G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo R Simone, R Balendra, TG Moens, E Preza, KM Wilson, A Heslegrave, ... EMBO molecular medicine 10 (1), 22-31, 2018 | 208 | 2018 |
Targeting multiple effector pathways in pancreatic ductal adenocarcinoma with a G-quadruplex-binding small molecule C Marchetti, KG Zyner, SA Ohnmacht, M Robson, SM Haider, JP Morton, ... Journal of medicinal chemistry 61 (6), 2500-2517, 2018 | 126 | 2018 |
A three-step model for protein–gold nanoparticle adsorption A Wang, K Vangala, T Vo, D Zhang, NC Fitzkee The Journal of Physical Chemistry C 118 (15), 8134-8142, 2014 | 109 | 2014 |
Using hydrogen–deuterium exchange to monitor protein structure in the presence of gold nanoparticles A Wang, T Vo, V Le, NC Fitzkee The Journal of Physical Chemistry B 118 (49), 14148-14156, 2014 | 36 | 2014 |
Asymmetrically substituted quadruplex-binding naphthalene diimide showing potent activity in pancreatic cancer models AA Ahmed, R Angell, S Oxenford, J Worthington, N Williams, N Barton, ... ACS Medicinal Chemistry Letters 11 (8), 1634-1644, 2020 | 29 | 2020 |
Biosensor-surface plasmon resonance: A strategy to help establish a new generation RNA-specific small molecules T Vo, A Paul, A Kumar, DW Boykin, WD Wilson Methods 167, 15-27, 2019 | 22 | 2019 |
Substituted naphthalenediimide compounds bind selectively to two human quadruplex structures with parallel topology T Vo, S Oxenford, R Angell, C Marchetti, SA Ohnmacht, WD Wilson, ... ACS Medicinal Chemistry Letters 11 (5), 991-999, 2020 | 19 | 2020 |
HNRNPH1 destabilizes the G-quadruplex structures formed by G-rich RNA sequences that regulate the alternative splicing of an oncogenic fusion transcript T Vo, T Brownmiller, K Hall, TL Jones, S Choudhari, I Grammatikakis, ... Nucleic Acids Research 50 (11), 6474-6496, 2022 | 16 | 2022 |
Electrostatic control of DNA intersegmental translocation by the ETS transcription factor ETV6 T Vo, S Wang, GMK Poon, WD Wilson Journal of Biological Chemistry 292 (32), 13187-13196, 2017 | 7 | 2017 |
G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo. EMBO Mol Med. 2018; 10 (1): 22–31 R Simone, R Balendra, TG Moens, E Preza, KM Wilson, A Heslegrave, ... EXPERT REVIEW OF NEUROTHERAPEUTICS 897, 0 | 4 | |
Salt bridge dynamics in protein/DNA recognition: a comparative analysis of Elk1 and ETV6 TD Vo, AL Schneider, WD Wilson, GMK Poon Physical Chemistry Chemical Physics 23 (24), 13490-13502, 2021 | 3 | 2021 |
Quantifying length-dependent DNA end-binding by nucleoproteins T Vo, AV Albrecht, WD Wilson, GMK Poon Biophysical chemistry 251, 106177, 2019 | 2 | 2019 |
Monitoring Protein Structure on the Surface of Gold Nanoparticles using NMR Spectroscopy A Wang, K Woods, T Vo, A Coats, NC Fitzkee Biophysical Journal 108 (2), 375a-376a, 2015 | 1 | 2015 |
DNA-facilitated target search by nucleoproteins: Extension of a biosensor-surface plasmon resonance method TD Vo, AL Schneider, GMK Poon, WD Wilson Analytical biochemistry 629, 114298, 2021 | | 2021 |
Target-specific inhibition of transcription factors by designed, synthetic DNA ligands WD Wilson, A Paul, P Guo, T Vo, N Harika, A Kumar, A Farahat, B Liu, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
Electrostatic control of binding interactions between ETS transcription factors proteins and theirs cognate DNA T Vo, S Wang, G Poon, WD Wilson ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
Understanding electrostatic effects on binding kinetics and affinities of ETS transcription factor proteins and DNA interaction T Vo, S Wang, G Poon, WD Wilson ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
How does rev regulate retroviral integration in HIV T Vo, N Fitzkee ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013 | | 2013 |
Supporting Information A Three-Step Model for Protein-Gold Nanoparticle Adsorption A Wang, K Vangala, T Vo, D Zhang, NC Fitzkee | | |
APPENDIX B. THE SEARCH FOR SELECTIVITY OF RNA G-QUADRUPLEXES BY SYNTHETIC COMPOUNDS T Vo, S Laughlin-Toth, S Neidle, DW Boykin, WD Wilson To Affinity & Beyond: Exploring Sequence Selectivity of Small Molecules for …, 0 | | |