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Abdelbasset A Farahat
Abdelbasset A Farahat
Associate Professor of Pharmaceutical and Medicinal chemistry , California Northstate University
Verified email at cnsu.edu
Title
Cited by
Cited by
Year
G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo
R Simone, R Balendra, TG Moens, E Preza, KM Wilson, A Heslegrave, ...
EMBO molecular medicine 10 (1), 22-31, 2018
2062018
Pharmacological inhibition of the transcription factor PU. 1 in leukemia
I Antony-Debré, A Paul, J Leite, K Mitchell, HM Kim, LA Carvajal, ...
The Journal of clinical investigation 127 (12), 4297-4313, 2017
1052017
Synthesis, molecular modeling and anticancer activity of new coumarin containing compounds
SA Morsy, AA Farahat, MNA Nasr, AS Tantawy
Saudi Pharmaceutical Journal 25 (6), 873-883, 2017
772017
Structure-dependent inhibition of the ETS-family transcription factor PU. 1 by novel heterocyclic diamidines
M Munde, S Wang, A Kumar, CE Stephens, AA Farahat, DW Boykin, ...
Nucleic acids research 42 (2), 1379-1390, 2014
752014
Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines
R Nhili, P Peixoto, S Depauw, S Flajollet, X Dezitter, MM Munde, ...
Nucleic acids research 41 (1), 125-138, 2013
742013
Water-mediated binding of agents that target the DNA minor groove
Y Liu, A Kumar, S Depauw, R Nhili, MH David-Cordonnier, MP Lee, ...
Journal of the American Chemical Society 133 (26), 10171-10183, 2011
682011
2-Chloroquinoline-3-carbaldehydes: synthesis, reactions and applications
BF Abdel-Wahab, RE Khidre, AA Farahat, AAS El-Ahl
Arkivoc 1, 211-276, 2012
662012
Indole and benzimidazole bichalcophenes: Synthesis, DNA binding and antiparasitic activity
AA Farahat, MA Ismail, A Kumar, T Wenzler, R Brun, A Paul, WD Wilson, ...
European journal of medicinal chemistry 143, 1590-1596, 2018
632018
In Vitro and In Vivo Investigation of the Efficacy of Arylimidamide DB1831 and Its Mesylated Salt Form - DB1965 - against Trypanosoma cruzi Infection
CF da Silva, DGJ Batista, GM Oliveira, EM de Souza, ER Hammer, ...
PLoS One 7 (1), e30356, 2012
572012
Pyrazole-3 (4)-carbaldehyde: synthesis, reactions and biological activity.
BF Abdel-Wahab, RE Khidre, AA Farahat
ARKIVOC: Online Journal of Organic Chemistry, 2011
572011
Exploration of larger central ring linkers in furamidine analogues: synthesis and evaluation of their DNA binding, antiparasitic and fluorescence properties
AA Farahat, E Paliakov, A Kumar, AEM Barghash, FE Goda, HM Eisa, ...
Bioorganic & medicinal chemistry 19 (7), 2156-2167, 2011
482011
Synthesis and antiprotozoal activity of 2, 5-bis [amidinoaryl] thiazoles
D Branowska, AA Farahat, A Kumar, T Wenzler, R Brun, Y Liu, WD Wilson, ...
Bioorganic & medicinal chemistry 18 (10), 3551-3558, 2010
452010
DNA minor groove induced dimerization of heterocyclic cations: compound structure, binding affinity, and specificity for a TTAA site
M Munde, A Kumar, R Nhili, S Depauw, MH David-Cordonnier, MA Ismail, ...
Journal of molecular biology 402 (5), 847-864, 2010
442010
2-Amino-4-thiazolidinones: synthesis and reactions
MA Metwally, AA Farahat, BF Abdel-Wahab
Journal of Sulfur Chemistry 31 (4), 315-349, 2010
442010
Ethyl coumarin-3-carboxylate: synthesis and chemical properties
BF Abdel-Wahab, HA Mohamed, AA Farahat.
Organic. Communications. 2014, 7, 1-27. 7, 1-27, 2014
422014
1H‐Benzimidazole‐2‐acetonitriles as synthon in fused benzimidazole synthesis
KM Dawood, NM Elwan, AA Farahat, BF Abdel‐Wahab
Journal of Heterocyclic Chemistry 47 (2), 243-267, 2010
392010
The Thiophene “Sigma‐Hole” as a Concept for Preorganized, Specific Recognition of G⋅ C Base Pairs in the DNA Minor Groove
P Guo, A Paul, A Kumar, AA Farahat, D Kumar, S Wang, DW Boykin, ...
Chemistry–A European Journal 22 (43), 15404-15412, 2016
372016
Synthesis, DNA binding, fluorescence measurements and antiparasitic activity of DAPI related diamidines
AA Farahat, A Kumar, M Say, AEDM Barghash, FE Goda, HM Eisa, ...
Bioorganic & medicinal chemistry 18 (2), 557-566, 2010
372010
Synthesis and antimicrobial activity of certain benzimidazole and fused benzimidazole derivatives
HM Eisa, AM Barghash, SM Badr, AA Farahat
NISCAIR-CSIR, India, 2010
362010
Pharmacologic efficacy of PU. 1 inhibition by heterocyclic dications: a mechanistic analysis
DC Stephens, HM Kim, A Kumar, AA Farahat, DW Boykin, GM Poon
Nucleic acids research 44 (9), 4005-4013, 2016
352016
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