tumour targeting M Cronin, AR Akin, SA Collins, J Meganck, JB Kim, CK Baban, SA Joyce, ... PloS one 7 (1), e30940, 2012 | 149 | 2012 |
| Design and selection of Toca 511 for clinical use: modified retroviral replicating vector with improved stability and gene expression OD Perez, CR Logg, K Hiraoka, O Diago, R Burnett, A Inagaki, D Jolson, ... Molecular Therapy 20 (9), 1689-1698, 2012 | 147 | 2012 |
| Brain tumor eradication and prolonged survival from intratumoral conversion of 5-fluorocytosine to 5-fluorouracil using a nonlytic retroviral replicating vector D Ostertag, KK Amundson, F Lopez Espinoza, B Martin, T Buckley, ... Neuro-oncology 14 (2), 145-159, 2011 | 147 | 2011 |
| Single-shot, multicycle suicide gene therapy by replication-competent retrovirus vectors achieves long-term survival benefit in experimental glioma CK Tai, WJ Wang, TC Chen, N Kasahara Molecular Therapy 12 (5), 842-851, 2005 | 146 | 2005 |
| Glucocorticoids inhibit developmental stage-specific osteoblast cell cycle: dissociation of cyclin A-cyclin-dependent kinase 2 from E2F4-p130 complexes E Smith, RA Redman, CR Logg, GA Coetzee, N Kasahara, B Frenkel Journal of Biological Chemistry 275 (26), 19992-20001, 2000 | 134 | 2000 |
| Intradermal injection of lentiviral vectors corrects regenerated human dystrophic epidermolysis bullosa skin tissue in vivo DT Woodley, DR Keene, T Atha, Y Huang, R Ram, N Kasahara, M Chen Molecular therapy 10 (2), 318-326, 2004 | 132 | 2004 |
| Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo V Reebye, P Sætrom, PJ Mintz, KW Huang, P Swiderski, L Peng, C Liu, ... Hepatology 59 (1), 216-227, 2014 | 128 | 2014 |
| Methods and compositions for modification of the HPRT locus GJ Cost, MC Holmes, N Kasahara, J Laganiere, JC Miller, D Paschon, ... US Patent 8,895,264, 2014 | 126 | 2014 |
| Methods and compositions for modification of the HPRT locus GJ Cost, MC Holmes, N Kasahara, J Laganiere, JC Miller, D Paschon, ... US Patent 9,222,105, 2015 | 122 | 2015 |
| Highly efficient and tumor-restricted gene transfer to malignant gliomas by replication-competent retroviral vectors WJ Wang, CK Tai, N Kasahara, TC Chen Human gene therapy 14 (2), 117-127, 2003 | 117 | 2003 |
| CREB is a critical regulator of normal hematopoiesis and leukemogenesis JC Cheng, K Kinjo, DR Judelson, J Chang, WS Wu, I Schmid, DB Shankar, ... Blood, The Journal of the American Society of Hematology 111 (3), 1182-1192, 2008 | 115 | 2008 |
| A uniquely stable replication-competent retrovirus vector achieves efficient gene delivery in vitro and in solid tumors CR Logg, CK Tai, A Logg, WF Anderson, N Kasahara Human gene therapy 12 (8), 921-932, 2001 | 111 | 2001 |
Shuji KuboHyogo Medical UniversityVerified email at hyo-med.ac.jp
