| Efficacy and biological correlates of response in a phase II study of venetoclax monotherapy in patients with acute myelogenous leukemia M Konopleva, DA Pollyea, J Potluri, B Chyla, L Hogdal, T Busman, ... Cancer discovery 6 (10), 1106-1117, 2016 | 1011 | 2016 |
| Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur, J Cortes, ... Cancer discovery 4 (3), 362-375, 2014 | 713 | 2014 |
| A novel MCL1 inhibitor combined with venetoclax rescues venetoclax-resistant acute myelogenous leukemia HE Ramsey, MA Fischer, T Lee, AE Gorska, MP Arrate, L Fuller, KL Boyd, ... Cancer discovery 8 (12), 1566-1581, 2018 | 296 | 2018 |
| Blastic plasmacytoid dendritic cell neoplasm is dependent on BCL2 and sensitive to venetoclax J Montero, J Stephansky, T Cai, GK Griffin, L Cabal-Hierro, K Togami, ... Cancer discovery 7 (2), 156-164, 2017 | 199 | 2017 |
| Early changes in natural killer cell function indicate virologic response to interferon therapy for hepatitis C G Ahlenstiel, B Edlich, LJ Hogdal, Y Rotman, M Noureddin, JJ Feld, ... Gastroenterology 141 (4), 1231-1239. e2, 2011 | 177 | 2011 |
| MLL-rearranged acute lymphoblastic leukemias activate BCL-2 through H3K79 methylation and are sensitive to the BCL-2-specific antagonist ABT-199 JM Benito, L Godfrey, K Kojima, L Hogdal, M Wunderlich, H Geng, I Marzo, ... Cell reports 13 (12), 2715-2727, 2015 | 143 | 2015 |
| Decreased mitochondrial priming determines chemoresistance of colon cancer stem cells S Colak, CD Zimberlin, E Fessler, L Hogdal, PR Prasetyanti, CM Grandela, ... Cell Death & Differentiation 21 (7), 1170-1177, 2014 | 131 | 2014 |
| Effect of ribavirin on viral kinetics and liver gene expression in chronic hepatitis C Y Rotman, M Noureddin, JJ Feld, J Guedj, M Witthaus, H Han, YJ Park, ... Gut 63 (1), 161-169, 2014 | 67 | 2014 |
| Discovery and biological characterization of potent myeloid cell leukemia‐1 inhibitors T Lee, Z Bian, B Zhao, LJ Hogdal, JL Sensintaffar, CM Goodwin, J Belmar, ... FEBS letters 591 (1), 240-251, 2017 | 63 | 2017 |
| Diminished apoptotic priming and ATM signalling confer a survival advantage onto aged haematopoietic stem cells in response to DNA damage P Gutierrez-Martinez, L Hogdal, M Nagai, M Kruta, R Singh, K Sarosiek, ... Nature Cell Biology 20 (4), 413-421, 2018 | 62 | 2018 |
| Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia. Cancer Discov. 2014; 4: 362–375. doi: 10.1158/2159-8290 R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur, J Cortes, ... CD-13-0609.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 62 | |
| Safety, efficacy, and patient-reported outcomes of venetoclax in combination with azacitidine for the treatment of patients with higher-risk myelodysplastic syndrome: a phase … JS Garcia, AH Wei, U Borate, CY Fong, MR Baer, F Nolte, JG Jurcic, ... Blood 136, 55-57, 2020 | 61 | 2020 |
| Functionally identifiable apoptosis-insensitive subpopulations determine chemoresistance in acute myeloid leukemia PD Bhola, BG Mar, RC Lindsley, JA Ryan, LJ Hogdal, TT Vo, ... The Journal of clinical investigation 126 (10), 3827-3836, 2016 | 44 | 2016 |
| Pevonedistat and azacitidine upregulate NOXA (PMAIP1) to increase sensitivity to venetoclax in preclinical models of acute myeloid leukemia D Cojocari, BN Smith, JJ Purkal, MP Arrate, JD Huska, Y Xiao, A Gorska, ... Haematologica 107 (4), 825, 2022 | 26 | 2022 |
| Molecular responses are observed across mutational spectrum in treatment-naïve higher-risk myelodysplastic syndrome patients treated with venetoclax plus azacitidine JS Garcia, AH Wei, MA Jacoby, CY Fong, U Borate, MR Baer, ... Blood 138, 241, 2021 | 25 | 2021 |
| Overcoming mutational complexity in acute myeloid leukemia by inhibition of critical pathways Y Saito, Y Mochizuki, I Ogahara, T Watanabe, L Hogdal, S Takagi, K Sato, ... Science translational medicine 9 (413), eaao1214, 2017 | 22 | 2017 |
| Venetoclax and azacitidine in the treatment of patients with relapsed/refractory myelodysplastic syndrome AM Zeidan, U Borate, DA Pollyea, AM Brunner, F Roncolato, JS Garcia, ... Blood 138, 537, 2021 | 17 | 2021 |
| Hold on: Females modulate sperm depletion from storage sites in the fly Drosophila melanogaster MCB Qazi, L Hogdal Journal of insect physiology 56 (9), 1332-1340, 2010 | 16 | 2010 |
| Selective BCL-2 inhibition by ABT-199 causes on-target cell. death in acute myeloid leukemia. Cancer Discov. 2014; 4 (3): 362-75. doi: 10.1158/2159-8290 R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur CD-13-0609, 0 | 13 | |
| Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia. Cancer Discov. 2014; 4 (3): 362–75 R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur | 11 | |
Anthony LetaiProfessor of Medicine, Dana-Farber Cancer InstituteVerified email at dfci.harvard.edu
