Thymoquinone triggers anti-apoptotic signaling targeting death ligand and apoptotic regulators in a model of hepatic ischemia reperfusion injury RM Abd El-Ghany, NM Sharaf, LA Kassem, LG Mahran, OA Heikal Drug Discov Ther 3 (6), 296-306, 2009 | 83 | 2009 |
Synthesis and isomerization of thienotriazolopyrimidine and thienotetrazolopyrimidine derivatives with potential anti‐inflammatory activity AE Rashad, OA Heikal, AOH El‐Nezhawy, FME Abdel‐Megeid Heteroatom Chemistry: An International Journal of Main Group Elements 16 (3 …, 2005 | 69 | 2005 |
Pharmacokinetic study of paeonimetabolin I, a major metabolite of paeoniflorin from paeony roots OA Heikal, T Akao, S Takeda, M HATTORI Biological and Pharmaceutical Bulletin 20 (5), 517-521, 1997 | 55 | 1997 |
Minocycline attenuates Aβ oligomers-induced pro-inflammatory phenotype in primary microglia while enhancing Aβ fibrils phagocytosis IA El-Shimy, OA Heikal, N Hamdi Neuroscience letters 609, 36-41, 2015 | 49 | 2015 |
Evaluation of in vitro mutagenicity and genotoxicity of magnetite nanoparticles IO Gomaa, MHA Kader, TAS Eldin, OA Heikal Drug discoveries & therapeutics 7 (3), 116-123, 2013 | 37 | 2013 |
Formulation and evaluation of metoclopramide solid lipid nanoparticles for rectal suppository RA Mohamed, HA Abass, MA Attia, OA Heikal Journal of Pharmacy and Pharmacology 65 (11), 1607-1621, 2013 | 34 | 2013 |
Effect of capsaicin on bile secretion in the rat OME Abdel Salam, OA Heikal, SM El-Shenawy Pharmacology 73 (3), 121-128, 2005 | 28 | 2005 |
Promising therapy for Alzheimer's disease targeting angiotensinconverting enzyme and the cyclooxygense-2 isoform. NS El Sayed, LA Kassem, OA Heikal Drug discoveries & therapeutics 3 (6), 2009 | 26 | 2009 |
Antiapoptotic effect of DDB against hepatic ischemia-reperfusion injury AA El-Bahy, LA Kassem, OA Heikal, LG Mahran The Journal of Toxicological Sciences 36 (2), 145-154, 2011 | 24 | 2011 |
The effect of thymoquinone, α7 receptor agonist and α7 receptor allosteric modulator on the cerebral cortex in experimentally induced Alzheimer’s disease in relation to MSCs … LIAE Fattah, MB Zickri, LA Aal, O Heikal, E Osama International Journal of Stem Cells 9 (2), 230, 2016 | 16 | 2016 |
Enhancement of cognitive functions by rice bran extract in a neuroinflammatory mouse model via regulation of PPARγ AO Mostafa, RM Abdel-Kader, OA Heikal Journal of functional foods 48, 314-321, 2018 | 14 | 2018 |
Possible role of rice bran extract in microglial modulation through PPAR-gamma receptors in alzheimer’s disease mice model SS El-Din, S Abd Elwahab, L Rashed, S Fayez, BE Aboulhoda, OA Heikal, ... Metabolic Brain Disease 36 (7), 1903-1915, 2021 | 11 | 2021 |
Rice bran extract protected against LPS-induced neuroinflammation in mice through targeting PPAR-γ nuclear receptor MA Abd El Fattah, YA Abdelhamid, MF Elyamany, OA Badary, OA Heikal Molecular Neurobiology 58, 1504-1516, 2021 | 9 | 2021 |
Computer-Assisted HPLC method development for determination of tolmetin and possible kinetic modulators of its oxidative metabolism in vivo R Hanafi, H Spahn-Langguth, L Mahran, O Heikal, A Hanafy, H Rieger, ... Chromatographia 75, 469-477, 2012 | 9 | 2012 |
Enzyme immunoassay for paeonimetabolin I, a major metabolite of paeoniflorin by intestinal bacteria H MIYASHIRO, H KATO, M KANAOKA, T AKAO, K KABASIII, T NAMBA Journal of Traditional Medicines 80 (73), 13-73, 1996 | 9 | 1996 |
Stabilized rice bran extract: acute and 28-day repeated dose oral toxicity with in vitro mutagenicity and genotoxicity study OA Heikal, MB Zickri, AM Helal, H El Askary, BL Fiebich, IEO Gomaa African Journal of Pharmacy and Pharmacology 9 (44), 1037-1050, 2015 | 8 | 2015 |
Application of biodegradable nanoparticles in liver targeting of tacrolimus NN Affifi, OA Heikal, RS Hanafi, SN Tammam AIP conference proceedings 1326 (1), 120-127, 2011 | 8 | 2011 |
Disposition of Paeoniflorin and Paeonimetabolin 1 in Rats after Oral Administration of Toki-Shakuyaku-San (TS) and Shakuyaku-Kanzo-To (SK) MR Meselhy, OA Heikal, T Akao Natural medicines= 生薬学雑誌 52 (3), 265-268, 1998 | 4 | 1998 |
Quantitative determination of paeoniflorin and its major metabolites, paeonimetabolin I, in the rat plasma by enzyme immunoassay H OA J Trad Med. 14, 34-40, 1997 | 4 | 1997 |
Phenolic glycosides and bioactive Mangifera indica L. Kernel extract as neuroprotective agents against LPS-induced Alzheimer's disease in rats AY Ragheb, MA El-Ansari, OA Heikal, AF Galal, AAA Salama, ... South African Journal of Botany 157, 37-43, 2023 | 2 | 2023 |