Human gastric cancer modelling using organoids T Seidlitz, SR Merker, A Rothe, F Zakrzewski, C von Neubeck, ... Gut 68 (2), 207-217, 2019 | 262 | 2019 |
Environment‐induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children T Bauer, S Trump, N Ishaque, L Thürmann, L Gu, M Bauer, M Bieg, Z Gu, ... Molecular Systems Biology 12 (3), 861, 2016 | 119 | 2016 |
Fungal alternative splicing is associated with multicellular complexity and virulence: a genome-wide multi-species study K Grützmann, K Szafranski, M Pohl, K Voigt, A Petzold, S Schuster DNA research 21 (1), 27-39, 2014 | 115 | 2014 |
Maternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications S Jahreis, S Trump, M Bauer, T Bauer, L Thürmann, R Feltens, Q Wang, ... Journal of Allergy and Clinical Immunology 141 (2), 741-753, 2018 | 105 | 2018 |
MEST mediates the impact of prenatal bisphenol A exposure on long-term body weight development KM Junge, B Leppert, S Jahreis, DK Wissenbach, R Feltens, K Grützmann, ... Clinical epigenetics 10, 1-12, 2018 | 90 | 2018 |
Alternative splicing of mutually exclusive exons—A review M Pohl, RH Bortfeldt, K Grützmann, S Schuster Biosystems 114 (1), 31-38, 2013 | 89 | 2013 |
Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia SL Latham, N Ehmke, PYA Reinke, MH Taft, D Eicke, T Reindl, W Stenzel, ... Nature communications 9 (1), 4250, 2018 | 51 | 2018 |
Targeted capture-based NGS is superior to multiplex PCR-based NGS for hereditary BRCA1 and BRCA2 gene analysis in FFPE tumor samples F Zakrzewski, L Gieldon, A Rump, M Seifert, K Grützmann, A Krüger, ... BMC cancer 19, 1-15, 2019 | 36 | 2019 |
Patient-derived organoids of cholangiocarcinoma CF Maier, L Zhu, LK Nanduri, D Kühn, S Kochall, ML Thepkaysone, ... International journal of molecular sciences 22 (16), 8675, 2021 | 28 | 2021 |
Endogenous metabolites and inflammasome activity in early childhood and links to respiratory diseases G Herberth, K Offenberg, U Rolle-Kampczyk, M Bauer, W Otto, S Röder, ... Journal of Allergy and Clinical Immunology 136 (2), 495-497, 2015 | 25 | 2015 |
Early-onset childhood atopic dermatitis is related to NLRP2 repression L Thürmann, K Grützmann, M Klös, M Bieg, M Winter, T Polte, T Bauer, ... Journal of Allergy and Clinical Immunology 141 (4), 1482-1485. e16, 2018 | 22 | 2018 |
Lactate dehydrogenases promote glioblastoma growth and invasion via a metabolic symbiosis J Guyon, I Fernandez‐Moncada, CM Larrieu, CL Bouchez, ... EMBO molecular medicine 14 (12), e15343, 2022 | 19 | 2022 |
Diminished PLK2 induces cardiac fibrosis and promotes atrial fibrillation SR Künzel, M Hoffmann, S Weber, K Künzel, S Kämmerer, M Günscht, ... Circulation research 129 (8), 804-820, 2021 | 19 | 2021 |
Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification C Tretter, N de Andrade Krätzig, M Pecoraro, S Lange, P Seifert, ... Nature Communications 14 (1), 4632, 2023 | 9 | 2023 |
Controlling distinct signaling states in cultured cancer cells provides a new platform for drug discovery SW Poser, O Otto, C Arps‐Forker, Y Ge, M Herbig, C Andree, ... The FASEB Journal 33 (8), 9235-9249, 2019 | 8 | 2019 |
The conjugated antimetabolite 5-FdU-ECyd and its cellular and molecular effects on platinum-sensitive vs.-resistant ovarian cancer cells in vitro S Schott, P Wimberger, B Klink, K Gruetzmann, J Puppe, US Wauer, ... Oncotarget 8 (44), 76935, 2017 | 8 | 2017 |
Combinatorics of aliphatic amino acids K Grützmann, S Böcker, S Schuster Naturwissenschaften 98, 79-86, 2011 | 8 | 2011 |
Plasma extracellular vesicle messenger RNA profiling identifies prognostic EV signature for non-invasive risk stratification for survival prediction of patients with pancreatic … Y Han, P Drobisch, A Krüger, D William, K Grützmann, L Böthig, H Polster, ... Journal of Hematology & Oncology 16 (1), 7, 2023 | 7 | 2023 |
Different effects of RNAi-mediated downregulation or chemical inhibition of NAMPT in an isogenic IDH mutant and wild-type glioma cell model M Clausing, D William, M Preussler, J Biedermann, K Grützmann, ... International Journal of Molecular Sciences 23 (10), 5787, 2022 | 5 | 2022 |
The effect of the triazene compound CT913 on ovarian cancer cells in vitro and its synergistic interaction with the PARP-inhibitor olaparib C Wichmann, DM Klotz, HJ Zeiler, RA Hilger, K Grützmann, A Krüger, ... Gynecologic Oncology 159 (3), 850-859, 2020 | 5 | 2020 |