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Jun Chen
Jun Chen
Verified email at upmc.edu
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Year
Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia
X Hu, P Li, Y Guo, H Wang, RK Leak, S Chen, Y Gao, J Chen
Stroke 43 (11), 3063-3070, 2012
14622012
Microglial and macrophage polarization—new prospects for brain repair
X Hu, RK Leak, Y Shi, J Suenaga, Y Gao, P Zheng, J Chen
Nature Reviews Neurology 11 (1), 56-64, 2015
12702015
Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia
J Chen, T Nagayama, K Jin, RA Stetler, RL Zhu, SH Graham, RP Simon
Journal of Neuroscience 18 (13), 4914-4928, 1998
9561998
Blood-brain barrier dysfunction and recovery after ischemic stroke
X Jiang, AV Andjelkovic, L Zhu, T Yang, MVL Bennett, J Chen, RF Keep, ...
Progress in neurobiology 163, 144-171, 2018
6952018
Programmed cell death in cerebral ischemia
SH Graham, J Chen
Journal of Cerebral Blood Flow & Metabolism 21 (2), 99-109, 2001
6902001
Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia.
G Yang, PH Chan, J Chen, E Carlson, SF Chen, P Weinstein, CJ Epstein, ...
Stroke 25 (1), 165-170, 1994
6731994
Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection
M Zhang, C An, Y Gao, RK Leak, J Chen, F Zhang
Progress in neurobiology 100, 30-47, 2013
6472013
Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures
T Nagayama, AD Sinor, RP Simon, J Chen, SH Graham, K Jin, ...
Journal of Neuroscience 19 (8), 2987-2995, 1999
6131999
In vivo delivery of a Bcl-xL fusion protein containing the TAT protein transduction domain protects against ischemic brain injury and neuronal apoptosis
G Cao, W Pei, H Ge, Q Liang, Y Luo, FR Sharp, A Lu, R Ran, SH Graham, ...
Journal of Neuroscience 22 (13), 5423-5431, 2002
5882002
Microglia/macrophage polarization dynamics in white matter after traumatic brain injury
G Wang, J Zhang, X Hu, L Zhang, L Mao, X Jiang, AKF Liou, RK Leak, ...
Journal of Cerebral Blood Flow & Metabolism 33 (12), 1864-1874, 2013
4712013
Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration
PS Vosler, CS Brennan, J Chen
Molecular neurobiology 38 (1), 78-100, 2008
4532008
Stress proteins and tolerance to focal cerebral ischemia
J Chen, SH Graham, RL Zhu, RP Simon
Journal of Cerebral Blood Flow & Metabolism 16 (4), 566-577, 1996
4501996
Ischemic tolerance in the brain
J Chen, R Simon
Neurology 48 (2), 306-311, 1997
4131997
Cyclooxygenase-2 inhibition prevents delayed death of CA1 hippocampal neurons following global ischemia
M Nakayama, K Uchimura, RL Zhu, T Nagayama, ME Rose, RA Stetler, ...
Proceedings of the National Academy of Sciences 95 (18), 10954-10959, 1998
4101998
To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways
AKF Liou, RS Clark, DC Henshall, XM Yin, J Chen
Progress in neurobiology 69 (2), 103-142, 2003
4032003
Early detection of DNA strand breaks in the brain after transient focal ischemia: implications for the role of DNA damage in apoptosis and neuronal cell death
J Chen, K Jin, M Chen, W Pei, K Kawaguchi, DA Greenberg, RP Simon
Journal of neurochemistry 69 (1), 232-245, 1997
3961997
Cerebral vascular disease and neurovascular injury in ischemic stroke
X Hu, TM De Silva, J Chen, FM Faraci
Circulation research 120 (3), 449-471, 2017
3862017
Interleukin-4 is essential for microglia/macrophage M2 polarization and long-term recovery after cerebral ischemia
X Liu, J Liu, S Zhao, H Zhang, W Cai, M Cai, X Ji, RK Leak, Y Gao, J Chen, ...
Stroke 47 (2), 498-504, 2016
3732016
Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury
G Cao, J Xing, X Xiao, AKF Liou, Y Gao, XM Yin, RSB Clark, SH Graham, ...
Journal of Neuroscience 27 (35), 9278-9293, 2007
3712007
Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury
RSB CLARK, PM KOCHANEK, M CHEN, SC WATKINS, DW MARION, ...
The FASEB journal 13 (8), 813-821, 1999
3661999
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